Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251681
(US10100018, Example 17 | US9464060, 17)Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251681
(US10100018, Example 17 | US9464060, 17)Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251681
(US10100018, Example 17 | US9464060, 17)Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM251681
(US10100018, Example 17 | US9464060, 17)Show SMILES OC(=O)c1ccc(CN(CCCc2cccc(F)c2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 Show InChI InChI=1S/C30H25F2NO4/c31-25-7-3-5-21(19-25)6-4-18-33(20-22-10-12-24(13-11-22)30(35)36)29(34)23-14-16-26(17-15-23)37-28-9-2-1-8-27(28)32/h1-3,5,7-17,19H,4,6,18,20H2,(H,35,36) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |