BindingDB PrimarySearch

Found 9 hits of ic50 for UniProtKB: Q82122
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Genome polyprotein (Human rhinovirus 16)	BDBM521557 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
TBA					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50208940 (5-bromo-pyridin-3-yl furan-2-carboxylate \| 5-bromo...) Show SMILES Brc1cncc(OC(=O)c2ccco2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay				Bioorg Med Chem Lett 19: 3632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.114 BindingDB Entry DOI: 10.7270/Q2542NHW
Institute of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM521555 (((2S,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
TBA					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50268736 (2-oxo-1,2-dihydroquinolin-4-yl furan-2-carboxylate...) Show SMILES O=C(Oc1cc(=O)[nH]c2ccccc12)c1ccco1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay				Bioorg Med Chem Lett 19: 3632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.114 BindingDB Entry DOI: 10.7270/Q2542NHW
Institute of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM521556 (((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
TBA					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50236025 (CHEMBL2016761 \| US11149049, No. C2) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...				Citation and Details BindingDB Entry DOI: 10.7270/Q28P63PG
TBA					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50261166 (5-Chloropyridin-3-yl 1H-imidazole-4-carboxylate \| ...) Show SMILES Clc1cncc(OC(=O)c2cnc[nH]2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay				Bioorg Med Chem Lett 19: 3632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.114 BindingDB Entry DOI: 10.7270/Q2542NHW
Institute of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50268882 (5-chloropyridin-3-yl 4-ethoxy-2-styryloxazole-5-ca...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay				Bioorg Med Chem Lett 19: 3632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.114 BindingDB Entry DOI: 10.7270/Q2542NHW
Institute of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus 16)	BDBM50261454 (5-Chloropyridin-3-yl 2-naphthoate \| CHEMBL466351) Show SMILES Clc1cncc(OC(=O)c2ccc3ccccc3c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of HRV-16 protease 3C expressed in Escherichia coli BL21(DE3) by FRET assay				Bioorg Med Chem Lett 19: 3632-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.114 BindingDB Entry DOI: 10.7270/Q2542NHW
Institute of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair