Compile Data Set for Download or QSAR

Found 285 hits Enz. Inhib. hit(s) with Target = 'VHL complex'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VHL complex (Homo sapiens (Human))	BDBM454848 (US10730870, Example 11 | US11512083, Example 11) Show SMILES CC(C)[C@H](N1Cc2ccc(Br)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31BrN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	16.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454972 (US10730870, Example 141 | US11512083, Example 141) Show SMILES CC(C)C(C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)c1cc(C)no1 |r| Show InChI InChI=1S/C25H30N4O4S/c1-14(2)22(21-9-15(3)28-33-21)25(32)29-12-19(30)10-20(29)24(31)26-11-17-5-7-18(8-6-17)23-16(4)27-13-34-23/h5-9,13-14,19-20,22,30H,10-12H2,1-4H3,(H,26,31)/t19-,20+,22?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	70.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454969 (US10730870, Example 138 | US10730870, Example 145 ...) Show SMILES CC(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)c1cc(C)no1 |r| Show InChI InChI=1S/C25H30N4O4S/c1-14(2)22(21-9-15(3)28-33-21)25(32)29-12-19(30)10-20(29)24(31)26-11-17-5-7-18(8-6-17)23-16(4)27-13-34-23/h5-9,13-14,19-20,22,30H,10-12H2,1-4H3,(H,26,31)/t19-,20+,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454909 (US10730870, Example 76 | US11512083, Example 76) Show SMILES COc1ccc(CCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C32H40N4O5S/c1-20-28(42-19-34-20)23-11-6-22(7-12-23)17-33-30(39)26-16-24(37)18-36(26)31(40)29(32(2,3)4)35-27(38)15-10-21-8-13-25(41-5)14-9-21/h6-9,11-14,19,24,26,29,37H,10,15-18H2,1-5H3,(H,33,39)(H,35,38)/t24-,26+,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454884 (US10730870, Example 47 | US11512083, Example 47) Show SMILES CC(C)[C@H](N1Cc2cccc(C#N)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-6-4-5-21(12-31)25(22)29(35)38)30(39)34-15-23(36)11-24(34)28(37)32-13-19-7-9-20(10-8-19)27-18(3)33-16-40-27/h4-10,16-17,23-24,26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,24+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454907 (US10730870, Example 74 | US11512083, Example 74) Show SMILES CC(C)[C@H](N1Cc2ccc(Cl)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31ClN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454853 (US10730870, Example 16 | US11512083, Example 16) Show SMILES CC(C)[C@H](N1Cc2cc(F)ccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31FN4O4S/c1-16(2)25(34-13-20-10-21(30)8-9-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454897 (US10730870, Example 60 | US11512083, Example 60) Show SMILES CC(C)CCC(=O)N[C@H](CSSC[C@H](NC(=O)CCC(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(=O)N1C[C@@H](O)C[C@@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C50H66N8O8S4/c1-29(2)7-17-43(61)55-39(49(65)57-23-37(59)19-41(57)47(63)51-21-33-9-13-35(14-10-33)45-31(5)53-27-67-45)25-69-70-26-40(56-44(62)18-8-30(3)4)50(66)58-24-38(60)20-42(58)48(64)52-22-34-11-15-36(16-12-34)46-32(6)54-28-68-46/h9-16,27-30,37-42,59-60H,7-8,17-26H2,1-6H3,(H,51,63)(H,52,64)(H,55,61)(H,56,62)/t37-,38+,39+,40-,41+,42-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454846 (US10730870, Example 9 | US11512083, Example 9) Show SMILES CC(C)[C@H](N1Cc2ccc(F)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31FN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454854 (US10730870, Example 17 | US11512083, Example 17) Show SMILES CC(C)[C@H](N1Cc2ccc(cc2C1=O)C#N)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-9-6-20(12-31)10-24(22)29(35)38)30(39)34-15-23(36)11-25(34)28(37)32-13-19-4-7-21(8-5-19)27-18(3)33-16-40-27/h4-10,16-17,23,25-26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	317	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454916 (US10730870, Example 83 | US11512083, Example 83) Show SMILES COc1ccccc1CCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C32H40N4O5S/c1-20-28(42-19-34-20)23-12-10-21(11-13-23)17-33-30(39)25-16-24(37)18-36(25)31(40)29(32(2,3)4)35-27(38)15-14-22-8-6-7-9-26(22)41-5/h6-13,19,24-25,29,37H,14-18H2,1-5H3,(H,33,39)(H,35,38)/t24-,25+,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454884 (US10730870, Example 47 | US11512083, Example 47) Show SMILES CC(C)[C@H](N1Cc2cccc(C#N)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-6-4-5-21(12-31)25(22)29(35)38)30(39)34-15-23(36)11-24(34)28(37)32-13-19-7-9-20(10-8-19)27-18(3)33-16-40-27/h4-10,16-17,23-24,26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,24+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454910 (US10730870, Example 77 | US11512083, Example 77) Show SMILES COc1cccc(CCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)c1 |r| Show InChI InChI=1S/C32H40N4O5S/c1-20-28(42-19-34-20)23-12-9-22(10-13-23)17-33-30(39)26-16-24(37)18-36(26)31(40)29(32(2,3)4)35-27(38)14-11-21-7-6-8-25(15-21)41-5/h6-10,12-13,15,19,24,26,29,37H,11,14,16-18H2,1-5H3,(H,33,39)(H,35,38)/t24-,26+,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454881 (US10730870, Example 44 | US11512083, Example 44) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCc2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C31H38N4O4S/c1-20-27(40-19-33-20)23-13-10-22(11-14-23)17-32-29(38)25-16-24(36)18-35(25)30(39)28(31(2,3)4)34-26(37)15-12-21-8-6-5-7-9-21/h5-11,13-14,19,24-25,28,36H,12,15-18H2,1-4H3,(H,32,38)(H,34,37)/t24-,25+,28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454858 (US10730870, Example 21 | US11512083, Example 21) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)Cc2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C30H36N4O4S/c1-19-26(39-18-32-19)22-12-10-21(11-13-22)16-31-28(37)24-15-23(35)17-34(24)29(38)27(30(2,3)4)33-25(36)14-20-8-6-5-7-9-20/h5-13,18,23-24,27,35H,14-17H2,1-4H3,(H,31,37)(H,33,36)/t23-,24+,27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454932 (US10730870, Example 99 | US11512083, Example 99) Show SMILES CC(C)[C@H](N1Cc2ncccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C28H31N5O4S/c1-16(2)24(33-14-22-21(27(33)36)5-4-10-29-22)28(37)32-13-20(34)11-23(32)26(35)30-12-18-6-8-19(9-7-18)25-17(3)31-15-38-25/h4-10,15-16,20,23-24,34H,11-14H2,1-3H3,(H,30,35)/t20-,23+,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454863 (US10730870, Example 26 | US11512083, Example 26) Show SMILES CC(C)[C@H](N1Cc2c(cccc2Br)C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31BrN4O4S/c1-16(2)25(34-14-22-21(28(34)37)5-4-6-23(22)30)29(38)33-13-20(35)11-24(33)27(36)31-12-18-7-9-19(10-8-18)26-17(3)32-15-39-26/h4-10,15-16,20,24-25,35H,11-14H2,1-3H3,(H,31,36)/t20-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	441	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454907 (US10730870, Example 74 | US11512083, Example 74) Show SMILES CC(C)[C@H](N1Cc2ccc(Cl)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31ClN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454881 (US10730870, Example 44 | US11512083, Example 44) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCc2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C31H38N4O4S/c1-20-27(40-19-33-20)23-13-10-22(11-14-23)17-32-29(38)25-16-24(36)18-35(25)30(39)28(31(2,3)4)34-26(37)15-12-21-8-6-5-7-9-21/h5-11,13-14,19,24-25,28,36H,12,15-18H2,1-4H3,(H,32,38)(H,34,37)/t24-,25+,28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	465	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454890 (US10730870, Example 53 | US11512083, Example 53) Show SMILES COCC#Cc1ccc2C(=O)N(Cc2c1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C33H36N4O5S/c1-20(2)29(37-17-25-14-22(6-5-13-42-4)9-12-27(25)32(37)40)33(41)36-18-26(38)15-28(36)31(39)34-16-23-7-10-24(11-8-23)30-21(3)35-19-43-30/h7-12,14,19-20,26,28-29,38H,13,15-18H2,1-4H3,(H,34,39)/t26-,28+,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	474	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454846 (US10730870, Example 9 | US11512083, Example 9) Show SMILES CC(C)[C@H](N1Cc2ccc(F)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31FN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	498	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454872 (US10730870, Example 35 | US11512083, Example 35) Show SMILES CC(C)[C@H](N1Cc2c(cccc2C#N)C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-15-24-21(12-31)5-4-6-23(24)29(35)38)30(39)34-14-22(36)11-25(34)28(37)32-13-19-7-9-20(10-8-19)27-18(3)33-16-40-27/h4-10,16-17,22,25-26,36H,11,13-15H2,1-3H3,(H,32,37)/t22-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	509	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454839 (US10730870, Example 2 | US11512083, Example 2) Show SMILES CC(C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C1CC1 |r| Show InChI InChI=1S/C31H34N4O4S/c1-18(2)27(35-15-22-5-3-4-6-24(22)30(35)38)31(39)34-16-23(36)13-25(34)29(37)32-14-19-7-9-21(10-8-19)28-26(20-11-12-20)33-17-40-28/h3-10,17-18,20,23,25,27,36H,11-16H2,1-2H3,(H,32,37)/t23-,25+,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454870 (US10730870, Example 33 | US11512083, Example 33) Show SMILES CC(C)[C@H](N1Cc2c(cccc2F)C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31FN4O4S/c1-16(2)25(34-14-22-21(28(34)37)5-4-6-23(22)30)29(38)33-13-20(35)11-24(33)27(36)31-12-18-7-9-19(10-8-18)26-17(3)32-15-39-26/h4-10,15-16,20,24-25,35H,11-14H2,1-3H3,(H,31,36)/t20-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	539	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454848 (US10730870, Example 11 | US11512083, Example 11) Show SMILES CC(C)[C@H](N1Cc2ccc(Br)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31BrN4O4S/c1-16(2)25(34-13-20-8-9-21(30)10-23(20)28(34)37)29(38)33-14-22(35)11-24(33)27(36)31-12-18-4-6-19(7-5-18)26-17(3)32-15-39-26/h4-10,15-16,22,24-25,35H,11-14H2,1-3H3,(H,31,36)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	542	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454910 (US10730870, Example 77 | US11512083, Example 77) Show SMILES COc1cccc(CCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)c1 |r| Show InChI InChI=1S/C32H40N4O5S/c1-20-28(42-19-34-20)23-12-9-22(10-13-23)17-33-30(39)26-16-24(37)18-36(26)31(40)29(32(2,3)4)35-27(38)14-11-21-7-6-8-25(15-21)41-5/h6-10,12-13,15,19,24,26,29,37H,11,14,16-18H2,1-5H3,(H,33,39)(H,35,38)/t24-,26+,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454927 (US10730870, Example 94 | US11512083, Example 94) Show SMILES CC[C@H](C)[C@H](N1Cc2ccc(F)cc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H33FN4O4S/c1-4-17(2)26(35-14-21-9-10-22(31)11-24(21)29(35)38)30(39)34-15-23(36)12-25(34)28(37)32-13-19-5-7-20(8-6-19)27-18(3)33-16-40-27/h5-11,16-17,23,25-26,36H,4,12-15H2,1-3H3,(H,32,37)/t17-,23+,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454867 (US10730870, Example 30 | US11512083, Example 30) Show SMILES CC[C@H](C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H34N4O4S/c1-4-18(2)26(34-15-22-7-5-6-8-24(22)29(34)37)30(38)33-16-23(35)13-25(33)28(36)31-14-20-9-11-21(12-10-20)27-19(3)32-17-39-27/h5-12,17-18,23,25-26,35H,4,13-16H2,1-3H3,(H,31,36)/t18-,23+,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	572	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454900 (US10730870, Example 65 | US11512083, Example 65) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N2Cc3ccccc3C2=O)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C30H34N4O4S/c1-18-25(39-17-32-18)20-11-9-19(10-12-20)14-31-27(36)24-13-22(35)16-33(24)29(38)26(30(2,3)4)34-15-21-7-5-6-8-23(21)28(34)37/h5-12,17,22,24,26,35H,13-16H2,1-4H3,(H,31,36)/t22-,24+,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	578	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454845 (US10730870, Example 8 | US11512083, Example 8) Show SMILES CC(C)[C@H](N1Cc2cccc(F)c2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31FN4O4S/c1-16(2)25(34-13-20-5-4-6-22(30)24(20)28(34)37)29(38)33-14-21(35)11-23(33)27(36)31-12-18-7-9-19(10-8-18)26-17(3)32-15-39-26/h4-10,15-16,21,23,25,35H,11-14H2,1-3H3,(H,31,36)/t21-,23+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454916 (US10730870, Example 83 | US11512083, Example 83) Show SMILES COc1ccccc1CCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C32H40N4O5S/c1-20-28(42-19-34-20)23-12-10-21(11-13-23)17-33-30(39)25-16-24(37)18-36(25)31(40)29(32(2,3)4)35-27(38)15-14-22-8-6-7-9-26(22)41-5/h6-13,19,24-25,29,37H,14-18H2,1-5H3,(H,33,39)(H,35,38)/t24-,25+,29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	626	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454900 (US10730870, Example 65 | US11512083, Example 65) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N2Cc3ccccc3C2=O)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C30H34N4O4S/c1-18-25(39-17-32-18)20-11-9-19(10-12-20)14-31-27(36)24-13-22(35)16-33(24)29(38)26(30(2,3)4)34-15-21-7-5-6-8-23(21)28(34)37/h5-12,17,22,24,26,35H,13-16H2,1-4H3,(H,31,36)/t22-,24+,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454871 (US10730870, Example 34 | US11512083, Example 34) Show SMILES CC(C)[C@H](N1Cc2cc(ccc2C1=O)C#N)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H31N5O4S/c1-17(2)26(35-14-22-10-20(12-31)6-9-24(22)29(35)38)30(39)34-15-23(36)11-25(34)28(37)32-13-19-4-7-21(8-5-19)27-18(3)33-16-40-27/h4-10,16-17,23,25-26,36H,11,13-15H2,1-3H3,(H,32,37)/t23-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454901 (US10730870, Example 68 | US11512083, Example 68) Show SMILES CC(C)[C@H](N1Cc2c(cccc2Cl)C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H31ClN4O4S/c1-16(2)25(34-14-22-21(28(34)37)5-4-6-23(22)30)29(38)33-13-20(35)11-24(33)27(36)31-12-18-7-9-19(10-8-18)26-17(3)32-15-39-26/h4-10,15-16,20,24-25,35H,11-14H2,1-3H3,(H,31,36)/t20-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	668	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM50099062 (CHEMBL3344081 | US10730870, Example 3 | US11512083...) Show SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C24H32N4O4S/c1-14-20(33-13-26-14)17-8-6-16(7-9-17)11-25-22(31)19-10-18(30)12-28(19)23(32)21(24(3,4)5)27-15(2)29/h6-9,13,18-19,21,30H,10-12H2,1-5H3,(H,25,31)(H,27,29)/t18-,19+,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	696	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair				3D Structure (crystal)
VHL complex (Homo sapiens (Human))	BDBM454843 (US10730870, Example 110 | US10730870, Example 6 | ...) Show SMILES CC(C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C29H32N4O4S/c1-17(2)25(33-14-21-6-4-5-7-23(21)28(33)36)29(37)32-15-22(34)12-24(32)27(35)30-13-19-8-10-20(11-9-19)26-18(3)31-16-38-26/h4-11,16-17,22,24-25,34H,12-15H2,1-3H3,(H,30,35)/t22-,24+,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	697	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454876 (US10730870, Example 39 | US11512083, Example 39) Show SMILES CC(C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H34N4O4S/c1-17(2)26(34-14-22-7-5-6-8-24(22)29(34)37)30(38)33-15-23(35)13-25(33)28(36)32-18(3)20-9-11-21(12-10-20)27-19(4)31-16-39-27/h5-12,16-18,23,25-26,35H,13-15H2,1-4H3,(H,32,36)/t18-,23+,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	699	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454894 (US10730870, Example 57 | US11512083, Example 57) Show SMILES COCCCc1ccc2C(=O)N(Cc2c1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C33H40N4O5S/c1-20(2)29(37-17-25-14-22(6-5-13-42-4)9-12-27(25)32(37)40)33(41)36-18-26(38)15-28(36)31(39)34-16-23-7-10-24(11-8-23)30-21(3)35-19-43-30/h7-12,14,19-20,26,28-29,38H,5-6,13,15-18H2,1-4H3,(H,34,39)/t26-,28+,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	717	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454839 (US10730870, Example 2 | US11512083, Example 2) Show SMILES CC(C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C1CC1 |r| Show InChI InChI=1S/C31H34N4O4S/c1-18(2)27(35-15-22-5-3-4-6-24(22)30(35)38)31(39)34-16-23(36)13-25(34)29(37)32-14-19-7-9-21(10-8-19)28-26(20-11-12-20)33-17-40-28/h3-10,17-18,20,23,25,27,36H,11-16H2,1-2H3,(H,32,37)/t23-,25+,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	732	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454875 (US10730870, Example 38 | US11512083, Example 38) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C2CCCC2)N2Cc3ccccc3C2=O)cc1 |r| Show InChI InChI=1S/C31H34N4O4S/c1-19-28(40-18-33-19)22-12-10-20(11-13-22)15-32-29(37)26-14-24(36)17-34(26)31(39)27(21-6-2-3-7-21)35-16-23-8-4-5-9-25(23)30(35)38/h4-5,8-13,18,21,24,26-27,36H,2-3,6-7,14-17H2,1H3,(H,32,37)/t24-,26+,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	758	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454842 (US10730870, Example 5 | US11512083, Example 5) Show SMILES CCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)cc1 |r| Show InChI InChI=1S/C30H34N4O4S/c1-4-24-27(39-17-32-24)20-11-9-19(10-12-20)14-31-28(36)25-13-22(35)16-33(25)30(38)26(18(2)3)34-15-21-7-5-6-8-23(21)29(34)37/h5-12,17-18,22,25-26,35H,4,13-16H2,1-3H3,(H,31,36)/t22-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	799	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454911 (US10730870, Example 78 | US11512083, Example 78) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccn2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C28H33N5O4S/c1-17-23(38-16-31-17)19-10-8-18(9-11-19)14-30-26(36)22-13-20(34)15-33(22)27(37)24(28(2,3)4)32-25(35)21-7-5-6-12-29-21/h5-12,16,20,22,24,34H,13-15H2,1-4H3,(H,30,36)(H,32,35)/t20-,22+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454891 (US10730870, Example 54 | US11512083, Example 54) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)C2(CCCCC2)N2Cc3ccccc3C2=O)cc1 |r| Show InChI InChI=1S/C31H34N4O4S/c1-20-27(40-19-33-20)22-11-9-21(10-12-22)16-32-28(37)26-15-24(36)18-34(26)30(39)31(13-5-2-6-14-31)35-17-23-7-3-4-8-25(23)29(35)38/h3-4,7-12,19,24,26,36H,2,5-6,13-18H2,1H3,(H,32,37)/t24-,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	834	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454855 (US10730870, Example 18 | US11512083, Example 18) Show SMILES CC(C)CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C27H38N4O4S/c1-16(2)11-22(33)30-24(27(4,5)6)26(35)31-14-20(32)12-21(31)25(34)28-13-18-7-9-19(10-8-18)23-17(3)29-15-36-23/h7-10,15-16,20-21,24,32H,11-14H2,1-6H3,(H,28,34)(H,30,33)/t20-,21+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	855	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454867 (US10730870, Example 30 | US11512083, Example 30) Show SMILES CC[C@H](C)[C@H](N1Cc2ccccc2C1=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H34N4O4S/c1-4-18(2)26(34-15-22-7-5-6-8-24(22)29(34)37)30(38)33-16-23(35)13-25(33)28(36)31-14-20-9-11-21(12-10-20)27-19(3)32-17-39-27/h5-12,17-18,23,25-26,35H,4,13-16H2,1-3H3,(H,31,36)/t18-,23+,25-,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	859	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454944 (US10730870, Example 111 | US11512083, Example 111) Show SMILES COC1=CC(=O)N(C1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r,t:2| Show InChI InChI=1S/C26H32N4O5S/c1-15(2)23(30-13-20(35-4)10-22(30)32)26(34)29-12-19(31)9-21(29)25(33)27-11-17-5-7-18(8-6-17)24-16(3)28-14-36-24/h5-8,10,14-15,19,21,23,31H,9,11-13H2,1-4H3,(H,27,33)/t19-,21+,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	859	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454905 (US10730870, Example 72 | US11512083, Example 72) Show SMILES COc1ccc2C(=O)N(Cc2c1)[C@@H](C(C)C)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H34N4O5S/c1-17(2)26(34-14-21-11-23(39-4)9-10-24(21)29(34)37)30(38)33-15-22(35)12-25(33)28(36)31-13-19-5-7-20(8-6-19)27-18(3)32-16-40-27/h5-11,16-17,22,25-26,35H,12-15H2,1-4H3,(H,31,36)/t22-,25+,26+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454893 (US10730870, Example 56 | US11512083, Example 56) Show SMILES CC(C)CCC(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C30H42N4O4S/c1-19(2)9-14-26(36)33-27(22-7-5-4-6-8-22)30(38)34-17-24(35)15-25(34)29(37)31-16-21-10-12-23(13-11-21)28-20(3)32-18-39-28/h10-13,18-19,22,24-25,27,35H,4-9,14-17H2,1-3H3,(H,31,37)(H,33,36)/t24-,25+,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	878	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454866 (US10730870, Example 29 | US11512083, Example 29) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccccc2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C29H34N4O4S/c1-18-24(38-17-31-18)20-12-10-19(11-13-20)15-30-27(36)23-14-22(34)16-33(23)28(37)25(29(2,3)4)32-26(35)21-8-6-5-7-9-21/h5-13,17,22-23,25,34H,14-16H2,1-4H3,(H,30,36)(H,32,35)/t22-,23+,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	905	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair
VHL complex (Homo sapiens (Human))	BDBM454880 (US10730870, Example 43 | US11512083, Example 43) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccc(cc2)C#N)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C30H33N5O4S/c1-18-25(40-17-33-18)21-9-7-20(8-10-21)15-32-28(38)24-13-23(36)16-35(24)29(39)26(30(2,3)4)34-27(37)22-11-5-19(14-31)6-12-22/h5-12,17,23-24,26,36H,13,15-16H2,1-4H3,(H,32,38)(H,34,37)/t23-,24+,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	906	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability of VHL ligands to compete for the HIF 1 a binding site on VCB was determined through a fluorescence polarization competition assay as describ...				Citation and Details BindingDB Entry DOI: 10.7270/Q20K2DC4
					More data for this Ligand-Target Pair

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