Compile Data Set for Download or QSAR

Found 296 hits Enz. Inhib. hit(s) with all data for entry = 474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270883 (7-(benzenesulfonyl)-4-(cyclohex-1-en-1-yl)-5H-pyrr...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C18H18N4O2S/c19-18-17(25(23,24)13-9-5-2-6-10-13)16-15(22-18)14(20-11-21-16)12-7-3-1-4-8-12/h2,5-7,9-11,22H,1,3-4,8,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270884 (3-(benzenesulfonyl)-N-(4,4-difluorocyclohexyl)-1H-...) Show SMILES FC1(F)CCC(CC1)Nc1[nH]c2ncccc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H19F2N3O2S/c20-19(21)10-8-13(9-11-19)23-18-16(15-7-4-12-22-17(15)24-18)27(25,26)14-5-2-1-3-6-14/h1-7,12-13,23H,8-11H2,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270885 (7-(benzenesulfonyl)-4-cyclohexyl-5H-pyrrolo[3,2-d]...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C18H20N4O2S/c19-18-17(25(23,24)13-9-5-2-6-10-13)16-15(22-18)14(20-11-21-16)12-7-3-1-4-8-12/h2,5-6,9-12,22H,1,3-4,7-8,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270886 (4-cyclohexyl-7-[(4-methoxybenzene)sulfonyl]-5H-pyr...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1CCCCC1 Show InChI InChI=1S/C19H22N4O3S/c1-26-13-7-9-14(10-8-13)27(24,25)18-17-16(23-19(18)20)15(21-11-22-17)12-5-3-2-4-6-12/h7-12,23H,2-6,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270887 (4-(cyclohex-1-en-1-yl)-7-[(4-methoxybenzene)sulfon...) Show SMILES COc1ccc(cc1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1=CCCCC1 |t:24| Show InChI InChI=1S/C19H20N4O3S/c1-26-13-7-9-14(10-8-13)27(24,25)18-17-16(23-19(18)20)15(21-11-22-17)12-5-3-2-4-6-12/h5,7-11,23H,2-4,6,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270888 (7-(benzenesulfonyl)-4-(morpholin-4-yl)-5H-pyrrolo[...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C16H17N5O3S/c17-15-14(25(22,23)11-4-2-1-3-5-11)12-13(20-15)16(19-10-18-12)21-6-8-24-9-7-21/h1-5,10,20H,6-9,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	273	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270889 (7-(2-fluorobenzenesulfonyl)-2-methyl-4-(2,2,3-trim...) Show SMILES CC1N(CCOC1(C)C)c1nc(C)nc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270890 (7-(benzenesulfonyl)-4-(piperidin-1-yl)-5H-pyrrolo[...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C17H19N5O2S/c18-16-15(25(23,24)12-7-3-1-4-8-12)13-14(21-16)17(20-11-19-13)22-9-5-2-6-10-22/h1,3-4,7-8,11,21H,2,5-6,9-10,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270891 (7-(benzenesulfonyl)-4-phenyl-5H-pyrrolo[3,2-d]pyri...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C18H14N4O2S/c19-18-17(25(23,24)13-9-5-2-6-10-13)16-15(22-18)14(20-11-21-16)12-7-3-1-4-8-12/h1-11,22H,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270892 (7-(benzenesulfonyl)-4-[(E)-2-cyclopropylethenyl]-5...) Show SMILES Nc1[nH]c2c(\C=C\C3CC3)ncnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H16N4O2S/c18-17-16(24(22,23)12-4-2-1-3-5-12)15-14(21-17)13(19-10-20-15)9-8-11-6-7-11/h1-5,8-11,21H,6-7,18H2/b9-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	626	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270893 (3-(benzenesulfonyl)-6-chloro-1H-pyrrolo[3,2-b]pyri...) Show SMILES Nc1[nH]c2cc(Cl)cnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C13H10ClN3O2S/c14-8-6-10-11(16-7-8)12(13(15)17-10)20(18,19)9-4-2-1-3-5-9/h1-7,17H,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270894 (7-(benzenesulfonyl)-4-(prop-1-en-2-yl)-5H-pyrrolo[...) Show SMILES CC(=C)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H14N4O2S/c1-9(2)11-12-13(18-8-17-11)14(15(16)19-12)22(20,21)10-6-4-3-5-7-10/h3-8,19H,1,16H2,2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	355	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270895 (6-amino-4-(cyclohex-1-en-1-yl)-N-(4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)N(C)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1=CCCCC1 |t:26| Show InChI InChI=1S/C20H23N5O3S/c1-25(14-8-10-15(28-2)11-9-14)29(26,27)19-18-17(24-20(19)21)16(22-12-23-18)13-6-4-3-5-7-13/h6,8-12,24H,3-5,7,21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	267	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270896 (7-(benzenesulfonyl)-4-(2-cyclopropylethyl)-5H-pyrr...) Show SMILES Nc1[nH]c2c(CCC3CC3)ncnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N4O2S/c18-17-16(24(22,23)12-4-2-1-3-5-12)15-14(21-17)13(19-10-20-15)9-8-11-6-7-11/h1-5,10-11,21H,6-9,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.58E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270897 (7-(benzenesulfonyl)-4-(propan-2-yl)-5H-pyrrolo[3,2...) Show SMILES CC(C)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H16N4O2S/c1-9(2)11-12-13(18-8-17-11)14(15(16)19-12)22(20,21)10-6-4-3-5-7-10/h3-9,19H,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270898 (7-(benzenesulfonyl)-4-(3-methoxypyrrolidin-1-yl)-5...) Show SMILES COC1CCN(C1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270899 (3-(benzenesulfonyl)-7-(cyclohex-1-en-1-yl)-1H-pyrr...) Show SMILES Nc1[nH]c2c(cncc2c1S(=O)(=O)c1ccccc1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C19H19N3O2S/c20-19-18(25(23,24)14-9-5-2-6-10-14)16-12-21-11-15(17(16)22-19)13-7-3-1-4-8-13/h2,5-7,9-12,22H,1,3-4,8,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270900 (3-(benzenesulfonyl)-7-(cyclohex-1-en-1-yl)-1H-pyrr...) Show SMILES Nc1[nH]c2c(nccc2c1S(=O)(=O)c1ccccc1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C19H19N3O2S/c20-19-18(25(23,24)14-9-5-2-6-10-14)15-11-12-21-16(17(15)22-19)13-7-3-1-4-8-13/h2,5-7,9-12,22H,1,3-4,8,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	528	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270901 (4-(cyclohex-1-en-1-yl)-7-(pyridine-2-sulfonyl)-5H-...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccn1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C17H17N5O2S/c18-17-16(25(23,24)12-8-4-5-9-19-12)15-14(22-17)13(20-10-21-15)11-6-2-1-3-7-11/h4-6,8-10,22H,1-3,7,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270902 (7-(benzenesulfonyl)-4-(cyclohex-1-en-1-yl)-2-methy...) Show SMILES Cc1nc(C2=CCCCC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1 |t:4| Show InChI InChI=1S/C19H20N4O2S/c1-12-21-15(13-8-4-2-5-9-13)16-17(22-12)18(19(20)23-16)26(24,25)14-10-6-3-7-11-14/h3,6-8,10-11,23H,2,4-5,9,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270903 (7-[(4-chlorobenzene)sulfonyl]-4-(cyclohex-1-en-1-y...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(Cl)cc1)C1=CCCCC1 |t:23| Show InChI InChI=1S/C18H17ClN4O2S/c19-12-6-8-13(9-7-12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-4-2-1-3-5-11/h4,6-10,23H,1-3,5,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270904 (7-(benzenesulfonyl)-4-cyclopentyl-5H-pyrrolo[3,2-d...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)C1CCCC1 Show InChI InChI=1S/C17H18N4O2S/c18-17-16(24(22,23)12-8-2-1-3-9-12)15-14(21-17)13(19-10-20-15)11-6-4-5-7-11/h1-3,8-11,21H,4-7,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270905 (7-(benzenesulfonyl)-4-(cyclopent-1-en-1-yl)-5H-pyr...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)C1=CCCC1 |t:22| Show InChI InChI=1S/C17H16N4O2S/c18-17-16(24(22,23)12-8-2-1-3-9-12)15-14(21-17)13(19-10-20-15)11-6-4-5-7-11/h1-3,6,8-10,21H,4-5,7,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270906 (7-(benzenesulfonyl)-4-(4,4-difluoropiperidin-1-yl)...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC(F)(F)CC1 Show InChI InChI=1S/C17H17F2N5O2S/c18-17(19)6-8-24(9-7-17)16-13-12(21-10-22-16)14(15(20)23-13)27(25,26)11-4-2-1-3-5-11/h1-5,10,23H,6-9,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270907 (4-(cyclohex-1-en-1-yl)-7-[(4-fluorobenzene)sulfony...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(F)cc1)C1=CCCCC1 |t:23| Show InChI InChI=1S/C18H17FN4O2S/c19-12-6-8-13(9-7-12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-4-2-1-3-5-11/h4,6-10,23H,1-3,5,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270908 (3-(benzenesulfonyl)-6-(cyclohex-1-en-1-yl)-1H-pyrr...) Show SMILES Nc1[nH]c2cc(cnc2c1S(=O)(=O)c1ccccc1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C19H19N3O2S/c20-19-18(25(23,24)15-9-5-2-6-10-15)17-16(22-19)11-14(12-21-17)13-7-3-1-4-8-13/h2,5-7,9-12,22H,1,3-4,8,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270909 (4-cyclohexyl-7-[(4-fluorobenzene)sulfonyl]-5H-pyrr...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(F)cc1)C1CCCCC1 Show InChI InChI=1S/C18H19FN4O2S/c19-12-6-8-13(9-7-12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-4-2-1-3-5-11/h6-11,23H,1-5,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270910 (7-(benzenesulfonyl)-4-(3,3-difluoropyrrolidin-1-yl...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC(F)(F)C1 Show InChI InChI=1S/C16H15F2N5O2S/c17-16(18)6-7-23(8-16)15-12-11(20-9-21-15)13(14(19)22-12)26(24,25)10-4-2-1-3-5-10/h1-5,9,22H,6-8,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	647	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270911 (7-(benzenesulfonyl)-4-(4-methoxypiperidin-1-yl)-5H...) Show SMILES COC1CCN(CC1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H21N5O3S/c1-26-12-7-9-23(10-8-12)18-15-14(20-11-21-18)16(17(19)22-15)27(24,25)13-5-3-2-4-6-13/h2-6,11-12,22H,7-10,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	399	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270912 (4-(azetidin-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC1 Show InChI InChI=1S/C15H15N5O2S/c16-14-13(23(21,22)10-5-2-1-3-6-10)11-12(19-14)15(18-9-17-11)20-7-4-8-20/h1-3,5-6,9,19H,4,7-8,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.53E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270913 (3-(benzenesulfonyl)-7-cyclohexyl-1H-pyrrolo[3,2-c]...) Show SMILES Nc1[nH]c2c(cncc2c1S(=O)(=O)c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C19H21N3O2S/c20-19-18(25(23,24)14-9-5-2-6-10-14)16-12-21-11-15(17(16)22-19)13-7-3-1-4-8-13/h2,5-6,9-13,22H,1,3-4,7-8,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270914 (7-(benzenesulfonyl)-4-(pyrrolidin-1-yl)-5H-pyrrolo...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCC1 Show InChI InChI=1S/C16H17N5O2S/c17-15-14(24(22,23)11-6-2-1-3-7-11)12-13(20-15)16(19-10-18-12)21-8-4-5-9-21/h1-3,6-7,10,20H,4-5,8-9,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270915 (4-(cyclohex-1-en-1-yl)-7-{[4-(difluoromethoxy)benz...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(OC(F)F)cc1)C1=CCCCC1 |t:26| Show InChI InChI=1S/C19H18F2N4O3S/c20-19(21)28-12-6-8-13(9-7-12)29(26,27)17-16-15(25-18(17)22)14(23-10-24-16)11-4-2-1-3-5-11/h4,6-10,19,25H,1-3,5,22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270916 (7-(benzenesulfonyl)-4-cyclohexyl-N-methyl-5H-pyrro...) Show SMILES CNc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C19H22N4O2S/c1-20-19-18(26(24,25)14-10-6-3-7-11-14)17-16(23-19)15(21-12-22-17)13-8-4-2-5-9-13/h3,6-7,10-13,20,23H,2,4-5,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270917 (7-(benzenesulfonyl)-4-(3,3-difluoropiperidin-1-yl)...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCC(F)(F)C1 Show InChI InChI=1S/C17H17F2N5O2S/c18-17(19)7-4-8-24(9-17)16-13-12(21-10-22-16)14(15(20)23-13)27(25,26)11-5-2-1-3-6-11/h1-3,5-6,10,23H,4,7-9,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.52E+3	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270918 (4-cyclohexyl-7-{[4-(difluoromethoxy)benzene]sulfon...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(OC(F)F)cc1)C1CCCCC1 Show InChI InChI=1S/C19H20F2N4O3S/c20-19(21)28-12-6-8-13(9-7-12)29(26,27)17-16-15(25-18(17)22)14(23-10-24-16)11-4-2-1-3-5-11/h6-11,19,25H,1-5,22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270919 (4-(cyclohex-1-en-t-yl)-7-[(2-fluorobenzene)sulfony...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1F)C1=CCCCC1 |t:23| Show InChI InChI=1S/C18H17FN4O2S/c19-12-8-4-5-9-13(12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-6-2-1-3-7-11/h4-6,8-10,23H,1-3,7,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270920 (4-(cyclohex-1-en-1-yl)-7-[(3-fluorobenzene)sulfony...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1cccc(F)c1)C1=CCCCC1 |t:23| Show InChI InChI=1S/C18H17FN4O2S/c19-12-7-4-8-13(9-12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-5-2-1-3-6-11/h4-5,7-10,23H,1-3,6,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270921 (4-cyclohexyl-7-[(3-fluorobenzene)sulfonyl]-5H-pyrr...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1cccc(F)c1)C1CCCCC1 Show InChI InChI=1S/C18H19FN4O2S/c19-12-7-4-8-13(9-12)26(24,25)17-16-15(23-18(17)20)14(21-10-22-16)11-5-2-1-3-6-11/h4,7-11,23H,1-3,5-6,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270922 (7-(benzenesulfonyl)-4-(cyclohex-1-en-1-yl)-2-ethyl...) Show SMILES CCc1nc(C2=CCCCC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1 |t:5| Show InChI InChI=1S/C20H22N4O2S/c1-2-15-22-16(13-9-5-3-6-10-13)17-18(23-15)19(20(21)24-17)27(25,26)14-11-7-4-8-12-14/h4,7-9,11-12,24H,2-3,5-6,10,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270923 (7-(benzenesulfonyl)-4-cyclohexyl-2-methyl-5H-pyrro...) Show SMILES Cc1nc(C2CCCCC2)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H22N4O2S/c1-12-21-15(13-8-4-2-5-9-13)16-17(22-12)18(19(20)23-16)26(24,25)14-10-6-3-7-11-14/h3,6-7,10-11,13,23H,2,4-5,8-9,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270924 (4-(cyclohex-1-en-1-yl)-7-[(4-methylbenzene)sulfony...) Show SMILES Cc1ccc(cc1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1=CCCCC1 |t:23| Show InChI InChI=1S/C19H20N4O2S/c1-12-7-9-14(10-8-12)26(24,25)18-17-16(23-19(18)20)15(21-11-22-17)13-5-3-2-4-6-13/h5,7-11,23H,2-4,6,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270925 (4-cyclohexyl-7-(6-methoxypyridine-3-sulfonyl)-5H-p...) Show SMILES COc1ccc(cn1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1CCCCC1 Show InChI InChI=1S/C18H21N5O3S/c1-26-13-8-7-12(9-20-13)27(24,25)17-16-15(23-18(17)19)14(21-10-22-16)11-5-3-2-4-6-11/h7-11,23H,2-6,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270926 (4-(cyclohex-1-en-1-yl)-7-(6-methoxypyridine-3-sulf...) Show SMILES COc1ccc(cn1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1=CCCCC1 |t:24| Show InChI InChI=1S/C18H19N5O3S/c1-26-13-8-7-12(9-20-13)27(24,25)17-16-15(23-18(17)19)14(21-10-22-16)11-5-3-2-4-6-11/h5,7-10,23H,2-4,6,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	173	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270927 (4-cyclohexyl-7-[(4-methylbenzene)sulfonyl]-5H-pyrr...) Show SMILES Cc1ccc(cc1)S(=O)(=O)c1c(N)[nH]c2c(ncnc12)C1CCCCC1 Show InChI InChI=1S/C19H22N4O2S/c1-12-7-9-14(10-8-12)26(24,25)18-17-16(23-19(18)20)15(21-11-22-17)13-5-3-2-4-6-13/h7-11,13,23H,2-6,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270928 (7-(benzenesulfonyl)-4-(3,3-dimethylpyrrolidin-4-yl...) Show SMILES CC1(C)CCN(C1)c1ncnc2c(c(N)[nH]c12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H21N5O2S/c1-18(2)8-9-23(10-18)17-14-13(20-11-21-17)15(16(19)22-14)26(24,25)12-6-4-3-5-7-12/h3-7,11,22H,8-10,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	153	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270929 (7-(benzenesulfonyl)-4-(4-fluoropiperidin-1-yl)-5H-...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCC(F)CC1 Show InChI InChI=1S/C17H18FN5O2S/c18-11-6-8-23(9-7-11)17-14-13(20-10-21-17)15(16(19)22-14)26(24,25)12-4-2-1-3-5-12/h1-5,10-11,22H,6-9,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	358	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270930 (4-(azepan-1-yl)-7-(benzenesulfonyl)-5H-pyrrolo[3,2...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccccc1)N1CCCCCC1 Show InChI InChI=1S/C18H21N5O2S/c19-17-16(26(24,25)13-8-4-3-5-9-13)14-15(22-17)18(21-12-20-14)23-10-6-1-2-7-11-23/h3-5,8-9,12,22H,1-2,6-7,10-11,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	209	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270931 (4-(cyclohex-1-en-1-yl)-7-(cyclohexanesulfonyl)-5H-...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)C1CCCCC1)C1=CCCCC1 |t:22| Show InChI InChI=1S/C18H24N4O2S/c19-18-17(25(23,24)13-9-5-2-6-10-13)16-15(22-18)14(20-11-21-16)12-7-3-1-4-8-12/h7,11,13,22H,1-6,8-10,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	113	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM270932 (4-(cyclohex-1-en-1-yl)-7-[(3,4-difluorobenzene)sul...) Show SMILES Nc1[nH]c2c(ncnc2c1S(=O)(=O)c1ccc(F)c(F)c1)C1=CCCCC1 |t:24| Show InChI InChI=1S/C18H16F2N4O2S/c19-12-7-6-11(8-13(12)20)27(25,26)17-16-15(24-18(17)21)14(22-9-23-16)10-4-2-1-3-5-10/h4,6-9,24H,1-3,5,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...				US Patent US10059713 (2018) BindingDB Entry DOI: 10.7270/Q2251M7X
					More data for this Ligand-Target Pair

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