Found 46 hits Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529621
(CHEMBL4563191)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H49NO4/c1-25(2)12-14-30(24(34)31-35)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(32)23(33)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,32-33,35H,9-17H2,1-7H3,(H,31,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529632
(CHEMBL4064111)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C30H46O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)17-25)16-20(31)23-27(5)10-9-22(32)26(3,4)21(27)8-11-29(23,28)7/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529624
(CHEMBL4473530)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C |r| Show InChI InChI=1S/C36H56O6/c1-21(2)22-12-17-36(30(40)41)19-18-34(8)23(28(22)36)10-11-25-33(7)15-14-26(42-27(37)20-31(3,4)29(38)39)32(5,6)24(33)13-16-35(25,34)9/h22-26,28H,1,10-20H2,2-9H3,(H,38,39)(H,40,41)/t22-,23?,24-,25+,26-,28-,33-,34+,35+,36-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529622
(CHEMBL4562991)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H47NO4/c1-25(2)12-14-30(24(34)31-35)15-13-28(6)18(19(30)17-25)16-20(32)23-27(5)10-9-22(33)26(3,4)21(27)8-11-29(23,28)7/h16,19,21-23,33,35H,8-15,17H2,1-7H3,(H,31,34)/t19-,21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529621
(CHEMBL4563191)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H49NO4/c1-25(2)12-14-30(24(34)31-35)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(32)23(33)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,32-33,35H,9-17H2,1-7H3,(H,31,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50329195
((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(=O)NO |r,t:19| Show InChI InChI=1S/C30H47NO4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)33)20(32)16-18-19-17-27(4,24(34)31-35)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,33,35H,8-15,17H2,1-7H3,(H,31,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529626
(CHEMBL4463388)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)Cc4cn[nH]c4C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C31H47N3O2/c1-18(2)20-10-13-31(26(35)34-36)15-14-29(6)21(24(20)31)8-9-23-28(5)16-19-17-32-33-25(19)27(3,4)22(28)11-12-30(23,29)7/h17,20-24,36H,1,8-16H2,2-7H3,(H,32,33)(H,34,35)/t20-,21?,22-,23+,24-,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529628
(CHEMBL4583726)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC\C(=N/O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C30H48N2O3/c1-18(2)19-10-15-30(25(33)32-35)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31-34)26(3,4)21(27)11-14-29(22,28)7/h19-22,24,34-35H,1,8-17H2,2-7H3,(H,32,33)/b31-23+/t19-,20?,21-,22+,24+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529629
(CHEMBL4472548)Show SMILES [H][C@]1(CC[C@]2(C)[C@]([H])(CC=C3[C@]4([H])CC(C)(C)CC[C@@]4(CC[C@@]23C)C(=O)OC)[C@@]1(C)CCC(=O)NO)C(C)=C |r,t:9| Show InChI InChI=1S/C31H49NO4/c1-20(2)21-11-14-30(7)24(28(21,5)13-12-25(33)32-35)10-9-22-23-19-27(3,4)15-17-31(23,26(34)36-8)18-16-29(22,30)6/h9,21,23-24,35H,1,10-19H2,2-8H3,(H,32,33)/t21-,23-,24+,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529631
(CHEMBL3754102)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H49NO3/c1-25(2)14-16-30(24(33)31-34)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(32)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,32,34H,9-18H2,1-7H3,(H,31,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529632
(CHEMBL4064111)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O |r,t:15| Show InChI InChI=1S/C30H46O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)17-25)16-20(31)23-27(5)10-9-22(32)26(3,4)21(27)8-11-29(23,28)7/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50148911
((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9| Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50329195
((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(=O)NO |r,t:19| Show InChI InChI=1S/C30H47NO4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)33)20(32)16-18-19-17-27(4,24(34)31-35)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,33,35H,8-15,17H2,1-7H3,(H,31,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529633
(CHEMBL3753400)Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)NO)[C@@]1(C)CC[C@H](O)C2(C)C |r,t:9| Show InChI InChI=1S/C30H49NO3/c1-18-10-15-30(25(33)31-34)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(32)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,32,34H,9-17H2,1-7H3,(H,31,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529627
(CHEMBL4464252)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)Cc4cnoc4C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C31H46N2O3/c1-18(2)20-10-13-31(26(34)33-35)15-14-29(6)21(24(20)31)8-9-23-28(5)16-19-17-32-36-25(19)27(3,4)22(28)11-12-30(23,29)7/h17,20-24,35H,1,8-16H2,2-7H3,(H,33,34)/t20-,21?,22-,23+,24-,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529634
(CHEMBL4459542)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC=CC(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r,c:20| Show InChI InChI=1S/C30H47NO2/c1-19(2)20-11-16-30(25(32)31-33)18-17-28(6)21(24(20)30)9-10-23-27(5)14-8-13-26(3,4)22(27)12-15-29(23,28)7/h8,13,20-24,33H,1,9-12,14-18H2,2-7H3,(H,31,32)/t20-,21?,22-,23+,24-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529630
(CHEMBL4589866)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC=CC(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,c:23,t:15| Show InChI InChI=1S/C30H47NO2/c1-25(2)15-17-30(24(32)31-33)18-16-28(6)20(21(30)19-25)9-10-23-27(5)13-8-12-26(3,4)22(27)11-14-29(23,28)7/h8-9,12,21-23,33H,10-11,13-19H2,1-7H3,(H,31,32)/t21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529635
(CHEMBL4519581)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC\C(=N/O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H48N2O3/c1-25(2)14-16-30(24(33)32-35)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31-34)26(3,4)21(27)10-13-29(22,28)7/h8,20-22,34-35H,9-18H2,1-7H3,(H,32,33)/b31-23+/t20-,21-,22+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529631
(CHEMBL3754102)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H49NO3/c1-25(2)14-16-30(24(33)31-34)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(32)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,32,34H,9-18H2,1-7H3,(H,31,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50233538
(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O |r,t:19| Show InChI InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM23208
((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C Show InChI InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
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Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529636
(CHEMBL4514184)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C30H49NO3/c1-18(2)19-10-15-30(25(33)31-34)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(32)26(3,4)21(27)11-14-29(22,28)7/h19-24,32,34H,1,8-17H2,2-7H3,(H,31,33)/t19-,20?,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529628
(CHEMBL4583726)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC\C(=N/O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C30H48N2O3/c1-18(2)19-10-15-30(25(33)32-35)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31-34)26(3,4)21(27)11-14-29(22,28)7/h19-22,24,34-35H,1,8-17H2,2-7H3,(H,32,33)/b31-23+/t19-,20?,21-,22+,24+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529625
(CHEMBL4436329)Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)NO)[C@@]1(C)CC\C(=N/O)C2(C)C |r,t:9| Show InChI InChI=1S/C30H48N2O3/c1-18-10-15-30(25(33)32-35)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31-34)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-22,24,34-35H,9-17H2,1-7H3,(H,32,33)/b31-23+/t18-,19+,21+,22-,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50175892
(2alpha,3beta-dihydroxy-12-oleanen-28-oic acid | 2a...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50346601
(NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529633
(CHEMBL3753400)Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)NO)[C@@]1(C)CC[C@H](O)C2(C)C |r,t:9| Show InChI InChI=1S/C30H49NO3/c1-18-10-15-30(25(33)31-34)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(32)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,32,34H,9-17H2,1-7H3,(H,31,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529636
(CHEMBL4514184)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C30H49NO3/c1-18(2)19-10-15-30(25(33)31-34)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(32)26(3,4)21(27)11-14-29(22,28)7/h19-24,32,34H,1,8-17H2,2-7H3,(H,31,33)/t19-,20?,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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| PC cid
PC sid
UniChem
| Article
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| n/a | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM23208
((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)Show SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C Show InChI InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1 | PDB
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| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529637
(CHEMBL4592450)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@]1([H])[C@]2(C)CCC(=O)OC1(C)C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H47NO4/c1-25(2)14-16-30(24(33)31-34)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(32)35-26(3,4)21(27)10-13-29(22,28)7/h8,20-22,34H,9-18H2,1-7H3,(H,31,33)/t20-,21-,22+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529626
(CHEMBL4463388)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)Cc4cn[nH]c4C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C31H47N3O2/c1-18(2)20-10-13-31(26(35)34-36)15-14-29(6)21(24(20)31)8-9-23-28(5)16-19-17-32-33-25(19)27(3,4)22(28)11-12-30(23,29)7/h17,20-24,36H,1,8-16H2,2-7H3,(H,32,33)(H,34,35)/t20-,21?,22-,23+,24-,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529629
(CHEMBL4472548)Show SMILES [H][C@]1(CC[C@]2(C)[C@]([H])(CC=C3[C@]4([H])CC(C)(C)CC[C@@]4(CC[C@@]23C)C(=O)OC)[C@@]1(C)CCC(=O)NO)C(C)=C |r,t:9| Show InChI InChI=1S/C31H49NO4/c1-20(2)21-11-14-30(7)24(28(21,5)13-12-25(33)32-35)10-9-22-23-19-27(3,4)15-17-31(23,26(34)36-8)18-16-29(22,30)6/h9,21,23-24,35H,1,10-19H2,2-8H3,(H,32,33)/t21-,23-,24+,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50148911
((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9| Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
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| Article
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| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529622
(CHEMBL4562991)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H47NO4/c1-25(2)12-14-30(24(34)31-35)15-13-28(6)18(19(30)17-25)16-20(32)23-27(5)10-9-22(33)26(3,4)21(27)8-11-29(23,28)7/h16,19,21-23,33,35H,8-15,17H2,1-7H3,(H,31,34)/t19-,21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529625
(CHEMBL4436329)Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@]5(CC[C@@]34C)C(=O)NO)[C@@]1(C)CC\C(=N/O)C2(C)C |r,t:9| Show InChI InChI=1S/C30H48N2O3/c1-18-10-15-30(25(33)32-35)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31-34)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-22,24,34-35H,9-17H2,1-7H3,(H,32,33)/b31-23+/t18-,19+,21+,22-,24+,27+,28-,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50233538
(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O |r,t:19| Show InChI InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1 | PDB
UniProtKB/SwissProt
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antibodypedia
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| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529627
(CHEMBL4464252)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)Cc4cnoc4C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r| Show InChI InChI=1S/C31H46N2O3/c1-18(2)20-10-13-31(26(34)33-35)15-14-29(6)21(24(20)31)8-9-23-28(5)16-19-17-32-36-25(19)27(3,4)22(28)11-12-30(23,29)7/h17,20-24,35H,1,8-16H2,2-7H3,(H,33,34)/t20-,21?,22-,23+,24-,28-,29+,30+,31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529630
(CHEMBL4589866)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC=CC(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,c:23,t:15| Show InChI InChI=1S/C30H47NO2/c1-25(2)15-17-30(24(32)31-33)18-16-28(6)20(21(30)19-25)9-10-23-27(5)13-8-12-26(3,4)22(27)11-14-29(23,28)7/h8-9,12,21-23,33H,10-11,13-19H2,1-7H3,(H,31,32)/t21-,22-,23+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50175892
(2alpha,3beta-dihydroxy-12-oleanen-28-oic acid | 2a...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| Show InChI InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
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UniChem
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Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529623
(CHEMBL4460360)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)OC |r,c:33,t:15| Show InChI InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-30(6)20(21(32)17-27)15-22(34)24-29(5)16-19(18-33)25(35)28(3,4)23(29)9-10-31(24,30)7/h15-16,21,23-24H,9-14,17H2,1-8H3/t21-,23-,24+,29-,30+,31+,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529634
(CHEMBL4459542)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC=CC(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO)C(C)=C |r,c:20| Show InChI InChI=1S/C30H47NO2/c1-19(2)20-11-16-30(25(32)31-33)18-17-28(6)21(24(20)30)9-10-23-27(5)14-8-13-26(3,4)22(27)12-15-29(23,28)7/h8,13,20-24,33H,1,9-12,14-18H2,2-7H3,(H,31,32)/t20-,21?,22-,23+,24-,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529637
(CHEMBL4592450)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@@]2([H])[C@@]1(C)CC[C@]1([H])[C@]2(C)CCC(=O)OC1(C)C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H47NO4/c1-25(2)14-16-30(24(33)31-34)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(32)35-26(3,4)21(27)10-13-29(22,28)7/h8,20-22,34H,9-18H2,1-7H3,(H,31,33)/t20-,21-,22+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529635
(CHEMBL4519581)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC\C(=N/O)C(C)(C)[C@]3([H])CC[C@@]12C)C(=O)NO |r,t:15| Show InChI InChI=1S/C30H48N2O3/c1-25(2)14-16-30(24(33)32-35)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31-34)26(3,4)21(27)10-13-29(22,28)7/h8,20-22,34-35H,9-18H2,1-7H3,(H,32,33)/b31-23+/t20-,21-,22+,27-,28+,29+,30-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529624
(CHEMBL4473530)Show SMILES [H][C@@]12[C@@H](CC[C@@]1(CC[C@]1(C)C2CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C |r| Show InChI InChI=1S/C36H56O6/c1-21(2)22-12-17-36(30(40)41)19-18-34(8)23(28(22)36)10-11-25-33(7)15-14-26(42-27(37)20-31(3,4)29(38)39)32(5,6)24(33)13-16-35(25,34)9/h22-26,28H,1,10-20H2,2-9H3,(H,38,39)(H,40,41)/t22-,23?,24-,25+,26-,28-,33-,34+,35+,36-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
Egl nine homolog 1/Prolyl hydroxylase EGLN2/Prolyl hydroxylase EGLN3/Transmembrane prolyl 4-hydroxylase
(Homo sapiens (Human)) | BDBM50529623
(CHEMBL4460360)Show SMILES [H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)C2=CC(=O)[C@@]2([H])[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)C(=O)OC |r,c:33,t:15| Show InChI InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-30(6)20(21(32)17-27)15-22(34)24-29(5)16-19(18-33)25(35)28(3,4)23(29)9-10-31(24,30)7/h15-16,21,23-24H,9-14,17H2,1-8H3/t21-,23-,24+,29-,30+,31+,32-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale
Curated by ChEMBL
| Assay Description
Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft... |
J Nat Prod 81: 2235-2243 (2018)
Article DOI: 10.1021/acs.jnatprod.8b00514
BindingDB Entry DOI: 10.7270/Q2QZ2FD9 |
More data for this
Ligand-Target Pair | |
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