Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Protein Nef/Tyrosine-protein kinase HCK'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Nef/Tyrosine-protein kinase HCK (Homo sapiens (Human)-Human immunodeficiency virus ...)	BDBM36545 (DFP-4APF | diphenylfuropyrimidine-4-aminopropylfur...) Show SMILES C(CNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)Cc1ccco1 Show InChI InChI=1S/C25H21N3O2/c1-3-9-18(10-4-1)21-22-24(26-15-7-13-20-14-8-16-29-20)27-17-28-25(22)30-23(21)19-11-5-2-6-12-19/h1-6,8-12,14,16-17H,7,13,15H2,(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.				ACS Chem Biol 4: 939-47 (2009) Article DOI: 10.1021/cb900195c BindingDB Entry DOI: 10.7270/Q2PG1Q32
					More data for this Ligand-Target Pair
Protein Nef/Tyrosine-protein kinase HCK (Homo sapiens (Human)-Human immunodeficiency virus ...)	BDBM14807 (3-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-pr...) Show SMILES OCCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C21H19N3O2/c25-13-7-12-22-20-18-17(15-8-3-1-4-9-15)19(16-10-5-2-6-11-16)26-21(18)24-14-23-20/h1-6,8-11,14,25H,7,12-13H2,(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.				ACS Chem Biol 4: 939-47 (2009) Article DOI: 10.1021/cb900195c BindingDB Entry DOI: 10.7270/Q2PG1Q32
					More data for this Ligand-Target Pair
Protein Nef/Tyrosine-protein kinase HCK (Homo sapiens (Human)-Human immunodeficiency virus ...)	BDBM36544 (DFP-4AB | Diphenylfuropyrimidine-4-aminobutanol) Show SMILES OCCCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C22H21N3O2/c26-14-8-7-13-23-21-19-18(16-9-3-1-4-10-16)20(17-11-5-2-6-12-17)27-22(19)25-15-24-21/h1-6,9-12,15,26H,7-8,13-14H2,(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.				ACS Chem Biol 4: 939-47 (2009) Article DOI: 10.1021/cb900195c BindingDB Entry DOI: 10.7270/Q2PG1Q32
					More data for this Ligand-Target Pair
Protein Nef/Tyrosine-protein kinase HCK (Homo sapiens (Human)-Human immunodeficiency virus ...)	BDBM14806 (5,6-Diphenyl-furo[2,3-d]pyrimidin-4 -ylamine | 5,6...) Show SMILES Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C18H13N3O/c19-17-15-14(12-7-3-1-4-8-12)16(13-9-5-2-6-10-13)22-18(15)21-11-20-17/h1-11H,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	25
University of Pittsburgh School of Medicine					Assay Description In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.				ACS Chem Biol 4: 939-47 (2009) Article DOI: 10.1021/cb900195c BindingDB Entry DOI: 10.7270/Q2PG1Q32
					More data for this Ligand-Target Pair