Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50001378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277622 (CHEMBL4162390) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(nc2C)N(C)C)c(OC)c1 Show InChI InChI=1S/C18H21N5O2S/c1-11-16(26-18(20-11)23(2)3)14-8-9-19-17(22-14)21-13-7-6-12(24-4)10-15(13)25-5/h6-10H,1-5H3,(H,19,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277601 (CHEMBL4167646) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C20H25N5O2S2/c1-13-18(29-20(22-13)28-11-10-25(2)3)16-8-9-21-19(24-16)23-15-7-6-14(26-4)12-17(15)27-5/h6-9,12H,10-11H2,1-5H3,(H,21,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277603 (CHEMBL4167329) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCCN(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C21H27N5O2S2/c1-14-19(30-21(23-14)29-12-6-11-26(2)3)17-9-10-22-20(25-17)24-16-8-7-15(27-4)13-18(16)28-5/h7-10,13H,6,11-12H2,1-5H3,(H,22,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277602 (CHEMBL4164283) Show SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C17H19N5O2S/c1-10-15(25-17(18-2)20-10)13-7-8-19-16(22-13)21-12-6-5-11(23-3)9-14(12)24-4/h5-9H,1-4H3,(H,18,20)(H,19,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277648 (CHEMBL4159419) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCc3cccnc3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H21N5O2S2/c1-14-20(31-22(25-14)30-13-15-5-4-9-23-12-15)18-8-10-24-21(27-18)26-17-7-6-16(28-2)11-19(17)29-3/h4-12H,13H2,1-3H3,(H,24,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Binding affinity determined against ETA receptor in porcine aortic smooth muscle membrane				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277618 (CHEMBL4165526) Show SMILES Oc1ccccc1Nc1nccc(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H14N4O/c23-17-8-4-3-7-16(17)22-18-19-10-9-15(21-18)13-11-20-14-6-2-1-5-12(13)14/h1-11,20,23H,(H,19,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277604 (CHEMBL4159742) Show SMILES COCCSc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C19H22N4O3S2/c1-12-17(28-19(21-12)27-10-9-24-2)15-7-8-20-18(23-15)22-14-6-5-13(25-3)11-16(14)26-4/h5-8,11H,9-10H2,1-4H3,(H,20,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277621 (CHEMBL4174540) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN3CCOCC3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H27N5O3S2/c1-15-20(32-22(24-15)31-13-10-27-8-11-30-12-9-27)18-6-7-23-21(26-18)25-17-5-4-16(28-2)14-19(17)29-3/h4-7,14H,8-13H2,1-3H3,(H,23,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Tested for affinity towards H1 receptor in guinea pig ileum				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277620 (CHEMBL4163881) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN3CCNCC3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H28N6O2S2/c1-15-20(32-22(25-15)31-13-12-28-10-8-23-9-11-28)18-6-7-24-21(27-18)26-17-5-4-16(29-2)14-19(17)30-3/h4-7,14,23H,8-13H2,1-3H3,(H,24,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277602 (CHEMBL4164283) Show SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C17H19N5O2S/c1-10-15(25-17(18-2)20-10)13-7-8-19-16(22-13)21-12-6-5-11(23-3)9-14(12)24-4/h5-9H,1-4H3,(H,18,20)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277608 (CHEMBL4173067) Show SMILES COc1ccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C20H18N4O2/c1-25-13-7-8-18(19(11-13)26-2)24-20-21-10-9-17(23-20)15-12-22-16-6-4-3-5-14(15)16/h3-12,22H,1-2H3,(H,21,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277618 (CHEMBL4165526) Show SMILES Oc1ccccc1Nc1nccc(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H14N4O/c23-17-8-4-3-7-16(17)22-18-19-10-9-15(21-18)13-11-20-14-6-2-1-5-12(13)14/h1-11,20,23H,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277642 (CHEMBL4159438) Show SMILES COCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C23H24N4O3/c1-28-13-12-27-15-18(17-6-4-5-7-21(17)27)19-10-11-24-23(25-19)26-20-9-8-16(29-2)14-22(20)30-3/h4-11,14-15H,12-13H2,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277622 (CHEMBL4162390) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(nc2C)N(C)C)c(OC)c1 Show InChI InChI=1S/C18H21N5O2S/c1-11-16(26-18(20-11)23(2)3)14-8-9-19-17(22-14)21-13-7-6-12(24-4)10-15(13)25-5/h6-10H,1-5H3,(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Binding affinity determined against ETA receptor in porcine aortic smooth muscle membrane				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277606 (CHEMBL4159011) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(C(C)C)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C23H24N4O2/c1-15(2)27-14-18(17-7-5-6-8-21(17)27)19-11-12-24-23(25-19)26-20-10-9-16(28-3)13-22(20)29-4/h5-15H,1-4H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277601 (CHEMBL4167646) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C20H25N5O2S2/c1-13-18(29-20(22-13)28-11-10-25(2)3)16-8-9-21-19(24-16)23-15-7-6-14(26-4)12-17(15)27-5/h6-9,12H,10-11H2,1-5H3,(H,21,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277616 (CHEMBL4167344) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(CCN3CCOCC3)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C26H29N5O3/c1-32-19-7-8-23(25(17-19)33-2)29-26-27-10-9-22(28-26)21-18-31(24-6-4-3-5-20(21)24)12-11-30-13-15-34-16-14-30/h3-10,17-18H,11-16H2,1-2H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277608 (CHEMBL4173067) Show SMILES COc1ccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C20H18N4O2/c1-25-13-7-8-18(19(11-13)26-2)24-20-21-10-9-17(23-20)15-12-22-16-6-4-3-5-14(15)16/h3-12,22H,1-2H3,(H,21,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277641 (CHEMBL4169662) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(C3CCCC3)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C25H26N4O2/c1-30-18-11-12-22(24(15-18)31-2)28-25-26-14-13-21(27-25)20-16-29(17-7-3-4-8-17)23-10-6-5-9-19(20)23/h5-6,9-17H,3-4,7-8H2,1-2H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277648 (CHEMBL4159419) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCc3cccnc3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H21N5O2S2/c1-14-20(31-22(25-14)30-13-15-5-4-9-23-12-15)18-8-10-24-21(27-18)26-17-7-6-16(28-2)11-19(17)29-3/h4-12H,13H2,1-3H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277624 (CHEMBL4166250) Show SMILES CCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C23H24N4O2/c1-4-13-27-15-18(17-7-5-6-8-21(17)27)19-11-12-24-23(25-19)26-20-10-9-16(28-2)14-22(20)29-3/h5-12,14-15H,4,13H2,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277600 (CHEMBL4174162) Show SMILES CCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C22H22N4O2/c1-4-26-14-17(16-7-5-6-8-20(16)26)18-11-12-23-22(24-18)25-19-10-9-15(27-2)13-21(19)28-3/h5-14H,4H2,1-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277607 (CHEMBL4170718) Show SMILES CCCCOc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C20H24N4O3S/c1-5-6-11-27-20-22-13(2)18(28-20)16-9-10-21-19(24-16)23-15-8-7-14(25-3)12-17(15)26-4/h7-10,12H,5-6,11H2,1-4H3,(H,21,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277647 (CHEMBL4165841) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(C)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C21H20N4O2/c1-25-13-16(15-6-4-5-7-19(15)25)17-10-11-22-21(23-17)24-18-9-8-14(26-2)12-20(18)27-3/h4-13H,1-3H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Binding affinity determined against ETA receptor in porcine aortic smooth muscle membrane				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277606 (CHEMBL4159011) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(C(C)C)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C23H24N4O2/c1-15(2)27-14-18(17-7-5-6-8-21(17)27)19-11-12-24-23(25-19)26-20-10-9-16(28-3)13-22(20)29-4/h5-15H,1-4H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277622 (CHEMBL4162390) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(nc2C)N(C)C)c(OC)c1 Show InChI InChI=1S/C18H21N5O2S/c1-11-16(26-18(20-11)23(2)3)14-8-9-19-17(22-14)21-13-7-6-12(24-4)10-15(13)25-5/h6-10H,1-5H3,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277626 (CHEMBL4172170) Show SMILES COCCOc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C19H22N4O4S/c1-12-17(28-19(21-12)27-10-9-24-2)15-7-8-20-18(23-15)22-14-6-5-13(25-3)11-16(14)26-4/h5-8,11H,9-10H2,1-4H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277618 (CHEMBL4165526) Show SMILES Oc1ccccc1Nc1nccc(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H14N4O/c23-17-8-4-3-7-16(17)22-18-19-10-9-15(21-18)13-11-20-14-6-2-1-5-12(13)14/h1-11,20,23H,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277647 (CHEMBL4165841) Show SMILES COc1ccc(Nc2nccc(n2)-c2cn(C)c3ccccc23)c(OC)c1 Show InChI InChI=1S/C21H20N4O2/c1-25-13-16(15-6-4-5-7-19(15)25)17-10-11-22-21(23-17)24-18-9-8-14(26-2)12-20(18)27-3/h4-13H,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277605 (CHEMBL4162781) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(OC(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C19H22N4O3S/c1-11(2)26-19-21-12(3)17(27-19)15-8-9-20-18(23-15)22-14-7-6-13(24-4)10-16(14)25-5/h6-11H,1-5H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277603 (CHEMBL4167329) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCCN(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C21H27N5O2S2/c1-14-19(30-21(23-14)29-12-6-11-26(2)3)17-9-10-22-20(25-17)24-16-8-7-15(27-4)13-18(16)28-5/h7-10,13H,6,11-12H2,1-5H3,(H,22,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277605 (CHEMBL4162781) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(OC(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C19H22N4O3S/c1-11(2)26-19-21-12(3)17(27-19)15-8-9-20-18(23-15)22-14-7-6-13(24-4)10-16(14)25-5/h6-11H,1-5H3,(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277625 (CHEMBL4159335) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SC(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C19H22N4O2S2/c1-11(2)26-19-21-12(3)17(27-19)15-8-9-20-18(23-15)22-14-7-6-13(24-4)10-16(14)25-5/h6-11H,1-5H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277642 (CHEMBL4159438) Show SMILES COCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C23H24N4O3/c1-28-13-12-27-15-18(17-6-4-5-7-21(17)27)19-10-11-24-23(25-19)26-20-9-8-16(29-2)14-22(20)30-3/h4-11,14-15H,12-13H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Antagonistic activity towards ET- l-induced contraction in porcine coronary arteries				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277620 (CHEMBL4163881) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN3CCNCC3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H28N6O2S2/c1-15-20(32-22(25-15)31-13-12-28-10-8-23-9-11-28)18-6-7-24-21(27-18)26-17-5-4-16(29-2)14-19(17)30-3/h4-7,14,23H,8-13H2,1-3H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277602 (CHEMBL4164283) Show SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C17H19N5O2S/c1-10-15(25-17(18-2)20-10)13-7-8-19-16(22-13)21-12-6-5-11(23-3)9-14(12)24-4/h5-9H,1-4H3,(H,18,20)(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277617 (CHEMBL4168949) Show SMILES COCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC(F)F)n2)c2ccccc12 Show InChI InChI=1S/C23H22F2N4O3/c1-30-12-11-29-14-17(16-5-3-4-6-20(16)29)18-9-10-26-23(27-18)28-19-8-7-15(31-2)13-21(19)32-22(24)25/h3-10,13-14,22H,11-12H2,1-2H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277604 (CHEMBL4159742) Show SMILES COCCSc1nc(C)c(s1)-c1ccnc(Nc2ccc(OC)cc2OC)n1 Show InChI InChI=1S/C19H22N4O3S2/c1-12-17(28-19(21-12)27-10-9-24-2)15-7-8-20-18(23-15)22-14-6-5-13(25-3)11-16(14)26-4/h5-8,11H,9-10H2,1-4H3,(H,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277624 (CHEMBL4166250) Show SMILES CCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C23H24N4O2/c1-4-13-27-15-18(17-7-5-6-8-21(17)27)19-11-12-24-23(25-19)26-20-10-9-16(28-2)14-22(20)29-3/h5-12,14-15H,4,13H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277621 (CHEMBL4174540) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN3CCOCC3)nc2C)c(OC)c1 Show InChI InChI=1S/C22H27N5O3S2/c1-15-20(32-22(24-15)31-13-10-27-8-11-30-12-9-27)18-6-7-23-21(26-18)25-17-5-4-16(28-2)14-19(17)29-3/h4-7,14H,8-13H2,1-3H3,(H,23,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK2 expressed in baculovirus expression system using N-terminal TAMRA-labeled eIF4...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277608 (CHEMBL4173067) Show SMILES COc1ccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)c(OC)c1 Show InChI InChI=1S/C20H18N4O2/c1-25-13-7-8-18(19(11-13)26-2)24-20-21-10-9-17(23-20)15-12-22-16-6-4-3-5-14(15)16/h3-12,22H,1-2H3,(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277601 (CHEMBL4167646) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SCCN(C)C)nc2C)c(OC)c1 Show InChI InChI=1S/C20H25N5O2S2/c1-13-18(29-20(22-13)28-11-10-25(2)3)16-8-9-21-19(24-16)23-15-7-6-14(26-4)12-17(15)27-5/h6-9,12H,10-11H2,1-5H3,(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged MNK1 expressed in insect cells using N-terminal TAMRA-labeled eIF4E (202 to 214 res...				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50277649 (CHEMBL4161023) Show SMILES COCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC(F)(F)F)n2)c2ccccc12 Show InChI InChI=1S/C23H21F3N4O3/c1-31-12-11-30-14-17(16-5-3-4-6-20(16)30)18-9-10-27-22(28-18)29-19-8-7-15(32-2)13-21(19)33-23(24,25)26/h3-10,13-14H,11-12H2,1-2H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Binding affinity determined against ETA receptor in porcine aortic smooth muscle membrane				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50277619 (CHEMBL4166548) Show SMILES COc1ccc(Nc2nccc(n2)-c2sc(SC)nc2C)c(OC)c1 Show InChI InChI=1S/C17H18N4O2S2/c1-10-15(25-17(19-10)24-4)13-7-8-18-16(21-13)20-12-6-5-11(22-2)9-14(12)23-3/h5-9H,1-4H3,(H,18,20,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of recombinant human FLT3 using EAIYAAPFAKKK as substrate by ATP-Glo assay				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair