Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R] (Rattus norvegicus (Rat)) | BDBM223201 (β-Sulfopyruvate) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | DrugBank KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R] (Rattus norvegicus (Rat)) | BDBM50366413 (PHOSPHOENOLPYRUVATE) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.89E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R] (Rattus norvegicus (Rat)) | BDBM23230 (2-Oxosuccinic acid | 2-oxobutanedioic acid | Oxalo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | 4.41E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] [H477R] (Rattus norvegicus (Rat)) | BDBM223202 (β,γ-methyleneguanosine 5′-triphosp...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.96E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Waterloo | Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE... | Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV | |||||||||||
More data for this Ligand-Target Pair |