Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Agonist activity at 6his-tagged ERRalpha LBD assessed as recruitment of GST-labeled coactivator Scr2 by TR-FRET assay | J Med Chem 54: 788-808 (2012) Article DOI: 10.1021/jm101063h BindingDB Entry DOI: 10.7270/Q208668Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50336730 (4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | MMDB Article PubMed | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Agonist activity at 6his-tagged ERRalpha LBD assessed as recruitment of GST-labeled coactivator Scr2 by TR-FRET assay | J Med Chem 54: 788-808 (2012) Article DOI: 10.1021/jm101063h BindingDB Entry DOI: 10.7270/Q208668Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50336763 (4-(5-(2,5-dimethylphenyl)-1-methyl-1H-pyrazol-3-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Antagonist activity at ERRalpha LBD expressed in HEK293 cells assessed as Gal4-SRC2 interaction by two hybrid luciferase reporter gene assay | J Med Chem 54: 788-808 (2012) Article DOI: 10.1021/jm101063h BindingDB Entry DOI: 10.7270/Q208668Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557790 (CHEMBL4789350) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557786 (CHEMBL4776913) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557798 (CHEMBL4760865) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557797 (CHEMBL4798460) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557794 (CHEMBL4742675) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557795 (CHEMBL4756874) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557796 (CHEMBL4783029) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557792 (CHEMBL4794502) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557789 (CHEMBL4790878) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557787 (CHEMBL4789973) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR1 (Homo sapiens (Human)) | BDBM50557793 (CHEMBL4744735) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at recombinant full-length human ERRalpha expressed in MG63 cells assessed as transcriptional activation incubated for 18 hrs by dua... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00100 BindingDB Entry DOI: 10.7270/Q25H7KZK | |||||||||||
More data for this Ligand-Target Pair |