Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359525 (CHEMBL1927146) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 365 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359522 (CHEMBL1927160) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 433 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359520 (CHEMBL1927158) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359527 (CHEMBL1927148) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 645 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359533 (CHEMBL1927154) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359521 (CHEMBL1927159) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359534 (CHEMBL1927155) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359519 (CHEMBL1927157) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359529 (CHEMBL1927150) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359528 (CHEMBL1927149) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359532 (CHEMBL1927153) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359530 (CHEMBL1927151) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359524 (CHEMBL1927145) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359523 (CHEMBL1927147) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359518 (CHEMBL1927156) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50330722 (2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex, S.A. Curated by ChEMBL | Assay Description Inhibition of human NOX2 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH | J Med Chem 53: 7715-30 (2010) Article DOI: 10.1021/jm100773e BindingDB Entry DOI: 10.7270/Q2KH0NKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359531 (CHEMBL1927152) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50359526 (CHEMBL1926690) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex S.A. Curated by ChEMBL | Assay Description Antagonist activity at human NOX2 in human polymorphonuclear cell membrane assessed as inhibition of ROS production after 20 mins by cell-free amplex... | Bioorg Med Chem 19: 6989-99 (2011) Article DOI: 10.1016/j.bmc.2011.10.016 BindingDB Entry DOI: 10.7270/Q2ZP46JC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome b-245 heavy chain (Homo sapiens (Human)) | BDBM50330688 (4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-1H-pyrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Genkyotex, S.A. Curated by ChEMBL | Assay Description Inhibition of human NOX2 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH | J Med Chem 53: 7715-30 (2010) Article DOI: 10.1021/jm100773e BindingDB Entry DOI: 10.7270/Q2KH0NKJ | |||||||||||
More data for this Ligand-Target Pair |