Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388931![]() (CHEMBL2063402) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50039492![]() (CHEMBL1231498) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysis | ACS Med Chem Lett 6: 216-20 (2015) Article DOI: 10.1021/ml500475n BindingDB Entry DOI: 10.7270/Q2VT1TTQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388933![]() (CHEMBL2063403) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50039493![]() (CHEMBL3357333) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska-Lincoln Curated by ChEMBL | Assay Description Inhibition of human recombinant HLCS using P67 as substrate after 2 hrs relative to vehicle-treated control | Bioorg Med Chem Lett 24: 5568-71 (2014) Article DOI: 10.1016/j.bmcl.2014.11.010 BindingDB Entry DOI: 10.7270/Q2W097KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388934![]() (CHEMBL2063404) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388927![]() (CHEMBL2063398) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 3.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388932![]() (CHEMBL2062535) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50039494![]() (CHEMBL3357334) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska-Lincoln Curated by ChEMBL | Assay Description Inhibition of human recombinant HLCS using P67 as substrate after 2 hrs relative to vehicle-treated control | Bioorg Med Chem Lett 24: 5568-71 (2014) Article DOI: 10.1016/j.bmcl.2014.11.010 BindingDB Entry DOI: 10.7270/Q2W097KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388935![]() (CHEMBL2063405) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201191![]() (CHEMBL3951442) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201194![]() (CHEMBL3932600) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201195![]() (CHEMBL3972792) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201196![]() (CHEMBL3961751) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201197![]() (CHEMBL3895686) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201198![]() (CHEMBL3968104) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201199![]() (CHEMBL3934430) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201200![]() (CHEMBL3905875) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201201![]() (CHEMBL3901708) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201202![]() (CHEMBL3971239) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201203![]() (CHEMBL3905724) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201204![]() (CHEMBL3927537) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201205![]() (CHEMBL3914706) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201206![]() (CHEMBL3960176) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201207![]() (CHEMBL3910734) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201208![]() (CHEMBL3892750) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201209![]() (CHEMBL3914868) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201210![]() (CHEMBL3933745) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201189![]() (CHEMBL3984675) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201190![]() (CHEMBL3942705) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201188![]() (CHEMBL3891635) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201192![]() (CHEMBL3932681) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201193![]() (CHEMBL3974372) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201186![]() (CHEMBL3923732) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50201187![]() (CHEMBL3976601) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of human biotin protein ligase assessed as reduction in 3H-biotin incorporation into pyruvate carboxylase biotin domain after 10 mins by l... | ACS Med Chem Lett 7: 1068-1072 (2016) Article DOI: 10.1021/acsmedchemlett.6b00248 BindingDB Entry DOI: 10.7270/Q2QV3PGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388928![]() (CHEMBL2063399) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388930![]() (CHEMBL2063401) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50388929![]() (CHEMBL2063400) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-biotin from human BPL after 20 mins by scintillation counting | ACS Med Chem Lett 3: 509-514 (2012) Article DOI: 10.1021/ml300106p BindingDB Entry DOI: 10.7270/Q2DZ09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Biotin--protein ligase (Homo sapiens (Human)) | BDBM50039492![]() (CHEMBL1231498) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska-Lincoln Curated by ChEMBL | Assay Description Inhibition of human recombinant HLCS using P67 as substrate after 2 hrs relative to vehicle-treated control | Bioorg Med Chem Lett 24: 5568-71 (2014) Article DOI: 10.1016/j.bmcl.2014.11.010 BindingDB Entry DOI: 10.7270/Q2W097KM | |||||||||||
More data for this Ligand-Target Pair |