Compile Data Set for Download or QSAR

Found 134 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193014 (CHEMBL3942643 | US11155556, No. 9) Show SMILES CCC(=O)N1CCN(CC1)S(=O)(=O)c1cccc(Nc2ncc3N(C)C(=O)c4cc(C)ccc4N(C)c3n2)c1 Show InChI InChI=1S/C27H31N7O4S/c1-5-24(35)33-11-13-34(14-12-33)39(37,38)20-8-6-7-19(16-20)29-27-28-17-23-25(30-27)31(3)22-10-9-18(2)15-21(22)26(36)32(23)4/h6-10,15-17H,5,11-14H2,1-4H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193031 (CHEMBL3959351 | US11155556, No. 12) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)N3CCC(O)CC3)nc12 Show InChI InChI=1S/C25H28N6O4S/c1-16-7-8-21-20(13-16)24(33)30(3)22-15-26-25(28-23(22)29(21)2)27-17-5-4-6-19(14-17)36(34,35)31-11-9-18(32)10-12-31/h4-8,13-15,18,32H,9-12H2,1-3H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193032 (CHEMBL3979343 | US11155556, No. 2) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)N3CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C27H29N7O4S/c1-5-24(35)33-11-13-34(14-12-33)39(37,38)20-8-6-7-19(16-20)29-27-28-17-23-25(30-27)31(3)22-10-9-18(2)15-21(22)26(36)32(23)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193017 (CHEMBL3904942 | US11155556, No. 17) Show SMILES CN1c2ccccc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(N)(=O)=O)nc12 Show InChI InChI=1S/C19H18N6O3S/c1-24-15-9-4-3-8-14(15)18(26)25(2)16-11-21-19(23-17(16)24)22-12-6-5-7-13(10-12)29(20,27)28/h3-11H,1-2H3,(H2,20,27,28)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193016 (CHEMBL3889977 | US11155556, No. 3) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)N3CCC(CC3)NC(=O)C=C)nc12 Show InChI InChI=1S/C28H31N7O4S/c1-5-25(36)30-19-11-13-35(14-12-19)40(38,39)21-8-6-7-20(16-21)31-28-29-17-24-26(32-28)33(3)23-10-9-18(2)15-22(23)27(37)34(24)4/h5-10,15-17,19H,1,11-14H2,2-4H3,(H,30,36)(H,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193023 (CHEMBL3898901 | US11155556, No. 5) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)Nc3ccc(NC(=O)C=C)cc3)nc12 Show InChI InChI=1S/C29H27N7O4S/c1-5-26(37)31-19-10-12-20(13-11-19)34-41(39,40)22-8-6-7-21(16-22)32-29-30-17-25-27(33-29)35(3)24-14-9-18(2)15-23(24)28(38)36(25)4/h5-17,34H,1H2,2-4H3,(H,31,37)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193030 (CHEMBL3950648 | US11155556, No. 14) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12 Show InChI InChI=1S/C20H20N6O3S/c1-12-4-9-16-15(10-12)19(27)26(3)17-11-22-20(24-18(17)25(16)2)23-13-5-7-14(8-6-13)30(21,28)29/h4-11H,1-3H3,(H2,21,28,29)(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193020 (CHEMBL3907932 | US11155556, No. 7) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)Nc3cccc(NC(=O)C=C)c3)nc12 Show InChI InChI=1S/C29H27N7O4S/c1-5-26(37)31-19-8-6-10-21(15-19)34-41(39,40)22-11-7-9-20(16-22)32-29-30-17-25-27(33-29)35(3)24-13-12-18(2)14-23(24)28(38)36(25)4/h5-17,34H,1H2,2-4H3,(H,31,37)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193021 (CHEMBL3922919 | US11155556, No. 13) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(=O)(=O)N3CCC(O)CC3)nc12 Show InChI InChI=1S/C25H28N6O4S/c1-16-4-9-21-20(14-16)24(33)30(3)22-15-26-25(28-23(22)29(21)2)27-17-5-7-19(8-6-17)36(34,35)31-12-10-18(32)11-13-31/h4-9,14-15,18,32H,10-13H2,1-3H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50337135 (4-((5,11-dimethyl-6-oxo-6,11-dihydro-5H-benzo[e]py...) Show SMILES CN1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12 Show InChI InChI=1S/C19H18N6O3S/c1-24-15-6-4-3-5-14(15)18(26)25(2)16-11-21-19(23-17(16)24)22-12-7-9-13(10-8-12)29(20,27)28/h3-11H,1-2H3,(H2,20,27,28)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193018 (CHEMBL3986648 | US11155556, No. 10) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cccc(Nc2ncc3N(C)C(=O)c4cc(C)ccc4N(C)c3n2)c1 Show InChI InChI=1S/C25H29N7O3S/c1-17-8-9-21-20(14-17)24(33)31(4)22-16-26-25(28-23(22)30(21)3)27-18-6-5-7-19(15-18)36(34,35)32-12-10-29(2)11-13-32/h5-9,14-16H,10-13H2,1-4H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50512861 (CHEMBL4558527) Show SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(Nc2cccc(n2)N2CCCC2=O)nc1C |r| Show InChI InChI=1S/C27H29N5O4S2/c1-15-25(37-27(28-15)30-21-6-4-7-22(29-21)31-11-5-8-23(31)33)18-12-19-14-32(16(2)17-9-10-17)26(34)24(19)20(13-18)38(3,35)36/h4,6-7,12-13,16-17H,5,8-11,14H2,1-3H3,(H,28,29,30)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PIK3C2G (unknown origin) assessed as reduction in substrate phosphorylation by FRET Adapta assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00434 BindingDB Entry DOI: 10.7270/Q24Q7ZVJ
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Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193029 (CHEMBL3913941 | US11155556, No. 15) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(N)(=O)=O)nc12 Show InChI InChI=1S/C20H20N6O3S/c1-12-7-8-16-15(9-12)19(27)26(3)17-11-22-20(24-18(17)25(16)2)23-13-5-4-6-14(10-13)30(21,28)29/h4-11H,1-3H3,(H2,21,28,29)(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	75.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193012 (CHEMBL3926951 | US11155556, No. 6) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(=O)(=O)Nc3ccc(NC(=O)C=C)cc3)nc12 Show InChI InChI=1S/C29H27N7O4S/c1-5-26(37)31-19-7-9-21(10-8-19)34-41(39,40)22-13-11-20(12-14-22)32-29-30-17-25-27(33-29)35(3)24-15-6-18(2)16-23(24)28(38)36(25)4/h5-17,34H,1H2,2-4H3,(H,31,37)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193015 (CHEMBL3918001 | US11155556, No. 4) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(=O)(=O)N3CCC(CC3)NC(=O)C=C)nc12 Show InChI InChI=1S/C28H31N7O4S/c1-5-25(36)30-20-12-14-35(15-13-20)40(38,39)21-9-7-19(8-10-21)31-28-29-17-24-26(32-28)33(3)23-11-6-18(2)16-22(23)27(37)34(24)4/h5-11,16-17,20H,1,12-15H2,2-4H3,(H,30,36)(H,29,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193032 (CHEMBL3979343 | US11155556, No. 2) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3cccc(c3)S(=O)(=O)N3CCN(CC3)C(=O)C=C)nc12 Show InChI InChI=1S/C27H29N7O4S/c1-5-24(35)33-11-13-34(14-12-33)39(37,38)20-8-6-7-19(16-20)29-27-28-17-23-25(30-27)31(3)22-10-9-18(2)15-21(22)26(36)32(23)4/h5-10,15-17H,1,11-14H2,2-4H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50048418 (CHEMBL3360227) Show SMILES COc1cc(Nc2nccnc2NS(=O)(=O)c2cccc(N)c2)cc(OC)c1 Show InChI InChI=1S/C18H19N5O4S/c1-26-14-9-13(10-15(11-14)27-2)22-17-18(21-7-6-20-17)23-28(24,25)16-5-3-4-12(19)8-16/h3-11H,19H2,1-2H3,(H,20,22)(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University Tuebingen Curated by ChEMBL					Assay Description Inhibition of human GDT-fused recombinant PI3K-C2gamma assessed as residual activity by nonradiometric ADP-Glo assay				J Med Chem 58: 212-21 (2015) Article DOI: 10.1021/jm5006034 BindingDB Entry DOI: 10.7270/Q2HM5B2D
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Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193027 (CHEMBL3935895 | US11155556, No. 8) Show SMILES CN1c2ccc(C)cc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(=O)(=O)Nc3cccc(NC(=O)C=C)c3)nc12 Show InChI InChI=1S/C29H27N7O4S/c1-5-26(37)31-20-7-6-8-21(16-20)34-41(39,40)22-12-10-19(11-13-22)32-29-30-17-25-27(33-29)35(3)24-14-9-18(2)15-23(24)28(38)36(25)4/h5-17,34H,1H2,2-4H3,(H,31,37)(H,30,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	438	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193025 (CHEMBL3932938 | US11155556, No. 18) Show SMILES CN1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3C)S(N)(=O)=O)nc12 Show InChI InChI=1S/C20H20N6O3S/c1-12-10-13(30(21,28)29)8-9-15(12)23-20-22-11-17-18(24-20)25(2)16-7-5-4-6-14(16)19(27)26(17)3/h4-11H,1-3H3,(H2,21,28,29)(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	822	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50160074 (CHEMBL3785311) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)C2CCCC2)nc1C Show InChI InChI=1S/C23H25N3O5S2/c1-14-21(32-23(24-14)25-22(28)15-5-3-4-6-15)16-7-12-19(31-2)20(13-16)33(29,30)26-17-8-10-18(27)11-9-17/h7-13,15,26-27H,3-6H2,1-2H3,(H,24,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged recombinant human full length PI3KC2gamma expressed in baculovirus infected Sf21 insect cells preincubated for 15...				J Med Chem 59: 1830-9 (2016) Article DOI: 10.1021/acs.jmedchem.5b01311 BindingDB Entry DOI: 10.7270/Q29888W5
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50160075 (CHEMBL3786230) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)C(C)(C)C)nc1C Show InChI InChI=1S/C22H25N3O5S2/c1-13-19(31-21(23-13)24-20(27)22(2,3)4)14-6-11-17(30-5)18(12-14)32(28,29)25-15-7-9-16(26)10-8-15/h6-12,25-26H,1-5H3,(H,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged recombinant human full length PI3KC2gamma expressed in baculovirus infected Sf21 insect cells preincubated for 15...				J Med Chem 59: 1830-9 (2016) Article DOI: 10.1021/acs.jmedchem.5b01311 BindingDB Entry DOI: 10.7270/Q29888W5
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513328 (US11091472, Compound S-1) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)CC2CCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50193026 (CHEMBL3948672 | US11155556, No. 11) Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(Nc2ncc3N(C)C(=O)c4cc(C)ccc4N(C)c3n2)cc1 Show InChI InChI=1S/C25H29N7O3S/c1-17-5-10-21-20(15-17)24(33)31(4)22-16-26-25(28-23(22)30(21)3)27-18-6-8-19(9-7-18)36(34,35)32-13-11-29(2)12-14-32/h5-10,15-16H,11-14H2,1-4H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzymatic activities against PI3K-α, PI3K-β, PI3K-γ and PI3K-δ were tested in ADAPTA assays. Activity against AURKB and AURKB...				Citation and Details BindingDB Entry DOI: 10.7270/Q20868G7
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50274638 (CHEMBL4126156 | US10858355, Example 4) Show SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(NC(C)=O)nc1C |r| Show InChI InChI=1S/C20H23N3O4S2/c1-10-18(28-20(21-10)22-12(3)24)14-7-15-9-23(11(2)13-5-6-13)19(25)17(15)16(8-14)29(4,26)27/h7-8,11,13H,5-6,9H2,1-4H3,(H,21,22,24)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3KC2gamma (unknown origin)				J Med Chem 61: 5435-5441 (2018) Article DOI: 10.1021/acs.jmedchem.8b00447 BindingDB Entry DOI: 10.7270/Q27M0BFZ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50048416 (CHEMBL3360219) Show SMILES COc1ccc(OC)c(Nc2nccnc2NS(=O)(=O)c2cccc(NC(C)=O)c2)c1 Show InChI InChI=1S/C20H21N5O5S/c1-13(26)23-14-5-4-6-16(11-14)31(27,28)25-20-19(21-9-10-22-20)24-17-12-15(29-2)7-8-18(17)30-3/h4-12H,1-3H3,(H,21,24)(H,22,25)(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University Tuebingen Curated by ChEMBL					Assay Description Inhibition of human GDT-fused recombinant PI3K-C2gamma assessed as residual activity by nonradiometric ADP-Glo assay				J Med Chem 58: 212-21 (2015) Article DOI: 10.1021/jm5006034 BindingDB Entry DOI: 10.7270/Q2HM5B2D
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50048417 (CHEMBL3360221) Show SMILES COc1ccc(OC)c(Nc2nccnc2NS(=O)(=O)c2cccc(c2)C(O)=O)c1 Show InChI InChI=1S/C19H18N4O6S/c1-28-13-6-7-16(29-2)15(11-13)22-17-18(21-9-8-20-17)23-30(26,27)14-5-3-4-12(10-14)19(24)25/h3-11H,1-2H3,(H,20,22)(H,21,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University Tuebingen Curated by ChEMBL					Assay Description Inhibition of human GDT-fused recombinant PI3K-C2gamma assessed as residual activity by nonradiometric ADP-Glo assay				J Med Chem 58: 212-21 (2015) Article DOI: 10.1021/jm5006034 BindingDB Entry DOI: 10.7270/Q2HM5B2D
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM60631 (BDBM50447096 | US9133168, 19b) Show SMILES C[C@H]1Cc2ccccc2N1C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Curated by ChEMBL					Assay Description Inhibition of PI3KC2gamma (unknown origin)				J Med Chem 57: 903-20 (2014) Article DOI: 10.1021/jm401642q BindingDB Entry DOI: 10.7270/Q2R212VJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513435 (US11091472, Compound S-231) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1C)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513389 (US11091472, Compound S-160) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CCNCC1)-c1sc(NC(=O)CCC2CCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513444 (US11091472, Compound S-263) Show SMILES COc1ncc(cc1S(=O)(=O)NC1CCCC(O)C1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513443 (US11091472, Compound S-262) Show SMILES COc1ncc(cc1S(=O)(=O)N[C@@H]1CC[C@H](O)CC1)-c1sc(NC(=O)CC2CCOCC2)nc1C |r,wU:12.12,15.16,(-8.95,-1.08,;-7.77,-2.07,;-6.44,-1.3,;-6.44,.24,;-5.11,1.01,;-3.77,.24,;-3.77,-1.3,;-5.11,-2.07,;-5.11,-3.61,;-6.65,-3.61,;-5.5,-5.1,;-3.77,-4.38,;-2.23,-4.38,;-1.46,-5.72,;.08,-5.72,;.85,-4.38,;2.39,-4.38,;.08,-3.05,;-1.46,-3.05,;-2.44,1.01,;-1.03,.38,;-0,1.52,;1.53,1.36,;2.62,2.45,;2.22,3.94,;4.11,2.05,;5.2,3.14,;6.68,2.74,;7.77,3.83,;7.37,5.32,;5.89,5.72,;4.8,4.63,;-.77,2.86,;-2.28,2.54,;-3.42,3.57,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513442 (US11091472, Compound S-261) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50121212 (CHEMBL3622372) Show SMILES C[C@@H]1COCCN1c1cc(=O)n2CC[C@H](N(Cc3cncc(Cl)c3)c2n1)C(F)(F)F |r| Show InChI InChI=1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curtin University Curated by ChEMBL					Assay Description Inhibition of PI3KC2gamma (unknown origin)				J Med Chem 60: 47-65 (2017) Article DOI: 10.1021/acs.jmedchem.6b00963 BindingDB Entry DOI: 10.7270/Q2PG1TPX
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50197067 (CHEMBL3913746) Show SMILES CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1 Show InChI InChI=1S/C21H24ClN7O/c1-21(2,30)12-26-19-25-11-15(17(29-19)9-13-3-4-13)16-6-8-24-20(28-16)27-14-5-7-23-18(22)10-14/h5-8,10-11,13,30H,3-4,9,12H2,1-2H3,(H,25,26,29)(H,23,24,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Curtin University Curated by ChEMBL					Assay Description Inhibition of PI3KC2gamma (unknown origin)				J Med Chem 60: 47-65 (2017) Article DOI: 10.1021/acs.jmedchem.6b00963 BindingDB Entry DOI: 10.7270/Q2PG1TPX
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM50048419 (CHEMBL3360231) Show SMILES Oc1ccc(Cl)c(Nc2nccnc2NS(=O)(=O)c2ccccc2)c1 Show InChI InChI=1S/C16H13ClN4O3S/c17-13-7-6-11(22)10-14(13)20-15-16(19-9-8-18-15)21-25(23,24)12-4-2-1-3-5-12/h1-10,22H,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University Tuebingen Curated by ChEMBL					Assay Description Inhibition of human GDT-fused recombinant PI3K-C2gamma assessed as residual activity by nonradiometric ADP-Glo assay				J Med Chem 58: 212-21 (2015) Article DOI: 10.1021/jm5006034 BindingDB Entry DOI: 10.7270/Q2HM5B2D
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513440 (US11091472, Compound S-259) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1cccc(O)c1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513353 (US11091472, Compound S-100) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(C)nc1)-c1sc(NC(=O)CC2CCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513422 (US11091472, Compound S-215) Show SMILES COc1ccc(cc1S(=O)(=O)N[C@H]1CC[C@H](O)CC1)-c1sc(NC(C)C)nc1C |r,wU:12.12,wD:15.16,(-7.12,-.2,;-5.94,-1.18,;-4.61,-.41,;-4.61,1.13,;-3.27,1.9,;-1.94,1.13,;-1.94,-.41,;-3.27,-1.18,;-3.27,-2.72,;-4.81,-2.72,;-3.67,-4.21,;-1.94,-3.49,;-.4,-3.49,;.37,-2.16,;1.91,-2.16,;2.68,-3.49,;4.22,-3.49,;1.91,-4.83,;.37,-4.83,;-.61,1.9,;.8,1.27,;1.83,2.41,;3.36,2.25,;4.45,3.34,;5.94,2.94,;4.05,4.83,;1.06,3.75,;-.44,3.43,;-1.59,4.46,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513445 (US11091472, Compound S-265) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1cccc(c1)C(O)=O)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513431 (US11091472, Compound S-227) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(O)cc1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513423 (US11091472, Compound S-216) Show SMILES COc1ccc(cc1S(=O)(=O)N[C@H]1CC[C@H](O)CC1)-c1sc(NC(C)(C)C)nc1C |r,wU:12.12,wD:15.16,(-7.12,-.2,;-5.94,-1.18,;-4.61,-.41,;-4.61,1.13,;-3.27,1.9,;-1.94,1.13,;-1.94,-.41,;-3.27,-1.18,;-3.27,-2.72,;-4.81,-2.72,;-3.67,-4.21,;-1.94,-3.49,;-.4,-3.49,;.37,-2.16,;1.91,-2.16,;2.68,-3.49,;4.22,-3.49,;1.91,-4.83,;.37,-4.83,;-.61,1.9,;.8,1.27,;1.83,2.41,;3.36,2.25,;4.45,3.34,;5.94,2.94,;4.05,4.83,;5.79,4.11,;1.06,3.75,;-.44,3.43,;-1.59,4.46,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513366 (US11091472, Compound S-127) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CC1)-c1sc(NCC2CCCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513367 (US11091472, Compound S-128) Show SMILES COc1ccc(cc1S(=O)(=O)NCC1CCCCC1)-c1sc(NCC2CCCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513368 (US11091472, Compound S-129) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CCCC1)-c1sc(NC2CCCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513369 (US11091472, Compound S-131) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CCCCCC1)-c1sc(NC2CCCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513395 (US11091472, Compound S-170) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1ccc(F)cc1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513403 (US11091472, Compound S-193) Show SMILES COc1ccc(cc1S(=O)(=O)N[C@H]1CC[C@H](O)CC1)-c1sc(N[C@H](C)C2CCCCC2)nc1C |r,wU:12.12,wD:15.16,23.25,(-8.61,-.2,;-7.43,-1.18,;-6.09,-.41,;-6.09,1.13,;-4.76,1.9,;-3.43,1.13,;-3.43,-.41,;-4.76,-1.18,;-4.76,-2.72,;-6.3,-2.72,;-5.16,-4.21,;-3.43,-3.49,;-1.89,-3.49,;-1.12,-2.16,;.42,-2.16,;1.19,-3.49,;2.73,-3.49,;.42,-4.83,;-1.12,-4.83,;-2.09,1.9,;-.69,1.27,;.34,2.41,;1.88,2.25,;2.97,3.34,;2.57,4.83,;4.45,2.94,;4.85,1.46,;6.34,1.06,;7.43,2.15,;7.03,3.63,;5.54,4.03,;-.43,3.75,;-1.93,3.43,;-3.08,4.46,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513421 (US11091472, Compound S-214) Show SMILES COc1ccc(cc1S(=O)(=O)NC1CCC(O)C1)-c1sc(NCCC2CCCCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513439 (US11091472, Compound S-258 | US11091472, Compound ...) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (Homo sapiens (Human))	BDBM513394 (US11091472, Compound S-169) Show SMILES COc1ccc(cc1S(=O)(=O)Nc1cc(C)cc(O)c1)-c1sc(NC(=O)CC2CCOCC2)nc1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In some embodiments, the subject compounds inhibit a P14-kinase, as determined by a kinase activity assay, e.g., by an assay that determines the leve...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RF5Z5N
					More data for this Ligand-Target Pair

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