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Compile Data Set for Download or QSAR

Found 1540 hits Enz. Inhib. hit(s) with all data for entry = 2046   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351405
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2-bromo-4- (trifluorome...)
Show SMILES COc1cc2c(Nc3ccc(cc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(4-12(14)23)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-A receptor 2


(Homo sapiens (Human))		BDBM351405
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2-bromo-4- (trifluorome...)
Show SMILES COc1cc2c(Nc3ccc(cc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(4-12(14)23)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM351405
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2-bromo-4- (trifluorome...)
Show SMILES COc1cc2c(Nc3ccc(cc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(4-12(14)23)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351405
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2-bromo-4- (trifluorome...)
Show SMILES COc1cc2c(Nc3ccc(cc3Br)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(4-12(14)23)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351406
PNG
(1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4- {[4-flu...)
Show SMILES COc1cc2c(Nc3ccc(F)cc3C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18F5N3O4/c1-31-16-5-11-15(6-17(16)34-18-8-33-19-13(24)7-32-20(18)19)28-9-29-21(11)30-14-3-2-10(23)4-12(14)22(25,26)27/h2-6,9,13,18-20H,7-8H2,1H3,(H,28,29,30)/t13-,18-,19+,20+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351407
PNG
(1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluorome...)
Show SMILES COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-A receptor 2


(Homo sapiens (Human))		BDBM351407
PNG
(1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluorome...)
Show SMILES COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM351407
PNG
(1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluorome...)
Show SMILES COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351407
PNG
(1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluorome...)
Show SMILES COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2


(Homo sapiens (Human))		BDBM351407
PNG
(1,4:3,6-dianhydro-5-O-[4-{[3-bromo-5- (trifluorome...)
Show SMILES COc1cc2c(Nc3cc(Br)cc(c3)C(F)(F)F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H18BrF4N3O4/c1-31-16-5-13-15(6-17(16)34-18-8-33-19-14(24)7-32-20(18)19)28-9-29-21(13)30-12-3-10(22(25,26)27)2-11(23)4-12/h2-6,9,14,18-20H,7-8H2,1H3,(H,28,29,30)/t14-,18-,19+,20+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351408
PNG
(1,4:3,6-dianhydro-5-O-[4-[(2- bromophenyl)amino]-6...)
Show SMILES COc1cc2c(Nc3ccccc3Br)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H19BrFN3O4/c1-27-16-6-11-15(24-10-25-21(11)26-14-5-3-2-4-12(14)22)7-17(16)30-18-9-29-19-13(23)8-28-20(18)19/h2-7,10,13,18-20H,8-9H2,1H3,(H,24,25,26)/t13-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351409
PNG
(1,4:3,6-dianhydro-5-O-[4-[(3- bromophenyl)amino]-6...)
Show SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H19BrFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-3-11(22)5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351409
PNG
(1,4:3,6-dianhydro-5-O-[4-[(3- bromophenyl)amino]-6...)
Show SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H19BrFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-3-11(22)5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351335
PNG
(7-({[(3aR,5r,6aS)-2- acetyloctahydrocyclopenta[c]p...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)C(C)=O |r|
Show InChI InChI=1S/C25H25BrClFN4O3/c1-13(33)32-9-15-5-14(6-16(15)10-32)11-35-22-8-20-17(7-21(22)34-2)25(30-12-29-20)31-19-4-3-18(26)23(27)24(19)28/h3-4,7-8,12,14-16H,5-6,9-11H2,1-2H3,(H,29,30,31)/t14-,15-,16+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351335
PNG
(7-({[(3aR,5r,6aS)-2- acetyloctahydrocyclopenta[c]p...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)C(C)=O |r|
Show InChI InChI=1S/C25H25BrClFN4O3/c1-13(33)32-9-15-5-14(6-16(15)10-32)11-35-22-8-20-17(7-21(22)34-2)25(30-12-29-20)31-19-4-3-18(26)23(27)24(19)28/h3-4,7-8,12,14-16H,5-6,9-11H2,1-2H3,(H,29,30,31)/t14-,15-,16+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351336
PNG
(N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CNC[C@@H]2C1 |r|
Show InChI InChI=1S/C23H23BrClFN4O2/c1-31-19-6-15-18(7-20(19)32-10-12-4-13-8-27-9-14(13)5-12)28-11-29-23(15)30-17-3-2-16(24)21(25)22(17)26/h2-3,6-7,11-14,27H,4-5,8-10H2,1H3,(H,28,29,30)/t12-,13-,14+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351336
PNG
(N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@@H]2CNC[C@@H]2C1 |r|
Show InChI InChI=1S/C23H23BrClFN4O2/c1-31-19-6-15-18(7-20(19)32-10-12-4-13-8-27-9-14(13)5-12)28-11-29-23(15)30-17-3-2-16(24)21(25)22(17)26/h2-3,6-7,11-14,27H,4-5,8-10H2,1H3,(H,28,29,30)/t12-,13-,14+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351337
PNG
(US9796704, Entry 5 | ethyl (3aR,6aS)-5-({[4-[(4-br...)
Show SMILES CCOC(=O)N1C[C@@H]2CC(COc3cc4ncnc(Nc5ccc(Br)c(Cl)c5F)c4cc3OC)C[C@@H]2C1 |r|
Show InChI InChI=1S/C26H27BrClFN4O4/c1-3-36-26(34)33-10-15-6-14(7-16(15)11-33)12-37-22-9-20-17(8-21(22)35-2)25(31-13-30-20)32-19-5-4-18(27)23(28)24(19)29/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,30,31,32)/t14?,15-,16+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351338
PNG
(N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)S(C)(=O)=O |r|
Show InChI InChI=1S/C24H25BrClFN4O4S/c1-34-20-7-16-19(28-12-29-24(16)30-18-4-3-17(25)22(26)23(18)27)8-21(20)35-11-13-5-14-9-31(36(2,32)33)10-15(14)6-13/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14-,15+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351338
PNG
(N-(4-bromo-3-chloro-2-fluorophenyl)-6- (methyloxy)...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C[C@H]2C1)S(C)(=O)=O |r|
Show InChI InChI=1S/C24H25BrClFN4O4S/c1-34-20-7-16-19(28-12-29-24(16)30-18-4-3-17(25)22(26)23(18)27)8-21(20)35-11-13-5-14-9-31(36(2,32)33)10-15(14)6-13/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14-,15+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351339
PNG
(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5r,6aS)...)
Show SMILES CCN1C[C@@H]2C[C@H](COc3cc4ncnc(Nc5ccc(Cl)c(Cl)c5F)c4cc3OC)C[C@@H]2C1 |r|
Show InChI InChI=1S/C25H27Cl2FN4O2/c1-3-32-10-15-6-14(7-16(15)11-32)12-34-22-9-20-17(8-21(22)33-2)25(30-13-29-20)31-19-5-4-18(26)23(27)24(19)28/h4-5,8-9,13-16H,3,6-7,10-12H2,1-2H3,(H,29,30,31)/t14-,15-,16+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351282
PNG
(N-(3,4-dichloro-2-fluorophenyl)-6- (methyloxy)-7-(...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(CC(C)C)C[C@H]2C1 |r|
Show InChI InChI=1S/C27H31Cl2FN4O2/c1-15(2)10-34-11-17-6-16(7-18(17)12-34)13-36-24-9-22-19(8-23(24)35-3)27(32-14-31-22)33-21-5-4-20(28)25(29)26(21)30/h4-5,8-9,14-18H,6-7,10-13H2,1-3H3,(H,31,32,33)/t16-,17-,18+
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351283
PNG
(N-(3,4-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351284
PNG
(N-(4-bromo-3-chloro-2-fluorophenyl)-7- ({[(3aR,5s,...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25BrClFN4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351285
PNG
(N-(3-chloro-2,4-difluorophenyl)-7- ({[(3aR,5s,6aS)...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25ClF2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(26)22(25)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351286
PNG
(N-(4,5-dichloro-2-fluorophenyl)-7- ({[(3aR,5s,6aS)...)
Show SMILES COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25Cl2FN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351287
PNG
(N-(4-bromo-5-chloro-2-fluorophenyl)-7- ({[(3aR,5s,...)
Show SMILES COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25BrClFN4O2/c1-31-9-14-3-13(4-15(14)10-31)11-33-23-8-20-16(5-22(23)32-2)24(29-12-28-20)30-21-7-18(26)17(25)6-19(21)27/h5-8,12-15H,3-4,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351288
PNG
(N-(4-bromo-2,3-dichlorophenyl)-7- ({[(3aR,5s,6aS)-...)
Show SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H25BrCl2N4O2/c1-31-9-14-5-13(6-15(14)10-31)11-33-21-8-19-16(7-20(21)32-2)24(29-12-28-19)30-18-4-3-17(25)22(26)23(18)27/h3-4,7-8,12-15H,5-6,9-11H2,1-2H3,(H,28,29,30)/t13-,14+,15-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351289
PNG
(N-(3,4-dichlorophenyl)-7-({[(3aR,5s,6aS)-2- methyl...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC[C@@H]1C[C@H]2CN(C)C[C@H]2C1 |r|
Show InChI InChI=1S/C24H26Cl2N4O2/c1-30-10-15-5-14(6-16(15)11-30)12-32-23-9-21-18(8-22(23)31-2)24(28-13-27-21)29-17-3-4-19(25)20(26)7-17/h3-4,7-9,13-16H,5-6,10-12H2,1-2H3,(H,27,28,29)/t14-,15+,16-
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351410
PNG
(1,4:3,6-dianhydro-5-O-[4-[(4- bromophenyl)amino]-6...)
Show SMILES COc1cc2c(Nc3ccc(Br)cc3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H19BrFN3O4/c1-27-16-6-13-15(24-10-25-21(13)26-12-4-2-11(22)3-5-12)7-17(16)30-18-9-29-19-14(23)8-28-20(18)19/h2-7,10,14,18-20H,8-9H2,1H3,(H,24,25,26)/t14-,18-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351411
PNG
(1,4:3,6-dianhydro-5-O-[4-[(3-bromo-4- methylphenyl...)
Show SMILES COc1cc2c(Nc3ccc(C)c(Br)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H21BrFN3O4/c1-11-3-4-12(5-14(11)23)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-15(24)8-29-21(19)20/h3-7,10,15,19-21H,8-9H2,1-2H3,(H,25,26,27)/t15-,19-,20+,21+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351412
PNG
(1,4:3,6-dianhydro-5-O-[4-[(5-chloro-2- methylpheny...)
Show SMILES COc1cc2c(Nc3ccc(Cl)cc3C)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C22H21ClFN3O4/c1-11-5-12(23)3-4-15(11)27-22-13-6-17(28-2)18(7-16(13)25-10-26-22)31-19-9-30-20-14(24)8-29-21(19)20/h3-7,10,14,19-21H,8-9H2,1-2H3,(H,25,26,27)/t14-,19-,20+,21+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351413
PNG
(1,4:3,6-dianhydro-2-deoxy-5-O-[4-[(3,5- dimethylph...)
Show SMILES COc1cc2c(Nc3cc(C)cc(C)c3)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C23H24FN3O4/c1-12-4-13(2)6-14(5-12)27-23-15-7-18(28-3)19(8-17(15)25-11-26-23)31-20-10-30-21-16(24)9-29-22(20)21/h4-8,11,16,20-22H,9-10H2,1-3H3,(H,25,26,27)/t16-,20-,21+,22+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM351414
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2,5- bis(methyloxy)phen...)
Show SMILES COc1ccc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)c1 |r|
Show InChI InChI=1S/C23H24FN3O6/c1-28-12-4-5-17(29-2)16(6-12)27-23-13-7-18(30-3)19(8-15(13)25-11-26-23)33-20-10-32-21-14(24)9-31-22(20)21/h4-8,11,14,20-22H,9-10H2,1-3H3,(H,25,26,27)/t14-,20-,21+,22+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351414
PNG
(1,4:3,6-dianhydro-5-O-[4-{[2,5- bis(methyloxy)phen...)
Show SMILES COc1ccc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)c1 |r|
Show InChI InChI=1S/C23H24FN3O6/c1-28-12-4-5-17(29-2)16(6-12)27-23-13-7-18(30-3)19(8-15(13)25-11-26-23)33-20-10-32-21-14(24)9-31-22(20)21/h4-8,11,14,20-22H,9-10H2,1-3H3,(H,25,26,27)/t14-,20-,21+,22+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351415
PNG
(1,4:3,6-dianhydro-5-O-[4-{[5-chloro-2,4- bis(methy...)
Show SMILES COc1cc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)cc1Cl |r|
Show InChI InChI=1S/C23H23ClFN3O6/c1-29-16-7-17(30-2)15(5-12(16)24)28-23-11-4-18(31-3)19(6-14(11)26-10-27-23)34-20-9-33-21-13(25)8-32-22(20)21/h4-7,10,13,20-22H,8-9H2,1-3H3,(H,26,27,28)/t13-,20-,21+,22+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351415
PNG
(1,4:3,6-dianhydro-5-O-[4-{[5-chloro-2,4- bis(methy...)
Show SMILES COc1cc(OC)c(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)cc1Cl |r|
Show InChI InChI=1S/C23H23ClFN3O6/c1-29-16-7-17(30-2)15(5-12(16)24)28-23-11-4-18(31-3)19(6-14(11)26-10-27-23)34-20-9-33-21-13(25)8-32-22(20)21/h4-7,10,13,20-22H,8-9H2,1-3H3,(H,26,27,28)/t13-,20-,21+,22+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351416
PNG
(1,4:3,6-dianhydro-5-O-[4-{[4-chloro-2,5- bis(methy...)
Show SMILES COc1cc(Nc2ncnc3cc(O[C@@H]4CO[C@H]5[C@H](F)CO[C@@H]45)c(OC)cc23)c(OC)cc1Cl |r|
Show InChI InChI=1S/C23H23ClFN3O6/c1-29-16-7-15(17(30-2)5-12(16)24)28-23-11-4-18(31-3)19(6-14(11)26-10-27-23)34-20-9-33-21-13(25)8-32-22(20)21/h4-7,10,13,20-22H,8-9H2,1-3H3,(H,26,27,28)/t13-,20-,21+,22+/m1/s1
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n/an/a<50n/an/an/an/an/an/a



SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351417
PNG
(1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2,4- difluorop...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H17ClF3N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(24)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(23)17(22)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351417
PNG
(1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2,4- difluorop...)
Show SMILES COc1cc2c(Nc3ccc(F)c(Cl)c3F)ncnc2cc1O[C@@H]1CO[C@H]2[C@H](F)CO[C@@H]12 |r|
Show InChI InChI=1S/C21H17ClF3N3O4/c1-29-14-4-9-13(5-15(14)32-16-7-31-19-11(24)6-30-20(16)19)26-8-27-21(9)28-12-3-2-10(23)17(22)18(12)25/h2-5,8,11,16,19-20H,6-7H2,1H3,(H,26,27,28)/t11-,16-,19+,20+/m1/s1
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351418
PNG
(N-(3,4-dichlorophenyl)-7-[({5- [(dimethylamino)met...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(CN(C)C)n1
Show InChI InChI=1S/C21H20Cl2N6O3/c1-29(2)9-20-27-19(28-32-20)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM351418
PNG
(N-(3,4-dichlorophenyl)-7-[({5- [(dimethylamino)met...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(CN(C)C)n1
Show InChI InChI=1S/C21H20Cl2N6O3/c1-29(2)9-20-27-19(28-32-20)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351418
PNG
(N-(3,4-dichlorophenyl)-7-[({5- [(dimethylamino)met...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(CN(C)C)n1
Show InChI InChI=1S/C21H20Cl2N6O3/c1-29(2)9-20-27-19(28-32-20)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351419
PNG
(N-(3,4-dichlorophenyl)-7-[({3- [(dimethylamino)met...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN(C)C)no1
Show InChI InChI=1S/C21H20Cl2N6O3/c1-29(2)9-19-27-20(32-28-19)10-31-18-8-16-13(7-17(18)30-3)21(25-11-24-16)26-12-4-5-14(22)15(23)6-12/h4-8,11H,9-10H2,1-3H3,(H,24,25,26)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Ephrin type-B receptor 4


(Homo sapiens (Human))		BDBM351420
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(4-m...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)no1
Show InChI InChI=1S/C24H25Cl2N7O3/c1-32-5-7-33(8-6-32)12-22-30-23(36-31-22)13-35-21-11-19-16(10-20(21)34-2)24(28-14-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,14H,5-8,12-13H2,1-2H3,(H,27,28,29)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM351420
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(4-m...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)no1
Show InChI InChI=1S/C24H25Cl2N7O3/c1-32-5-7-33(8-6-32)12-22-30-23(36-31-22)13-35-21-11-19-16(10-20(21)34-2)24(28-14-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,14H,5-8,12-13H2,1-2H3,(H,27,28,29)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351420
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-[({3- [(4-m...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCN(C)CC2)no1
Show InChI InChI=1S/C24H25Cl2N7O3/c1-32-5-7-33(8-6-32)12-22-30-23(36-31-22)13-35-21-11-19-16(10-20(21)34-2)24(28-14-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,14H,5-8,12-13H2,1-2H3,(H,27,28,29)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351421
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5- piper...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCNCC1
Show InChI InChI=1S/C23H22Cl2N6O3/c1-32-19-9-15-18(27-12-28-22(15)29-14-2-3-16(24)17(25)8-14)10-20(19)33-11-21-30-23(34-31-21)13-4-6-26-7-5-13/h2-3,8-10,12-13,26H,4-7,11H2,1H3,(H,27,28,29)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351422
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[5- (1-me...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(n1)C1CCN(C)CC1
Show InChI InChI=1S/C24H24Cl2N6O3/c1-32-7-5-14(6-8-32)24-30-22(31-35-24)12-34-21-11-19-16(10-20(21)33-2)23(28-13-27-19)29-15-3-4-17(25)18(26)9-15/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,27,28,29)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM351423
PNG
(N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[3- (morp...)
Show SMILES COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CN2CCOCC2)no1
Show InChI InChI=1S/C23H22Cl2N6O4/c1-32-19-9-15-18(26-13-27-23(15)28-14-2-3-16(24)17(25)8-14)10-20(19)34-12-22-29-21(30-35-22)11-31-4-6-33-7-5-31/h2-3,8-10,13H,4-7,11-12H2,1H3,(H,26,27,28)
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SYMPHONY EVOLUTION, INC.

US Patent


Assay Description
In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...

US Patent US9796704 (2017)


BindingDB Entry DOI: 10.7270/Q28K7C6V
More data for this
Ligand-Target Pair
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