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Compile Data Set for Download or QSAR

Found 60 hits Enz. Inhib. hit(s) with all data for entry = 50003766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475708
PNG
(CHEMBL425592)
Show SMILES CN(C)CCC(NC(=O)Nc1ccc(cc1)C(F)(F)F)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H21ClF3N3O/c1-26(2)12-11-17(13-3-7-15(20)8-4-13)25-18(27)24-16-9-5-14(6-10-16)19(21,22)23/h3-10,17H,11-12H2,1-2H3,(H2,24,25,27)
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n/an/an/an/a 117n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475760
PNG
(CHEMBL274508)
Show SMILES CN(C)CCC(OC(=O)c1cccc(Cl)c1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H21Cl2NO2/c1-13-16(5-4-6-17(13)21)19(23)24-18(11-12-22(2)3)14-7-9-15(20)10-8-14/h4-10,18H,11-12H2,1-3H3
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n/an/an/an/a 1.12E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475709
PNG
(CHEMBL377938)
Show SMILES CN(C)CCC(NS(=O)(=O)c1ccc(C)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H23ClN2O2S/c1-14-4-10-17(11-5-14)24(22,23)20-18(12-13-21(2)3)15-6-8-16(19)9-7-15/h4-11,18,20H,12-13H2,1-3H3
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n/an/an/an/a 6.46E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475710
PNG
(CHEMBL205681)
Show SMILES CN(C)CCC(NC(=O)Nc1ccc(cc1)C(C)(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H30ClN3O/c1-22(2,3)17-8-12-19(13-9-17)24-21(27)25-20(14-15-26(4)5)16-6-10-18(23)11-7-16/h6-13,20H,14-15H2,1-5H3,(H2,24,25,27)
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n/an/an/an/a 275n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50164424
PNG
(3-(4-Chloro-phenyl)-3-(2-dimethylamino-ethyl)-isoc...)
Show SMILES CN(C)CCC1(Cc2ccccc2C(=O)O1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClNO2/c1-21(2)12-11-19(15-7-9-16(20)10-8-15)13-14-5-3-4-6-17(14)18(22)23-19/h3-10H,11-13H2,1-2H3
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n/an/an/an/a 1.12E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475711
PNG
(CHEMBL203337)
Show SMILES CN(C)CCC(NC(=O)c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H21ClN2O/c1-21(2)13-12-17(14-8-10-16(19)11-9-14)20-18(22)15-6-4-3-5-7-15/h3-11,17H,12-13H2,1-2H3,(H,20,22)
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n/an/an/an/a 1.41E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475712
PNG
(CHEMBL382477)
Show SMILES CN(C)CCC(NC(=O)NCc1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H24ClN3O/c1-23(2)13-12-18(16-8-10-17(20)11-9-16)22-19(24)21-14-15-6-4-3-5-7-15/h3-11,18H,12-14H2,1-2H3,(H2,21,22,24)
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n/an/an/an/a 2.00E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475713
PNG
(CHEMBL206661)
Show SMILES CN(C)CCC(OC(=O)c1ccc2ccccc2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H22ClNO2/c1-24(2)14-13-21(17-9-11-20(23)12-10-17)26-22(25)19-8-7-16-5-3-4-6-18(16)15-19/h3-12,15,21H,13-14H2,1-2H3
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n/an/an/an/a 2.09E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475714
PNG
(CHEMBL208536)
Show SMILES COc1cccc(NC(=O)OC(CCN(C)C)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H23ClN2O3/c1-22(2)12-11-18(14-7-9-15(20)10-8-14)25-19(23)21-16-5-4-6-17(13-16)24-3/h4-10,13,18H,11-12H2,1-3H3,(H,21,23)
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n/an/an/an/a 1.12E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475715
PNG
(CHEMBL203051)
Show SMILES CN(C)CCC(OC(=O)Nc1ccc(cc1)C(F)(F)F)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClF3N2O2/c1-25(2)12-11-17(13-3-7-15(20)8-4-13)27-18(26)24-16-9-5-14(6-10-16)19(21,22)23/h3-10,17H,11-12H2,1-2H3,(H,24,26)
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n/an/an/an/a 251n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475716
PNG
(CHEMBL205157)
Show SMILES CCc1ccccc1C(=O)N[C@@H](CCN(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H25ClN2O/c1-4-15-7-5-6-8-18(15)20(24)22-19(13-14-23(2)3)16-9-11-17(21)12-10-16/h5-12,19H,4,13-14H2,1-3H3,(H,22,24)/t19-/m0/s1
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n/an/an/an/a 1.02E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475717
PNG
(CHEMBL208436)
Show SMILES CN(C)CCC(OC(=O)c1ccc(Br)cc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H21BrClNO2/c1-13-12-15(20)6-9-17(13)19(23)24-18(10-11-22(2)3)14-4-7-16(21)8-5-14/h4-9,12,18H,10-11H2,1-3H3
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n/an/an/an/a 1.07E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475718
PNG
(CHEMBL208886)
Show SMILES COc1ccc(cc1)C(=O)OC(CCN(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H22ClNO3/c1-21(2)13-12-18(14-4-8-16(20)9-5-14)24-19(22)15-6-10-17(23-3)11-7-15/h4-11,18H,12-13H2,1-3H3
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n/an/an/an/a 2.19E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475719
PNG
(CHEMBL205735)
Show SMILES COc1ccc(NC(=O)NC(CCN(C)C)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H24ClN3O2/c1-23(2)13-12-18(14-4-6-15(20)7-5-14)22-19(24)21-16-8-10-17(25-3)11-9-16/h4-11,18H,12-13H2,1-3H3,(H2,21,22,24)
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n/an/an/an/a 2.00E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475720
PNG
(CHEMBL206719)
Show SMILES CN(C)CCC(OC(=O)c1cccc2ccccc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H22ClNO2/c1-24(2)15-14-21(17-10-12-18(23)13-11-17)26-22(25)20-9-5-7-16-6-3-4-8-19(16)20/h3-13,21H,14-15H2,1-2H3
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n/an/an/an/a 2.29E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475721
PNG
(CHEMBL206551)
Show SMILES CN(C)CCC(NC(=O)Nc1ccc2ccccc2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H24ClN3O/c1-26(2)14-13-21(17-7-10-19(23)11-8-17)25-22(27)24-20-12-9-16-5-3-4-6-18(16)15-20/h3-12,15,21H,13-14H2,1-2H3,(H2,24,25,27)
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n/an/an/an/a 288n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475722
PNG
(CHEMBL205390)
Show SMILES CN(C)CCC(NC(=O)Nc1ccccc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H24ClN3O/c1-14-6-4-5-7-17(14)21-19(24)22-18(12-13-23(2)3)15-8-10-16(20)11-9-15/h4-11,18H,12-13H2,1-3H3,(H2,21,22,24)
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n/an/an/an/a 2.29E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475723
PNG
(CHEMBL377973)
Show SMILES CN(C)CCC(OC(=O)Nc1ccc(cc1)C(C)(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H29ClN2O2/c1-22(2,3)17-8-12-19(13-9-17)24-21(26)27-20(14-15-25(4)5)16-6-10-18(23)11-7-16/h6-13,20H,14-15H2,1-5H3,(H,24,26)
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n/an/an/an/a 1.82E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475724
PNG
(CHEMBL382401)
Show SMILES CN(C)CCC(NC(=O)c1cc(C)ccc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H25ClN2O/c1-14-5-6-15(2)18(13-14)20(24)22-19(11-12-23(3)4)16-7-9-17(21)10-8-16/h5-10,13,19H,11-12H2,1-4H3,(H,22,24)
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n/an/an/an/a 2.88E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475725
PNG
(CHEMBL206811)
Show SMILES CN(C)CCC(NC(=O)Nc1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClN3O/c1-28(2)17-16-23(20-8-12-21(25)13-9-20)27-24(29)26-22-14-10-19(11-15-22)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3,(H2,26,27,29)
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n/an/an/an/a 145n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475726
PNG
(CHEMBL205859)
Show SMILES CN(C)CCC(OC(=O)c1ccc(cc1)C(F)(F)F)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H19ClF3NO2/c1-24(2)12-11-17(13-5-9-16(20)10-6-13)26-18(25)14-3-7-15(8-4-14)19(21,22)23/h3-10,17H,11-12H2,1-2H3
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n/an/an/an/a 1.74E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475727
PNG
(CHEMBL380704)
Show SMILES COc1cccc(C(=O)NC(CCN(C)C)c2ccc(Cl)cc2)c1C
Show InChI InChI=1S/C20H25ClN2O2/c1-14-17(6-5-7-19(14)25-4)20(24)22-18(12-13-23(2)3)15-8-10-16(21)11-9-15/h5-11,18H,12-13H2,1-4H3,(H,22,24)
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n/an/an/an/a 4.27E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475728
PNG
(CHEMBL205201)
Show SMILES CN(C)CCC(NC(=O)c1cccc(C)c1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H25ClN2O/c1-14-6-5-7-18(15(14)2)20(24)22-19(12-13-23(3)4)16-8-10-17(21)11-9-16/h5-11,19H,12-13H2,1-4H3,(H,22,24)
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n/an/an/an/a 3.63E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50416336
PNG
(CHEMBL380346)
Show SMILES CN(C)CCC1(Cc2cc(C)c(C)cc2C(=O)O1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H24ClNO2/c1-14-11-16-13-21(9-10-23(3)4,17-5-7-18(22)8-6-17)25-20(24)19(16)12-15(14)2/h5-8,11-12H,9-10,13H2,1-4H3
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n/an/an/an/a 135n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475729
PNG
(CHEMBL206596)
Show SMILES CN(C)CCC(NC(=O)Cc1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O/c1-22(2)13-12-18(16-8-10-17(20)11-9-16)21-19(23)14-15-6-4-3-5-7-15/h3-11,18H,12-14H2,1-2H3,(H,21,23)
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n/an/an/an/a 1.95E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475730
PNG
(CHEMBL204516)
Show SMILES CN(C)CCC(OC(=O)c1cn(C)c2ccccc12)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClN2O2/c1-23(2)13-12-20(15-8-10-16(22)11-9-15)26-21(25)18-14-24(3)19-7-5-4-6-17(18)19/h4-11,14,20H,12-13H2,1-3H3
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n/an/an/an/a 1.51E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475731
PNG
(CHEMBL380745)
Show SMILES COc1ccc(NC(=O)OC(CCN(C)C)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H23ClN2O3/c1-22(2)13-12-18(14-4-6-15(20)7-5-14)25-19(23)21-16-8-10-17(24-3)11-9-16/h4-11,18H,12-13H2,1-3H3,(H,21,23)
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n/an/an/an/a 1.66E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475732
PNG
(CHEMBL202725)
Show SMILES CN(C)CCC(NC(=O)c1ccccc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O/c1-14-6-4-5-7-17(14)19(23)21-18(12-13-22(2)3)15-8-10-16(20)11-9-15/h4-11,18H,12-13H2,1-3H3,(H,21,23)
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n/an/an/an/a 3.55E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475733
PNG
(CHEMBL205254)
Show SMILES CN(C)CCC(NC(=O)c1ccc(cc1)N(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H26ClN3O/c1-23(2)14-13-19(15-5-9-17(21)10-6-15)22-20(25)16-7-11-18(12-8-16)24(3)4/h5-12,19H,13-14H2,1-4H3,(H,22,25)
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n/an/an/an/a 1.35E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475734
PNG
(CHEMBL381756)
Show SMILES CN(C)CCC(NC(=O)c1cc(C)c(C)cc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H27ClN2O/c1-14-12-16(3)19(13-15(14)2)21(25)23-20(10-11-24(4)5)17-6-8-18(22)9-7-17/h6-9,12-13,20H,10-11H2,1-5H3,(H,23,25)
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n/an/an/an/a 1.78E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475735
PNG
(CHEMBL206371)
Show SMILES CN(C)CCC(NC(=O)c1cccc(Cl)c1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H22Cl2N2O/c1-13-16(5-4-6-17(13)21)19(24)22-18(11-12-23(2)3)14-7-9-15(20)10-8-14/h4-10,18H,11-12H2,1-3H3,(H,22,24)
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n/an/an/an/a 1.74E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50414760
PNG
(CHEMBL573837)
Show SMILES CO[C@@H](C(=O)N[C@H](CCN(C)C)c1ccc(Cl)cc1)c1ccccc1 |r|
Show InChI InChI=1S/C20H25ClN2O2/c1-23(2)14-13-18(15-9-11-17(21)12-10-15)22-20(24)19(25-3)16-7-5-4-6-8-16/h4-12,18-19H,13-14H2,1-3H3,(H,22,24)/t18-,19-/m1/s1
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n/an/an/an/a 5.01E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475736
PNG
(CHEMBL203528)
Show SMILES CN(C)CCC(OC(=O)Nc1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H25ClN2O2/c1-27(2)17-16-23(20-8-12-21(25)13-9-20)29-24(28)26-22-14-10-19(11-15-22)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3,(H,26,28)
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n/an/an/an/a 269n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475737
PNG
(CHEMBL205991)
Show SMILES CN(C)CCC(OC(=O)c1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H24ClNO2/c1-26(2)17-16-23(20-12-14-22(25)15-13-20)28-24(27)21-10-8-19(9-11-21)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3
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n/an/an/an/a 525n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475738
PNG
(CHEMBL203106)
Show SMILES COc1cccc(NC(=O)NC(CCN(C)C)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C19H24ClN3O2/c1-23(2)12-11-18(14-7-9-15(20)10-8-14)22-19(24)21-16-5-4-6-17(13-16)25-3/h4-10,13,18H,11-12H2,1-3H3,(H2,21,22,24)
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n/an/an/an/a 1.35E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475739
PNG
(CHEMBL207783)
Show SMILES CN(C)CC[C@H](NC(=O)c1ccc2ccccc2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C22H23ClN2O/c1-25(2)14-13-21(17-9-11-20(23)12-10-17)24-22(26)19-8-7-16-5-3-4-6-18(16)15-19/h3-12,15,21H,13-14H2,1-2H3,(H,24,26)/t21-/m0/s1
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n/an/an/an/a 407n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475740
PNG
(CHEMBL377946)
Show SMILES CN(C)CCC(OC(=O)c1cc2ccccc2n1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClN2O2/c1-23(2)13-12-20(15-8-10-17(22)11-9-15)26-21(25)19-14-16-6-4-5-7-18(16)24(19)3/h4-11,14,20H,12-13H2,1-3H3
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n/an/an/an/a 1.38E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475741
PNG
(CHEMBL208512)
Show SMILES CN(C)CCC(OC(=O)c1cccc(C)c1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H24ClNO2/c1-14-6-5-7-18(15(14)2)20(23)24-19(12-13-22(3)4)16-8-10-17(21)11-9-16/h5-11,19H,12-13H2,1-4H3
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n/an/an/an/a 1.15E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475742
PNG
(CHEMBL203531)
Show SMILES COc1ccc(cc1)C(=O)NC(CCN(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O2/c1-22(2)13-12-18(14-4-8-16(20)9-5-14)21-19(23)15-6-10-17(24-3)11-7-15/h4-11,18H,12-13H2,1-3H3,(H,21,23)
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n/an/an/an/a 1.35E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475743
PNG
(CHEMBL204988)
Show SMILES CN(C)CCC(NC(=O)c1ccc(cc1)C(F)(F)F)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClF3N2O/c1-25(2)12-11-17(13-5-9-16(20)10-6-13)24-18(26)14-3-7-15(8-4-14)19(21,22)23/h3-10,17H,11-12H2,1-2H3,(H,24,26)
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n/an/an/an/a 78n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475744
PNG
(CHEMBL206832)
Show SMILES CN(C)CCC(OC(=O)c1cc(C)c(C)cc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H26ClNO2/c1-14-12-16(3)19(13-15(14)2)21(24)25-20(10-11-23(4)5)17-6-8-18(22)9-7-17/h6-9,12-13,20H,10-11H2,1-5H3
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n/an/an/an/a 468n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475745
PNG
(CHEMBL383258)
Show SMILES CN(C)CCC(OC(=O)c1ccc(C)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H22ClNO2/c1-14-4-6-16(7-5-14)19(22)23-18(12-13-21(2)3)15-8-10-17(20)11-9-15/h4-11,18H,12-13H2,1-3H3
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n/an/an/an/a 2.75E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475746
PNG
(CHEMBL378235)
Show SMILES COc1cccc(C(=O)OC(CCN(C)C)c2ccc(Cl)cc2)c1C
Show InChI InChI=1S/C20H24ClNO3/c1-14-17(6-5-7-18(14)24-4)20(23)25-19(12-13-22(2)3)15-8-10-16(21)11-9-15/h5-11,19H,12-13H2,1-4H3
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n/an/an/an/a 1.95E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50414782
PNG
(CHEMBL583981)
Show SMILES CN(C)CCC(NC(=O)c1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H25ClN2O/c1-27(2)17-16-23(20-12-14-22(25)15-13-20)26-24(28)21-10-8-19(9-11-21)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3,(H,26,28)
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n/an/an/an/a 78n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475747
PNG
(CHEMBL383698)
Show SMILES CN(C)CCC(NC(=O)Nc1ccc(Oc2ccccc2)cc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClN3O2/c1-28(2)17-16-23(18-8-10-19(25)11-9-18)27-24(29)26-20-12-14-22(15-13-20)30-21-6-4-3-5-7-21/h3-15,23H,16-17H2,1-2H3,(H2,26,27,29)
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n/an/an/an/a 110n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475748
PNG
(CHEMBL205488)
Show SMILES CN(C)CCC(OC(=O)Nc1ccccc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H23ClN2O2/c1-14-6-4-5-7-17(14)21-19(23)24-18(12-13-22(2)3)15-8-10-16(20)11-9-15/h4-11,18H,12-13H2,1-3H3,(H,21,23)
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n/an/an/an/a 3.89E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475749
PNG
(CHEMBL205628)
Show SMILES CN(C)CCC(NC(=O)c1ccc2OCOc2c1)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H21ClN2O3/c1-22(2)10-9-16(13-3-6-15(20)7-4-13)21-19(23)14-5-8-17-18(11-14)25-12-24-17/h3-8,11,16H,9-10,12H2,1-2H3,(H,21,23)
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n/an/an/an/a 2.14E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50414787
PNG
(CHEMBL573857)
Show SMILES CN(C)CC[C@H](NC(=O)c1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C24H25ClN2O/c1-27(2)17-16-23(20-12-14-22(25)15-13-20)26-24(28)21-10-8-19(9-11-21)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3,(H,26,28)/t23-/m0/s1
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n/an/an/an/a 32n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50414788
PNG
(CHEMBL572699)
Show SMILES CN(C)CC[C@@H](NC(=O)c1ccc(cc1)-c1ccccc1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C24H25ClN2O/c1-27(2)17-16-23(20-12-14-22(25)15-13-20)26-24(28)21-10-8-19(9-11-21)18-6-4-3-5-7-18/h3-15,23H,16-17H2,1-2H3,(H,26,28)/t23-/m1/s1
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n/an/an/an/a 1.45E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
Urotensin-2 receptor


(Homo sapiens (Human))
BDBM50475750
PNG
(CHEMBL204227)
Show SMILES CN(C)CCC(OC(=O)c1cc(C)ccc1C)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H24ClNO2/c1-14-5-6-15(2)18(13-14)20(23)24-19(11-12-22(3)4)16-7-9-17(21)10-8-16/h5-10,13,19H,11-12H2,1-4H3
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n/an/an/an/a 1.86E+3n/an/an/an/a



G£teborg University

Curated by ChEMBL


Assay Description
Activity against human urotensin-2 receptor expressed in NIH3T3 cells


J Med Chem 49: 2232-40 (2006)


Article DOI: 10.1021/jm051121i
BindingDB Entry DOI: 10.7270/Q24Q7XQB
More data for this
Ligand-Target Pair
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