BindingDB PrimarySearch

Found 32 hits Enz. Inhib. hit(s) with Target = 'ATP-dependent Clp protease ATP-binding subunit ClpC1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	17.5	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540283 (CHEMBL4643756) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-493] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	19.2	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F2A] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F80A] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,E89A] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	127	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F2Y] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	780	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,F80Y] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	124	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145,E89Q] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	65	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540273 (CHEMBL4637575) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540274 (CHEMBL4641855) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540275 (CHEMBL4649631) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540276 (CHEMBL4643598) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540277 (CHEMBL4649342) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540278 (CHEMBL4647204) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540279 (CHEMBL4637113) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540280 (CHEMBL4648320) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540281 (CHEMBL4642233) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540282 (CHEMBL4638710) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540283 (CHEMBL4643756) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant Mycobacterium tuberculosis H37Rv N-terminal His6-tagged ClpC1 (1 to 145 residues) expressed in Escherichia coli BL21 ...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540273 (CHEMBL4637575) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540274 (CHEMBL4641855) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540275 (CHEMBL4649631) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540276 (CHEMBL4643598) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540277 (CHEMBL4649342) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540284 (CHEMBL4636448) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540278 (CHEMBL4647204) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540279 (CHEMBL4637113) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540280 (CHEMBL4648320) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540281 (CHEMBL4642233) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 (Mycobacterium tuberculosis)	BDBM50540282 (CHEMBL4638710) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Binding affinity to recombinant full length Mycobacterium tuberculosis H37Rv ClpC1 (1 to 842 residues) expressed in Escherichia coli BL21 cells by su...				J Nat Prod 83: 657-667 (2020) Article DOI: 10.1021/acs.jnatprod.9b01095 BindingDB Entry DOI: 10.7270/Q2959N3R
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent Clp protease ATP-binding subunit ClpC1 [1-145] (Mycobacterium tuberculosis)	BDBM213240 (Cyclomarin A1 (CymA1)) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	12	n/a	n/a	n/a	7.5	25
Novartis Institute for Tropical Diseases					Assay Description Isothermal titration calorimetry experiments were performed using an iTC200 (GEHealthcare) at 25 �C, with 15-20 μM ClpC1 (in 20 mM Tris-HCl, pH ...				J Biol Chem 288: 30883-91 (2013) Article DOI: 10.1074/jbc.M113.493767 BindingDB Entry DOI: 10.7270/Q2XW4HN6
Novartis Institute for Tropical Diseases					More data for this Ligand-Target Pair