Compile Data Set for Download or QSAR

Found 229 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1/2/4'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222640 (CHEMBL415543) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H32N2O2S/c1-31-26-21-24(14-15-25(26)30)13-8-19-29(20-17-23-11-6-3-7-12-23)27(32)28-18-16-22-9-4-2-5-10-22/h2-7,9-12,14-15,21,30H,8,13,16-20H2,1H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222640 (CHEMBL415543) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H32N2O2S/c1-31-26-21-24(14-15-25(26)30)13-8-19-29(20-17-23-11-6-3-7-12-23)27(32)28-18-16-22-9-4-2-5-10-22/h2-7,9-12,14-15,21,30H,8,13,16-20H2,1H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222695 (CHEMBL155433) Show SMILES COc1cc(CCCN(C(c2ccccc2)c2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C32H34N2O2S/c1-36-30-24-26(19-20-29(30)35)14-11-23-34(32(37)33-22-21-25-12-5-2-6-13-25)31(27-15-7-3-8-16-27)28-17-9-4-10-18-28/h2-10,12-13,15-20,24,31,35H,11,14,21-23H2,1H3,(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222637 (CHEMBL154743) Show SMILES COc1cc(CCCN(CCc2ccc(cc2)[N+]([O-])=O)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31N3O4S/c1-34-26-20-23(11-14-25(26)31)8-5-18-29(19-16-22-9-12-24(13-10-22)30(32)33)27(35)28-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,28,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222696 (CHEMBL156041) Show SMILES COc1cc(CCCN(CCc2ccc(Cl)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31ClN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-22-9-12-24(28)13-10-22)27(33)29-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222635 (CHEMBL267205) Show SMILES COc1ccc(CCN(CCCc2ccc(O)c(OC)c2)C(\S)=N\CCc2ccccc2)cc1 Show InChI InChI=1S/C28H34N2O3S/c1-32-25-13-10-23(11-14-25)17-20-30(28(34)29-18-16-22-7-4-3-5-8-22)19-6-9-24-12-15-26(31)27(21-24)33-2/h3-5,7-8,10-15,21,31H,6,9,16-20H2,1-2H3,(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222647 (CHEMBL154990) Show SMILES COc1cc(CCCN(CCc2ccc(C)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-22-10-12-24(13-11-22)17-20-30(28(33)29-18-16-23-7-4-3-5-8-23)19-6-9-25-14-15-26(31)27(21-25)32-2/h3-5,7-8,10-15,21,31H,6,9,16-20H2,1-2H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222649 (CHEMBL155730) Show SMILES COc1cc(CCCN(Cc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C26H30N2O2S/c1-30-25-19-22(14-15-24(25)29)13-8-18-28(20-23-11-6-3-7-12-23)26(31)27-17-16-21-9-4-2-5-10-21/h2-7,9-12,14-15,19,29H,8,13,16-18,20H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222641 (CHEMBL157962) Show SMILES COc1cc(CCCN(CCc2ccc(F)cc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C27H31FN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-22-9-12-24(28)13-10-22)27(33)29-17-15-21-6-3-2-4-7-21/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222638 (CHEMBL422702) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C27H31ClN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-21-6-3-2-4-7-21)27(33)29-17-15-22-9-12-24(28)13-10-22/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222644 (CHEMBL434295) Show SMILES COc1cc(CCCN(C(C)C)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C22H30N2O2S/c1-17(2)24(22(27)23-14-13-18-8-5-4-6-9-18)15-7-10-19-11-12-20(25)21(16-19)26-3/h4-6,8-9,11-12,16-17,25H,7,10,13-15H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222648 (CHEMBL156693) Show SMILES COc1cc(CCCN(C2CCCCC2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C25H34N2O2S/c1-29-24-19-21(14-15-23(24)28)11-8-18-27(22-12-6-3-7-13-22)25(30)26-17-16-20-9-4-2-5-10-20/h2,4-5,9-10,14-15,19,22,28H,3,6-8,11-13,16-18H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222639 (CHEMBL356682) Show SMILES COc1cc(CCCN(CCCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-32-27-22-25(16-17-26(27)31)15-9-21-30(20-8-14-23-10-4-2-5-11-23)28(33)29-19-18-24-12-6-3-7-13-24/h2-7,10-13,16-17,22,31H,8-9,14-15,18-21H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222646 (CHEMBL157917) Show SMILES COc1cc(CCCN(CCc2ccccc2)C(\S)=N\CCc2ccc(F)cc2)ccc1O Show InChI InChI=1S/C27H31FN2O2S/c1-32-26-20-23(11-14-25(26)31)8-5-18-30(19-16-21-6-3-2-4-7-21)27(33)29-17-15-22-9-12-24(28)13-10-22/h2-4,6-7,9-14,20,31H,5,8,15-19H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222694 (CHEMBL158189) Show SMILES COc1cc(CCCCN(CCc2ccccc2)C(\S)=N\CCc2ccccc2)ccc1O Show InChI InChI=1S/C28H34N2O2S/c1-32-27-22-25(15-16-26(27)31)14-8-9-20-30(21-18-24-12-6-3-7-13-24)28(33)29-19-17-23-10-4-2-5-11-23/h2-7,10-13,15-16,22,31H,8-9,14,17-21H2,1H3,(H,29,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222691 (CHEMBL156927) Show SMILES CC(C)N(CCCc1ccc(O)c(O)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2O2S/c1-16(2)23(14-6-9-18-10-11-19(24)20(25)15-18)21(26)22-13-12-17-7-4-3-5-8-17/h3-5,7-8,10-11,15-16,24-25H,6,9,12-14H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222690 (CHEMBL345157) Show SMILES CCCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C23H32N2O2S/c1-3-4-16-25(23(28)24-15-14-19-9-6-5-7-10-19)17-8-11-20-12-13-21(26)22(18-20)27-2/h5-7,9-10,12-13,18,26H,3-4,8,11,14-17H2,1-2H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222645 (CHEMBL157918) Show SMILES COc1ccc(CCCN(C(C)C)C(\S)=N\CCc2ccccc2)cc1OC Show InChI InChI=1S/C23H32N2O2S/c1-18(2)25(23(28)24-15-14-19-9-6-5-7-10-19)16-8-11-20-12-13-21(26-3)22(17-20)27-4/h5-7,9-10,12-13,17-18H,8,11,14-16H2,1-4H3,(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222693 (CHEMBL157579) Show SMILES CCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C22H30N2O2S/c1-3-15-24(22(27)23-14-13-18-8-5-4-6-9-18)16-7-10-19-11-12-20(25)21(17-19)26-2/h4-6,8-9,11-12,17,25H,3,7,10,13-16H2,1-2H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224228 (CHEMBL46233) Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C26H36FN3O4S2/c1-25(2,3)20-10-9-18(19(13-20)16-34-23(31)26(4,5)6)15-29-24(35)28-14-17-8-11-22(21(27)12-17)30-36(7,32)33/h8-13,30H,14-16H2,1-7H3,(H2,28,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224175 (CHEMBL48061) Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C24H34FN3O3S2/c1-6-7-12-31-22-14-19(24(2,3)4)10-9-18(22)16-27-23(32)26-15-17-8-11-21(20(25)13-17)28-33(5,29)30/h8-11,13-14,28H,6-7,12,15-16H2,1-5H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222634 (CHEMBL157473) Show SMILES CCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2O2S/c1-3-23(21(26)22-14-13-17-8-5-4-6-9-17)15-7-10-18-11-12-19(24)20(16-18)25-2/h4-6,8-9,11-12,16,24H,3,7,10,13-15H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224176 (CHEMBL296963) Show SMILES NC(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C10H14N4O/c11-10(15)14-7-5-13(6-8-14)9-3-1-2-4-12-9/h1-4H,5-8H2,(H2,11,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222692 (CHEMBL348634) Show SMILES CCCCCCCCN(CCCc1ccc(O)c(OC)c1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C27H40N2O2S/c1-3-4-5-6-7-11-20-29(27(32)28-19-18-23-13-9-8-10-14-23)21-12-15-24-16-17-25(30)26(22-24)31-2/h8-10,13-14,16-17,22,30H,3-7,11-12,15,18-21H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50222643 (CHEMBL157688) Show SMILES CC(C)N(CCCc1ccc(O)cc1)C(\S)=N\CCc1ccccc1 Show InChI InChI=1S/C21H28N2OS/c1-17(2)23(16-6-9-19-10-12-20(24)13-11-19)21(25)22-15-14-18-7-4-3-5-8-18/h3-5,7-8,10-13,17,24H,6,9,14-16H2,1-2H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...				Bioorg Med Chem Lett 13: 601-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP7747
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley rat				Bioorg Med Chem Lett 13: 4389-93 (2003) BindingDB Entry DOI: 10.7270/Q2KH0QJX
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20321 (3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224229 (CHEMBL48998) Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H37N3O3S2/c1-24(2,3)17-31-22-14-20(25(4,5)6)11-10-19(22)16-27-23(32)26-15-18-8-12-21(13-9-18)28-33(7,29)30/h8-14,28H,15-17H2,1-7H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224232 (CHEMBL296729) Show SMILES COCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H33N3O4S2/c1-23(2,3)19-9-8-18(21(14-19)30-13-12-29-4)16-25-22(31)24-15-17-6-10-20(11-7-17)26-32(5,27)28/h6-11,14,26H,12-13,15-16H2,1-5H3,(H2,24,25,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224234 (CHEMBL45252) Show SMILES CCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C24H35N3O3S2/c1-6-7-14-30-22-15-20(24(2,3)4)11-10-19(22)17-26-23(31)25-16-18-8-12-21(13-9-18)27-32(5,28)29/h8-13,15,27H,6-7,14,16-17H2,1-5H3,(H2,25,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224196 (CHEMBL43723) Show SMILES CC(C)(C)COc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C25H36FN3O3S2/c1-24(2,3)16-32-22-13-19(25(4,5)6)10-9-18(22)15-28-23(33)27-14-17-8-11-21(20(26)12-17)29-34(7,30)31/h8-13,29H,14-16H2,1-7H3,(H2,27,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224230 (CHEMBL47282) Show SMILES CC(C)(C)C(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C26H37N3O4S2/c1-25(2,3)21-11-10-19(20(14-21)17-33-23(30)26(4,5)6)16-28-24(34)27-15-18-8-12-22(13-9-18)29-35(7,31)32/h8-14,29H,15-17H2,1-7H3,(H2,27,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224237 (CHEMBL431341) Show SMILES CCCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H37N3O3S2/c1-6-7-8-15-31-23-16-21(25(2,3)4)12-11-20(23)18-27-24(32)26-17-19-9-13-22(14-10-19)28-33(5,29)30/h9-14,16,28H,6-8,15,17-18H2,1-5H3,(H2,26,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.				Bioorg Med Chem Lett 14: 787-91 (2004) BindingDB Entry DOI: 10.7270/Q2R213KC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20315 (3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley rat				Bioorg Med Chem Lett 13: 4389-93 (2003) BindingDB Entry DOI: 10.7270/Q2KH0QJX
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224239 (CHEMBL295773) Show SMILES CCCCCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C26H39N3O3S2/c1-6-7-8-9-16-32-24-17-22(26(2,3)4)13-12-21(24)19-28-25(33)27-18-20-10-14-23(15-11-20)29-34(5,30)31/h10-15,17,29H,6-9,16,18-19H2,1-5H3,(H2,27,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224100 (CHEMBL44057) Show SMILES CC(C)(C)C(=O)Oc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C25H35N3O4S2/c1-24(2,3)19-11-10-18(21(14-19)32-22(29)25(4,5)6)16-27-23(33)26-15-17-8-12-20(13-9-17)28-34(7,30)31/h8-14,28H,15-16H2,1-7H3,(H2,26,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224235 (CHEMBL45417) Show SMILES CCCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H33N3O3S2/c1-6-13-29-21-14-19(23(2,3)4)10-9-18(21)16-25-22(30)24-15-17-7-11-20(12-8-17)26-31(5,27)28/h7-12,14,26H,6,13,15-16H2,1-5H3,(H2,24,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50223778 (CHEMBL164875) Show SMILES COc1cc(C\N=C(/S)NCc2ccc(cc2)C(C)(C)C)ccc1OS(C)(=O)=O Show InChI InChI=1S/C21H28N2O4S2/c1-21(2,3)17-9-6-15(7-10-17)13-22-20(28)23-14-16-8-11-18(19(12-16)26-4)27-29(5,24)25/h6-12H,13-14H2,1-5H3,(H2,22,23,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.				Bioorg Med Chem Lett 14: 787-91 (2004) BindingDB Entry DOI: 10.7270/Q2R213KC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224226 (CHEMBL45455) Show SMILES COc1cc(CC\N=C(/S)NCCc2ccccc2)ccc1O Show InChI InChI=1S/C18H22N2O2S/c1-22-17-13-15(7-8-16(17)21)10-12-20-18(23)19-11-9-14-5-3-2-4-6-14/h2-8,13,21H,9-12H2,1H3,(H2,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224238 (CHEMBL47602) Show SMILES CC(C)Oc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H33N3O3S2/c1-16(2)29-21-13-19(23(3,4)5)10-9-18(21)15-25-22(30)24-14-17-7-11-20(12-8-17)26-31(6,27)28/h7-13,16,26H,14-15H2,1-6H3,(H2,24,25,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224195 (CHEMBL48102) Show SMILES COCOc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C22H31N3O4S2/c1-22(2,3)18-9-8-17(20(12-18)29-15-28-4)14-24-21(30)23-13-16-6-10-19(11-7-16)25-31(5,26)27/h6-12,25H,13-15H2,1-5H3,(H2,23,24,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224194 (CHEMBL47473) Show SMILES CC(=O)OCc1cc(ccc1C\N=C(/S)NCc1ccc(NS(C)(=O)=O)cc1)C(C)(C)C Show InChI InChI=1S/C23H31N3O4S2/c1-16(27)30-15-19-12-20(23(2,3)4)9-8-18(19)14-25-22(31)24-13-17-6-10-21(11-7-17)26-32(5,28)29/h6-12,26H,13-15H2,1-5H3,(H2,24,25,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20284 (CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...) Show SMILES Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley rat				Bioorg Med Chem Lett 13: 4389-93 (2003) BindingDB Entry DOI: 10.7270/Q2KH0QJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20284 (CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...) Show SMILES Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Sookmyung Women's University Curated by ChEMBL					Assay Description Ability to inhibit [Ca2+] influx neonatal rat cultured spinal sensory neurons.				Bioorg Med Chem Lett 13: 1549-52 (2003) BindingDB Entry DOI: 10.7270/Q2571F5K
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20284 (CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...) Show SMILES Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM20284 (CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...) Show SMILES Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.				Bioorg Med Chem Lett 14: 787-91 (2004) BindingDB Entry DOI: 10.7270/Q2R213KC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50224193 (CHEMBL295302) Show SMILES CC(C)(C)c1ccc(C\N=C(/S)NCc2ccc(NS(C)(=O)=O)cc2)c(OCc2ccccc2)c1 Show InChI InChI=1S/C27H33N3O3S2/c1-27(2,3)23-13-12-22(25(16-23)33-19-21-8-6-5-7-9-21)18-29-26(34)28-17-20-10-14-24(15-11-20)30-35(4,31)32/h5-16,30H,17-19H2,1-4H3,(H2,28,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neurons				Bioorg Med Chem Lett 14: 1693-6 (2004) BindingDB Entry DOI: 10.7270/Q23B6294
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50139640 (CHEMBL165272 | N-4-Substituted-benzyl-N'-tert-buty...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(N)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)16-8-4-14(5-9-16)12-21-18(26)22-13-15-6-10-17(11-7-15)23-27(20,24)25/h4-11,23H,12-13H2,1-3H3,(H2,20,24,25)(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.				Bioorg Med Chem Lett 14: 787-91 (2004) BindingDB Entry DOI: 10.7270/Q2R213KC
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 229 total )  |  Next  |  Last  >>

Jump to: