Found 5 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4-phosphate 5-kinase type-1 beta' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
(Homo sapiens) | BDBM50599594
(CHEMBL5171272)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557
BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
(Homo sapiens) | BDBM50599596
(CHEMBL5191668)Show SMILES CC(=O)Nc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557
BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
(Homo sapiens) | BDBM50599595
(CHEMBL5206569)Show SMILES CN(CC1OCCO1)C(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557
BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
(Homo sapiens) | BDBM50178832
(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)Show SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1 Show InChI InChI=1S/C21H20N4O2/c26-21(17-8-11-27-14-17)25-20-13-16(7-10-23-20)15-6-9-22-19(12-15)24-18-4-2-1-3-5-18/h1-7,9-10,12-13,17H,8,11,14H2,(H,22,24)(H,23,25,26) | MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557
BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
(Mus musculus (Mouse)) | BDBM217352
(GS-9820)Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1nc2ccc(F)cc2c(=O)n1-c1ccccc1 |r| | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Western University
| Assay Description
Biochemical in vitro lipid kinase assays were performed by the SelectScreenŽ biochemical kinase assay service (Invitrogen Ltd.). A stock solution of ... |
J Biol Chem 288: 35346-57 (2013)
Article DOI: 10.1074/jbc.M113.507525
BindingDB Entry DOI: 10.7270/Q28051F7 |
More data for this
Ligand-Target Pair | |
Search and Browse
