Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264613 (US9718760, C157) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.44E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264597 (US9718760, C152) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264614 (US9718760, C158) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.47E+5 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264648 (US9718760, C161) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.67E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264598 (US9718760, C155) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.33E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Antithrombin-III/Prothrombin (Homo sapiens (Human)) | BDBM264627 (US9718760, C160) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.33E+6 | n/a | n/a | n/a | n/a | n/a | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph... | US Patent US9718760 (2017) BindingDB Entry DOI: 10.7270/Q2K939HK | |||||||||||
More data for this Ligand-Target Pair |