Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 11B (Homo sapiens (Human)) | BDBM50250180![]() (CHEMBL4101411) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
High Magnetic Field Laboratory, Chinese Academy of Sciences , Mailbox 1110, 350 Shushanhu Road, Hefei, Anhui 230031, P. R. China. Curated by ChEMBL | Assay Description Inhibition of human GST-tagged CDK11 by Z'Lyte assay | J Med Chem 60: 8407-8424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00840 BindingDB Entry DOI: 10.7270/Q2474D9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 11B (Homo sapiens (Human)) | BDBM7392![]() (2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant human CDK expressed in baculovirus infected sf9 cells after 10 mins by SDS-PAGE based autoradiography | J Nat Prod 80: 2178-2187 (2017) Article DOI: 10.1021/acs.jnatprod.7b00390 BindingDB Entry DOI: 10.7270/Q2WW7M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 11B (Homo sapiens (Human)) | BDBM50466210![]() (CHEMBL4281048) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged inactive state of human CDK11 | Eur J Med Chem 158: 896-916 (2018) Article DOI: 10.1016/j.ejmech.2018.09.025 BindingDB Entry DOI: 10.7270/Q2DJ5J9D | |||||||||||
More data for this Ligand-Target Pair |