Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with Target = 'Urea transporter 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575379 (CHEMBL4852814) Show SMILES CCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575376 (CHEMBL4854119) Show SMILES CCCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575413 (CHEMBL4877679) Show SMILES CCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3cc(F)c(F)cc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575384 (CHEMBL4866473) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3c(nnc23)C(C)C)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575409 (CHEMBL4863725) Show SMILES CCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3cc(C)c(C)cc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575378 (CHEMBL4849241) Show SMILES CCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575404 (CHEMBL4863558) Show SMILES CCCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575387 (CHEMBL4848036) Show SMILES CCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575377 (CHEMBL4874714) Show SMILES CCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4C)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575383 (CHEMBL4849781) Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3c(nnc23)C(C)C)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575382 (CHEMBL4864461) Show SMILES CC(C)c1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4C)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575386 (CHEMBL4852450) Show SMILES CCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575385 (CHEMBL4877290) Show SMILES CCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4C)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575403 (CHEMBL4877908) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575405 (CHEMBL4848692) Show SMILES CCCCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4C)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134204 (CHEMBL3740772) Show SMILES CC(=O)Nc1ccc2-c3ccc(NC(C)=O)cc3C(=O)c2c1 Show InChI InChI=1S/C17H14N2O3/c1-9(20)18-11-3-5-13-14-6-4-12(19-10(2)21)8-16(14)17(22)15(13)7-11/h3-8H,1-2H3,(H,18,20)(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575417 (CHEMBL4875031) Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1cccc(c1)N1CCCS1(=O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575399 (CHEMBL4849280) Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575411 (CHEMBL4861819) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(Oc2nc3cc(F)c(F)cc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575381 (CHEMBL4856839) Show SMILES CCOc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575408 (CHEMBL4859014) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(Oc2nc3cc(C)c(C)cc3n3c(nnc23)C(C)C)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575407 (CHEMBL4867965) Show SMILES CCc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3)nc3cc(C)c(C)cc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575380 (CHEMBL4852161) Show SMILES CCOc1nnc2c(Oc3ccc(NS(=O)(=O)c4cc(C)ccc4OC)cc3)nc3ccccc3n12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135099 (CHEMBL3739636) Show SMILES CS(=O)(=O)Nc1ccc2-c3ccc(NS(C)(=O)=O)cc3C(=O)c2c1 Show InChI InChI=1S/C15H14N2O5S2/c1-23(19,20)16-9-3-5-11-12-6-4-10(17-24(2,21)22)8-14(12)15(18)13(11)7-9/h3-8,16-17H,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575398 (CHEMBL4866155) Show SMILES Cc1ccc(C)c(c1)S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575412 (CHEMBL4866447) Show SMILES COc1ccc(C)cc1S(=O)(=O)Nc1ccc(Oc2nc3cc(F)c(F)cc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575415 (CHEMBL4864170) Show SMILES COc1ccc(nn1)-c1cccc(c1)-c1ccn(Cc2csc(C)n2)n1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135098 (CHEMBL3741585) Show SMILES NC(=O)Nc1ccc2-c3ccc(NC(N)=O)cc3C(=O)c2c1 Show InChI InChI=1S/C15H12N4O3/c16-14(21)18-7-1-3-9-10-4-2-8(19-15(17)22)6-12(10)13(20)11(9)5-7/h1-6H,(H3,16,18,21)(H3,17,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM41258 (MLS000065400 | N-(1,2-oxazol-3-yl)-2-phenyl-quinol...) Show SMILES O=C(Nc1ccon1)c1cc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C19H13N3O2/c23-19(21-18-10-11-24-22-18)15-12-17(13-6-2-1-3-7-13)20-16-9-5-4-8-14(15)16/h1-12H,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575406 (CHEMBL4866180) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(Oc2nc3cc(C)c(C)cc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575416 (CHEMBL4859518) Show SMILES COC(=O)c1sc2nc3CCN(Cc4ccccc4)Cc3cc2c1N Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575414 (CHEMBL4878494) Show SMILES CC(=O)Nc1ccc(cc1)-c1noc(n1)C1CCCN(C1)C(=O)c1ccccc1F Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115182 (N‐(4‐ethoxyphenyl)‐8‐metho...) Show SMILES CCOc1ccc(Nc2cc(nc3c(OC)cccc23)C(=O)N2CCCCC2)cc1 Show InChI InChI=1S/C24H27N3O3/c1-3-30-18-12-10-17(11-13-18)25-20-16-21(24(28)27-14-5-4-6-15-27)26-23-19(20)8-7-9-22(23)29-2/h7-13,16H,3-6,14-15H2,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115184 (8‐methoxy‐N‐(4‐methoxyphen...) Show SMILES COc1ccc(Nc2cc(nc3c(OC)cccc23)C(=O)N2CCSCC2)cc1 Show InChI InChI=1S/C22H23N3O3S/c1-27-16-8-6-15(7-9-16)23-18-14-19(22(26)25-10-12-29-13-11-25)24-21-17(18)4-3-5-20(21)28-2/h3-9,14H,10-13H2,1-2H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115190 (2‐(2‐{[(5E)‐2‐imino‐...) Show SMILES CC(=O)OCCOc1ccccc1\C=C1\SC(=N)NC1=O Show InChI InChI=1S/C14H14N2O4S/c1-9(17)19-6-7-20-11-5-3-2-4-10(11)8-12-13(18)16-14(15)21-12/h2-5,8H,6-7H2,1H3,(H2,15,16,18)/b12-8+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50322180 (3-(2,5-dimethylphenylsulfonyl)-N-isopropylthieno[2...) Show SMILES CC(C)Nc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1cc(C)ccc1C Show InChI InChI=1S/C18H19N5O2S2/c1-10(2)19-16-15-13(7-8-26-15)23-17(20-16)18(21-22-23)27(24,25)14-9-11(3)5-6-12(14)4/h5-10H,1-4H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115185 (8‐methoxy‐N‐[3‐(methylsulf...) Show SMILES COc1cccc2c(Nc3cccc(SC)c3)cc(nc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H25N3O2S/c1-28-21-11-7-10-18-19(24-16-8-6-9-17(14-16)29-2)15-20(25-22(18)21)23(27)26-12-4-3-5-13-26/h6-11,14-15H,3-5,12-13H2,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115194 (4‐(4,5‐dihydro‐1,3‐thiazol...) Show SMILES COc1ccc(Cc2nc(Nc3ccc(OC)c(OC)c3)nc(SC3=NCCS3)n2)cc1OC |t:25| Show InChI InChI=1S/C23H25N5O4S2/c1-29-16-7-5-14(11-18(16)31-3)12-20-26-21(28-22(27-20)34-23-24-9-10-33-23)25-15-6-8-17(30-2)19(13-15)32-4/h5-8,11,13H,9-10,12H2,1-4H3,(H,25,26,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115191 ((5E)‐5‐[(2‐hydroxy‐3‐...) Show SMILES COc1cccc(\C=C2\SC(=N)NC2=O)c1O Show InChI InChI=1S/C11H10N2O3S/c1-16-7-4-2-3-6(9(7)14)5-8-10(15)13-11(12)17-8/h2-5,14H,1H3,(H2,12,13,15)/b8-5+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575418 (CHEMBL4874369) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc2nc(SC)sc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575396 (CHEMBL4872678) Show SMILES Clc1ccccc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115183 (8‐hydroxy‐N‐[(3‐methoxyphe...) Show SMILES COc1cccc(CNC(=O)c2ccc3cccc(O)c3n2)c1 Show InChI InChI=1S/C18H16N2O3/c1-23-14-6-2-4-12(10-14)11-19-18(22)15-9-8-13-5-3-7-16(21)17(13)20-15/h2-10,21H,11H2,1H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575419 (CHEMBL4847861) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cccc(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115192 ((5E)‐5‐[(2,3‐dimethoxyphenyl)met...) Show SMILES COc1cccc(\C=C2\SC(=N)NC2=O)c1OC Show InChI InChI=1S/C12H12N2O3S/c1-16-8-5-3-4-7(10(8)17-2)6-9-11(15)14-12(13)18-9/h3-6H,1-2H3,(H2,13,14,15)/b9-6+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50575395 (CHEMBL4876728) Show SMILES Cc1ccccc1S(=O)(=O)Nc1ccc(Oc2nc3ccccc3n3cnnc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.8b00343 BindingDB Entry DOI: 10.7270/Q2QF8XPS
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134208 (CHEMBL3742039) Show SMILES FC(F)(F)C(=O)Nc1ccc2-c3ccc(NC(=O)C(F)(F)F)cc3C(=O)c2c1 Show InChI InChI=1S/C17H8F6N2O3/c18-16(19,20)14(27)24-7-1-3-9-10-4-2-8(25-15(28)17(21,22)23)6-12(10)13(26)11(9)5-7/h1-6H,(H,24,27)(H,25,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134205 (CHEMBL3741102) Show SMILES CCC(=O)Nc1ccc2-c3ccc(NC(=O)CC)cc3C(=O)c2c1 Show InChI InChI=1S/C19H18N2O3/c1-3-17(22)20-11-5-7-13-14-8-6-12(21-18(23)4-2)10-16(14)19(24)15(13)9-11/h5-10H,3-4H2,1-2H3,(H,20,22)(H,21,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50135104 (CHEMBL3741981) Show SMILES CC(=O)Nc1cccc(c1)C(=O)c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C17H16N2O3/c1-11(20)18-15-7-3-5-13(9-15)17(22)14-6-4-8-16(10-14)19-12(2)21/h3-10H,1-2H3,(H,18,20)(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM50134206 (CHEMBL3742032) Show SMILES CC(C)C(=O)Nc1ccc2-c3ccc(NC(=O)C(C)C)cc3C(=O)c2c1 Show InChI InChI=1S/C21H22N2O3/c1-11(2)20(25)22-13-5-7-15-16-8-6-14(23-21(26)12(3)4)10-18(16)19(24)17(15)9-13/h5-12H,1-4H3,(H,22,25)(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay				Medchemcomm 6: 1278-1284 (2015) BindingDB Entry DOI: 10.7270/Q2QR4ZZC
					More data for this Ligand-Target Pair
Urea transporter 2 (Rattus norvegicus (Rat))	BDBM115187 (N‐(3‐chloro‐4‐methoxypheny...) Show SMILES COc1ccc(Nc2cc(nc3c(OC)cccc23)C(=O)N2CCSCC2)cc1Cl Show InChI InChI=1S/C22H22ClN3O3S/c1-28-19-7-6-14(12-16(19)23)24-17-13-18(22(27)26-8-10-30-11-9-26)25-21-15(17)4-3-5-20(21)29-2/h3-7,12-13H,8-11H2,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California, San Francisco, San Francisco, CA 94143-0521, USA					Assay Description The urea concentration dependence of UT-A1 inhibition was studied from inhibitor concentration response data (0.3 - 60 µM) using different of ur...				Chem Biol 20: 1235-44 (2013) Article DOI: 10.1016/j.chembiol.2013.08.005 BindingDB Entry DOI: 10.7270/Q22F7M35
					More data for this Ligand-Target Pair

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