Compile Data Set for Download or QSAR

Found 76 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 8'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50591324 (CHEMBL5185273) Show SMILES CN1CC[C@H](C1)Oc1ccc(F)c(-c2nc3c(o2)C(=O)c2ccccc2C3=O)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50591322 (CHEMBL5196686) Show SMILES CN1CC[C@H](C1)Oc1ccc(Cl)c(c1)-c1nc2c(o1)C(=O)c1ccccc1C2=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50591323 (CHEMBL5173239) Show SMILES CN1CC[C@H](C1)Oc1ccc(Cl)c(-c2nc3c(o2)C(=O)c2ccccc2C3=O)c1F |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50591321 (CHEMBL5172138) Show SMILES O=C1c2nc(oc2C(=O)c2ccccc12)-c1cccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00408 BindingDB Entry DOI: 10.7270/Q25H7M81
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50436151 (CHEMBL2398212) Show SMILES Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N Show InChI InChI=1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50436151 (CHEMBL2398212) Show SMILES Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N Show InChI InChI=1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Progenra, Inc. Curated by ChEMBL					Assay Description Inhibition of human full-length His-tagged USP8 expressed baculovirus infected insect cells using Ub-AMC as substrate by fluorescence spectroscopic a...				J Med Chem 61: 422-443 (2018) Article DOI: 10.1021/acs.jmedchem.7b00498 BindingDB Entry DOI: 10.7270/Q2CR5WVG
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50069768 (CHEMBL3407548) Show SMILES Clc1ccc2C(=O)c3nc(C#N)c(nc3-c2c1)C#N Show InChI InChI=1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)11-12(13(7)19)18-10(5-16)9(4-15)17-11/h1-3H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608392 (CHEMBL5281075) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608392 (CHEMBL5281075) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597448 (CHEMBL5180195) Show SMILES CCO\N=C1\c2ccccc2-c2nc(C#N)c(nc12)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597449 (CHEMBL5170305) Show SMILES O=C1c2ccccc2-c2cc(C#N)c(cc12)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608385 (CHEMBL4569978) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608385 (CHEMBL4569978) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608394 (CHEMBL5269711) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597451 (CHEMBL5202404) Show SMILES C=CCO\N=C1/c2ccccc2-c2nc(C#N)c(nc12)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608389 (CHEMBL5276040) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608391 (CHEMBL4515695) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597450 (CHEMBL5208383) Show SMILES N#Cc1nc2\C(=N\OCc3ccccc3)c3ccccc3-c2nc1C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608390 (CHEMBL4584162) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608544 (CHEMBL3392741) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50436151 (CHEMBL2398212) Show SMILES Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N Show InChI InChI=1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597468 (CHEMBL5184337) Show SMILES Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CC1)c1ccccn1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597448 (CHEMBL5180195) Show SMILES CCO\N=C1\c2ccccc2-c2nc(C#N)c(nc12)C#N Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608393 (CHEMBL4580655) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597463 (CHEMBL5176518) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CC1)C=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608387 (CHEMBL4550273) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597452 (CHEMBL5171659) Show SMILES COc1ccc(N2CCN(CC2)C(=S)Nc2ccc(cc2)[N+]([O-])=O)c(N)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608388 (CHEMBL5272836) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597469 (CHEMBL5197403) Show SMILES Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CC1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608386 (CHEMBL4442330) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597467 (CHEMBL5206972) Show SMILES Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CC1)C(=O)c1ccco1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608395 (CHEMBL5282532) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50538571 (CHEMBL4635160) Show SMILES C[C@H]1CNCC[C@H]1Oc1c(C)cc(Cl)cc1-c1ccnc2cc(CN3C(=O)C4C(C3=O)C4(C)C)sc12 |r| Show InChI InChI=1S/C28H30ClN3O3S/c1-14-9-16(29)10-19(24(14)35-21-6-7-30-12-15(21)2)18-5-8-31-20-11-17(36-25(18)20)13-32-26(33)22-23(27(32)34)28(22,3)4/h5,8-11,15,21-23,30H,6-7,12-13H2,1-4H3/t15-,21+,22?,23?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human USP8 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine u...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50548233 (CHEMBL4756029) Show SMILES CC(C)(C)NS(=O)(=O)c1cccc2c(NC(=O)C(Cc3ccccc3)NC(=O)c3ccccc3)cccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of USP8 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608384 (CHEMBL5276519) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608384 (CHEMBL5276519) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597465 (CHEMBL5205340) Show SMILES CCN1CCN(CC1)c1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(Oc3c(C)n[nH]c3C)c2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597455 (CHEMBL5206674) Show SMILES Oc1cc(O)c2c(oc(cc2=O)-c2ccc(cc2)N2CCCNCC2)c1OC1CCCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597457 (CHEMBL4469440) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597464 (CHEMBL5181521) Show SMILES CC(C)N1CCN(CC1)c1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(Oc3c(C)n[nH]c3C)c2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597462 (CHEMBL4536844) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(C)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597456 (CHEMBL5198716) Show SMILES Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCCNCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597458 (CHEMBL4591454) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCOCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597466 (CHEMBL5170419) Show SMILES Cc1n[nH]c(C)c1Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCN(CCO)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597454 (CHEMBL5175647) Show SMILES CC(C)Oc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCCNCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608396 (CHEMBL4438288) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50608396 (CHEMBL4438288) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597453 (CHEMBL4567355) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCCNCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50436152 (SPONGIACIDIN C) Show SMILES O=C1NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]ccc12 Show InChI InChI=1S/C11H10N4O3/c16-9-7-5(1-3-12-7)6(2-4-13-9)8-10(17)15-11(18)14-8/h1,3,12H,2,4H2,(H,13,16)(H2,14,15,17,18)/b8-6-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of core catalytic domain of USP8 (unknown origin) using ubiquitin-Rh110 as substrate				Bioorg Med Chem Lett 23: 3884-6 (2013) Article DOI: 10.1016/j.bmcl.2013.04.066 BindingDB Entry DOI: 10.7270/Q29P332K
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 8 (Homo sapiens (Human))	BDBM50597459 (CHEMBL5170083) Show SMILES COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(cc1)N1CCC(O)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00013 BindingDB Entry DOI: 10.7270/Q2ST7TW8
					More data for this Ligand-Target Pair

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