Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 513.5 BDBM251697

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251697 (US10100018, Example 33 | US9464060, 33) Show SMILES COc1ccccc1Oc1ccc(cc1)C(=O)N(CCCc1cccc(F)c1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28FNO5/c1-37-28-9-2-3-10-29(28)38-27-17-15-24(16-18-27)30(34)33(19-5-7-22-6-4-8-26(32)20-22)21-23-11-13-25(14-12-23)31(35)36/h2-4,6,8-18,20H,5,7,19,21H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251697 (US10100018, Example 33 | US9464060, 33) Show SMILES COc1ccccc1Oc1ccc(cc1)C(=O)N(CCCc1cccc(F)c1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28FNO5/c1-37-28-9-2-3-10-29(28)38-27-17-15-24(16-18-27)30(34)33(19-5-7-22-6-4-8-26(32)20-22)21-23-11-13-25(14-12-23)31(35)36/h2-4,6,8-18,20H,5,7,19,21H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251697 (US10100018, Example 33 | US9464060, 33) Show SMILES COc1ccccc1Oc1ccc(cc1)C(=O)N(CCCc1cccc(F)c1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28FNO5/c1-37-28-9-2-3-10-29(28)38-27-17-15-24(16-18-27)30(34)33(19-5-7-22-6-4-8-26(32)20-22)21-23-11-13-25(14-12-23)31(35)36/h2-4,6,8-18,20H,5,7,19,21H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 5 (Homo sapiens (Human))	BDBM251697 (US10100018, Example 33 | US9464060, 33) Show SMILES COc1ccccc1Oc1ccc(cc1)C(=O)N(CCCc1cccc(F)c1)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H28FNO5/c1-37-28-9-2-3-10-29(28)38-27-17-15-24(16-18-27)30(34)33(19-5-7-22-6-4-8-26(32)20-22)21-23-11-13-25(14-12-23)31(35)36/h2-4,6,8-18,20H,5,7,19,21H2,1H3,(H,35,36)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair