BindingDB PrimarySearch

Found 40 hits of kd for UniProtKB: P63073
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316302 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543775 (CHEMBL4640985) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543775 (CHEMBL4640985) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316303 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316303 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316303 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543779 (CHEMBL4635767) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543779 (CHEMBL4635767) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543773 (CHEMBL4636472) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543774 (CHEMBL4640855) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316305 (((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543778 (CHEMBL4640425) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316305 (((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316304 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Binding affinity to murine eIF4E assessed as intrinsic fluorescence quenching of tryptophan residues by fluorescence spectrophotometric method				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316305 (((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316306 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316307 (((2R,3S,4R,5R)-5-(2-Amino-7-(4-chlorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316304 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Inhibition of fluorescein-labeled m7GDPC4H5 binding to mouse eIF4E (28 to 217 residues) by MST method				Bioorg Med Chem 26: 191-199 (2018) Article DOI: 10.1016/j.bmc.2017.11.032 BindingDB Entry DOI: 10.7270/Q2DZ0BWS
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316308 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-chlorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316306 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316309 (((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316310 (((2R,3S,4R,5R)-5-(2-Amino-7-(2-chloro-5-fluorobenz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316311 (((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316311 (((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.39E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316312 (((2R,3S,4R,5R)-5-(2-Amino-7-(4-carboxybenzyl)-6-ox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.59E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50452630 (CHEMBL4203412) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Inhibition of fluorescein-labeled m7GDPC4H5 binding to mouse eIF4E (28 to 217 residues) by MST method				Bioorg Med Chem 26: 191-199 (2018) Article DOI: 10.1016/j.bmc.2017.11.032 BindingDB Entry DOI: 10.7270/Q2DZ0BWS
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316313 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-methoxybenzyl)-6-ox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316304 (((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316315 (((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	7.51E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316314 (((2R,3S,4R,5R)-5-(2-Amino-6-oxo-7-(3-(trifluoromet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.56E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316315 (((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	8.22E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316316 (((2R,3S,4R,5R)-5-(2-Amino-7-(naphthalen-2-ylmethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.05E+3	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543776 (CHEMBL4647306) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543777 (CHEMBL4632744) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543777 (CHEMBL4632744) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50543780 (CHEMBL4646578) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Displacement of pyrene-labeled 7-methylguanosine-pentaphosphate probe from murine eIF4E assessed as decrease in fluorescence intensity incubated for ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115523 BindingDB Entry DOI: 10.7270/Q2BZ69MF
University of Warsaw Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316317 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-nitrobenzyl)-6-oxo-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316318 (((2R,3S,4R,5R)-5-(2-Amino-7-(3-methylbenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316319 (((2R,3S,4R,5R)-5-(2-Amino-7-(2,5-dichlorobenzyl)-6...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Mus musculus)	BDBM50316320 (((2R,3S,4R,5R)-5-(2-Amino-7-(2-methylbenzyl)-6-oxo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.91E+4	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFA				Eur J Med Chem 45: 1304-13 (2010) Article DOI: 10.1016/j.ejmech.2009.11.054 BindingDB Entry DOI: 10.7270/Q21C1X1Q
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)