Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Caspase-3 (Homo sapiens (Human)) | BDBM35221![]() (pyrimidoindolone, 25b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.29 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35223![]() (pyrimidoindolone, 25d) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.32 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35202![]() (pyrimidoindolone, 11k) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35220![]() (pyrimidoindolone, 25a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35203![]() (pyrimidoindolone, 11l) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.43 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35206![]() (pyrimidoindolone, 14a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.99 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM19730![]() (3,3-dimethyl-8-{[(2S)-2-(phenoxymethyl)pyrrolidine...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35204![]() (pyrimidoindolone, 11m) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.18 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35199![]() (pyrimidoindolone, 11h) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.81 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35205![]() (pyrimidoindolone, 11n) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.1 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35200![]() (pyrimidoindolone, 11i) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35192![]() (pyrimidoindolone, 11a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.8 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35201![]() (pyrimidoindolone, 11j) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35224![]() (pyrimidoindolone, 25e) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35193![]() (pyrimidoindolone, 11b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13.8 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35207![]() (pyrimidoindolone, 14b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14.3 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35222![]() (pyrimidoindolone, 25c) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14.8 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35197![]() (pyrimidoindolone, 11f) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35225![]() (pyrimidoindolone, 25f) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 24.6 | n/a | n/a | n/a | n/a | n/a | 25 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35195![]() (pyrimidoindolone, 11d) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35194![]() (pyrimidoindolone, 11c) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35208![]() (pyrimidoindolone, 14c) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43.6 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35209![]() (pyrimidoindolone, 14d) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35196![]() (pyrimidoindolone, 11e) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35198![]() (pyrimidoindolone, 11g) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35213![]() (pyrimidoindolone, 22b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 148 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35214![]() (pyrimidoindolone, 22c) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 191 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35215![]() (pyrimidoindolone, 22d) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35212![]() (pyrimidoindolone, 22a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 364 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35216![]() (pyrimidoindolone, 22e) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35217![]() (pyrimidoindolone, 22f) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35219![]() (pyrimidoindolone, 22h) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.39E+3 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35218![]() (pyrimidoindolone, 22g) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.52E+3 | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35211![]() (pyrimidoindolone, 19b) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Caspase-3 (Homo sapiens (Human)) | BDBM35210![]() (pyrimidoindolone, 19a) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.2 | 23 |
Wyeth Research | Assay Description Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ... | Bioorg Med Chem 17: 7755-68 (2009) Article DOI: 10.1016/j.bmc.2009.09.036 BindingDB Entry DOI: 10.7270/Q2BG2M9S | |||||||||||
More data for this Ligand-Target Pair |