Cell (A) | Syringe (B) | Cell Links | Syringe Links | Cell + Syr Links | ΔG° kcal/mole | -TΔS° kcal/mole | ΔH° kcal/mole | log K | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -14.4 | -10.7 | -3.69 | 10.5 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease B Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -14.4 | -10.7 | -3.69 | 10.5 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -13.7 | -9.39 | -4.29 | 10 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | HIV-1 Protease (Human immunodeficiency virus type 1) | MMDB PC cid PC sid PDB | GoogleScholar PDB | -13.5 | -11.2 | -2.30 | n/a | 5 | 25 | |
The Johns Hopkins University | Biochemistry 39: 11876-83 (2000) | |||||||||
HIV-1 Protease C Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -13.4 | -10.3 | -3.09 | 9.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease A Subtype (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -13.2 | -10.3 | -2.90 | 9.65 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease Mutant (L10I/L90M) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -12.9 | -10.1 | -2.80 | 9.43 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
HIV-1 Protease Mutant (M46I/I54V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -12.8 | -13.7 | 0.899 | 9.36 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
HIV-1 Protease Mutant, A-1 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -12.0 | -12.0 | 0.0200 | 8.80 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant (V82A/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -11.9 | -8.29 | -3.59 | 8.70 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
HIV-1 Protease B Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -10.9 | -10.2 | -0.699 | 7.95 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease Mutant, MDR-QM (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -10.7 | -14.0 | 3.29 | 7.87 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | HIV-1 Protease Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | MMDB PC cid PC sid PDB | GoogleScholar PDB | -9.98 | -10.5 | 0.499 | n/a | 5 | 25 | |
The Johns Hopkins University | Biochemistry 39: 11876-83 (2000) | |||||||||
HIV-1 Protease C Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -9.78 | -8.69 | -1.10 | 7.21 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease A Subtype Mutant (V82F/I84V) (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -9.68 | -8.49 | -1.20 | 7.08 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 41: 8613-9 (2002) | |||||||||
HIV-1 Protease Mutant, MDR-HM (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar PDB | MMDB PC cid PC sid PDB | -9.28 | -12.2 | 2.90 | 6.83 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 13659-66 (2003) | |||||||||
HIV-1 Protease Mutant, NAM-10 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -8.79 | -6.49 | -2.30 | 6.43 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) | |||||||||
HIV-1 Protease Mutant, ANAM-11 (Human immunodeficiency virus type 1) | BDBM520 (1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...) | GoogleScholar | MMDB PC cid PC sid PDB | -7.69 | -1.40 | -6.29 | 5.64 | 5 | 25 | |
The Johns Hopkins University | Biochemistry 42: 631-8 (2003) |