Compile Data Set for Download or QSAR

Found 15 hits Enz. Inhib. hit(s) with Target = 'Endo-beta-N-acetylglucosaminidase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50304533 (2-((5R,6S,7R,8S)-8-acetamido-6,7-dihydroxy-5-methy...) Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)n2cc(CC(O)=O)nc12 |r| Show InChI InChI=1S/C12H17N3O6/c1-5(17)13-9-11(21)10(20)7(4-16)15-3-6(2-8(18)19)14-12(9)15/h3,7,9-11,16,20-21H,2,4H2,1H3,(H,13,17)(H,18,19)/t7-,9-,10+,11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.925	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Competitive inhibition of human placenta beta-N-acetylglucosaminidase by pNP-GlcNAc substrate hydrolysis assay				Bioorg Med Chem 17: 7248-53 (2009) Article DOI: 10.1016/j.bmc.2009.08.052 BindingDB Entry DOI: 10.7270/Q20865D3
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50304532 ((1R*, 3S*, 5S*, 6S*, 7R*, 7a S*)-5-acetamidomethyl...) Show SMILES CC(=O)NC[C@H]1[C@H](O)[C@H](O)[C@@H]2[C@H](O)C[C@@H](CO)N12 |r| Show InChI InChI=1S/C11H20N2O5/c1-5(15)12-3-7-10(17)11(18)9-8(16)2-6(4-14)13(7)9/h6-11,14,16-18H,2-4H2,1H3,(H,12,15)/t6-,7-,8+,9-,10-,11+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Mixed type inhibition of human placenta beta-N-acetylglucosaminidase by pNP-GlcNAc substrate hydrolysis assay				Bioorg Med Chem 17: 7248-53 (2009) Article DOI: 10.1016/j.bmc.2009.08.052 BindingDB Entry DOI: 10.7270/Q20865D3
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50304533 (2-((5R,6S,7R,8S)-8-acetamido-6,7-dihydroxy-5-methy...) Show SMILES CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)n2cc(CC(O)=O)nc12 |r| Show InChI InChI=1S/C12H17N3O6/c1-5(17)13-9-11(21)10(20)7(4-16)15-3-6(2-8(18)19)14-12(9)15/h3,7,9-11,16,20-21H,2,4H2,1H3,(H,13,17)(H,18,19)/t7-,9-,10+,11-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of human placenta beta-N-acetylglucosaminidase by pNP-GlcNAc substrate hydrolysis assay				Bioorg Med Chem 17: 7248-53 (2009) Article DOI: 10.1016/j.bmc.2009.08.052 BindingDB Entry DOI: 10.7270/Q20865D3
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50304532 ((1R*, 3S*, 5S*, 6S*, 7R*, 7a S*)-5-acetamidomethyl...) Show SMILES CC(=O)NC[C@H]1[C@H](O)[C@H](O)[C@@H]2[C@H](O)C[C@@H](CO)N12 |r| Show InChI InChI=1S/C11H20N2O5/c1-5(15)12-3-7-10(17)11(18)9-8(16)2-6(4-14)13(7)9/h6-11,14,16-18H,2-4H2,1H3,(H,12,15)/t6-,7-,8+,9-,10-,11+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.39	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of human placenta beta-N-acetylglucosaminidase by pNP-GlcNAc substrate hydrolysis assay				Bioorg Med Chem 17: 7248-53 (2009) Article DOI: 10.1016/j.bmc.2009.08.052 BindingDB Entry DOI: 10.7270/Q20865D3
					More data for this Ligand-Target Pair
Endo-beta-N-acetylglucosaminidase (Arthrobacter protophormiae)	BDBM50373151 (CHEMBL259756) Show SMILES CC1=N[C@H]2[C@@H](O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO[C@H]4O[C@H](CO[C@H]5O[C@H](CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H]5O)[C@@H]4O)[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C62H103NO49S/c1-12-63-23-33(80)47(19(8-70)106-62(23)113-12)107-59-46(93)50(110-60-52(39(86)28(75)16(5-67)101-60)112-61-51(38(85)27(74)17(6-68)102-61)111-57-43(90)36(83)26(73)15(4-66)99-57)32(79)22(105-59)11-96-55-44(91)49(109-58-45(92)48(30(77)18(7-69)100-58)108-56-42(89)35(82)25(72)14(3-65)98-56)31(78)21(104-55)10-95-54-41(88)37(84)29(76)20(103-54)9-94-53-40(87)34(81)24(71)13(2-64)97-53/h13-62,64-93H,2-11H2,1H3/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34+,35+,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase after 5 mins by HPAEC-PED method				Bioorg Med Chem 16: 4670-5 (2008) Article DOI: 10.1016/j.bmc.2008.02.032 BindingDB Entry DOI: 10.7270/Q2QJ7J55
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50373151 (CHEMBL259756) Show SMILES CC1=N[C@H]2[C@@H](O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO[C@H]4O[C@H](CO[C@H]5O[C@H](CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H]5O)[C@@H]4O)[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C62H103NO49S/c1-12-63-23-33(80)47(19(8-70)106-62(23)113-12)107-59-46(93)50(110-60-52(39(86)28(75)16(5-67)101-60)112-61-51(38(85)27(74)17(6-68)102-61)111-57-43(90)36(83)26(73)15(4-66)99-57)32(79)22(105-59)11-96-55-44(91)49(109-58-45(92)48(30(77)18(7-69)100-58)108-56-42(89)35(82)25(72)14(3-65)98-56)31(78)21(104-55)10-95-54-41(88)37(84)29(76)20(103-54)9-94-53-40(87)34(81)24(71)13(2-64)97-53/h13-62,64-93H,2-11H2,1H3/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34+,35+,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of human endo-beta-N-acetylglucosaminidase expressed in Hek293 cells after 3 mins				Bioorg Med Chem 16: 4670-5 (2008) Article DOI: 10.1016/j.bmc.2008.02.032 BindingDB Entry DOI: 10.7270/Q2QJ7J55
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50070209 (Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole) Show SMILES COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...				Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J
					More data for this Ligand-Target Pair
Endo-beta-N-acetylglucosaminidase (Arthrobacter protophormiae)	BDBM50373153 (CHEMBL261523) Show SMILES CC1=N[C@H]2[C@@H](O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C26H43NO19S/c1-6-27-11-15(34)21(9(4-30)44-26(11)47-6)45-25-20(39)22(46-24-19(38)17(36)13(32)8(3-29)42-24)14(33)10(43-25)5-40-23-18(37)16(35)12(31)7(2-28)41-23/h7-26,28-39H,2-5H2,1H3/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17+,18+,19+,20+,21-,22+,23+,24+,25+,26+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase after 5 mins by HPAEC-PED method				Bioorg Med Chem 16: 4670-5 (2008) Article DOI: 10.1016/j.bmc.2008.02.032 BindingDB Entry DOI: 10.7270/Q2QJ7J55
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50402289 (TENATOPRAZOLE) Show SMILES COc1ccc2[nH]c(nc2n1)S(=O)Cc1ncc(C)c(OC)c1C Show InChI InChI=1S/C16H18N4O3S/c1-9-7-17-12(10(2)14(9)23-4)8-24(21)16-18-11-5-6-13(22-3)19-15(11)20-16/h5-7H,8H2,1-4H3,(H,18,19,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...				Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50070208 (A-65006 | AG-1749 | CHEBI:6375 | Lansoprazole | Pr...) Show SMILES Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...				Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50247930 (Dexilant | Dexilant solutab | Dexlansoprazole | Ka...) Show SMILES Cc1c(OCC(F)(F)F)ccnc1C[S@@+]([O-])c1nc2ccccc2[nH]1 |r| Show InChI InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)/t25-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...				Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50103597 (Antra | CHEBI:77260 | H 168/68 | H-168/68 | Losec ...) Show SMILES COc1ccc2[nH]c(nc2c1)[S+]([O-])Cc1ncc(C)c(OC)c1C Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, United States. Curated by ChEMBL					Assay Description Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...				Bioorg Med Chem Lett 27: 2962-2966 (2017) Article DOI: 10.1016/j.bmcl.2017.05.010 BindingDB Entry DOI: 10.7270/Q2W66P5J
					More data for this Ligand-Target Pair
Endo-beta-N-acetylglucosaminidase (Arthrobacter protophormiae)	BDBM50373152 (CHEMBL260584) Show SMILES CC1=N[C@H]2[C@@H](O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H]2O)S1 |t:1| Show InChI InChI=1S/C14H23NO9S/c1-4-15-7-9(19)12(6(3-17)23-14(7)25-4)24-13-11(21)10(20)8(18)5(2-16)22-13/h5-14,16-21H,2-3H2,1H3/t5-,6-,7-,8-,9-,10+,11+,12-,13+,14+/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of Arthrobacter protophormiae endo-beta-N-acetylglucosaminidase after 5 mins by HPAEC-PED method				Bioorg Med Chem 16: 4670-5 (2008) Article DOI: 10.1016/j.bmc.2008.02.032 BindingDB Entry DOI: 10.7270/Q2QJ7J55
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50235890 ((2S,3S)-3-Hydroxybaikiain | (2S,3S)-3-hydroxy-1,2,...) Show SMILES O[C@H]1C=CCN[C@@H]1C(O)=O |r,c:2| Show InChI InChI=1S/C6H9NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-2,4-5,7-8H,3H2,(H,9,10)/t4-,5-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human placenta beta-N-acetylglucosaminidase				Bioorg Med Chem Lett 18: 1810-3 (2008) Article DOI: 10.1016/j.bmcl.2008.02.028 BindingDB Entry DOI: 10.7270/Q2MW2GWC
					More data for this Ligand-Target Pair
Cytosolic endo-beta-N-acetylglucosaminidase (Homo sapiens (Human))	BDBM50235890 ((2S,3S)-3-Hydroxybaikiain | (2S,3S)-3-hydroxy-1,2,...) Show SMILES O[C@H]1C=CCN[C@@H]1C(O)=O |r,c:2| Show InChI InChI=1S/C6H9NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-2,4-5,7-8H,3H2,(H,9,10)/t4-,5-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human Placental beta-N-acetylglucosaminidase				Bioorg Med Chem 16: 8273-86 (2008) Article DOI: 10.1016/j.bmc.2008.06.016 BindingDB Entry DOI: 10.7270/Q2F47P0Z
					More data for this Ligand-Target Pair