Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal alpha-glucosidase/Maltase-glucoamylase/Probable maltase-glucoamylase 2/Sucrase-isomaltase, intestinal (Homo sapiens (Human)) | BDBM23406 ((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-NPG as substrate pretreated for 10 mins followed by substrate addition measured after 5 mins | J Nat Prod 80: 2923-2929 (2017) Article DOI: 10.1021/acs.jnatprod.7b00457 BindingDB Entry DOI: 10.7270/Q2CJ8H0S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |