| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urotensin-2 receptor |
|---|
| Ligand | BDBM50475714 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_342488 (CHEMBL861584) |
|---|
| EC50 | 1122±n/a nM |
|---|
| Citation |  Lehmann, F; Pettersen, A; Currier, EA; Sherbukhin, V; Olsson, R; Hacksell, U; Luthman, K Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J Med Chem49:2232-40 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urotensin-2 receptor |
|---|
| Name: | Urotensin-2 receptor |
|---|
| Synonyms: | G-protein coupled receptor 14 | GPR14 | UR-II-R | UR2R_HUMAN | UTS2R | Urotensin II receptor | Urotensin-II |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42159.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Urotensin-II UTS2R HUMAN::Q9UKP6 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSA
MGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGD
VGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLL
TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRR
SQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLT
TCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLS
SCSPQPTDSLVLAPAAPARPAPEGPRAPA
|
|
|
|---|
| BDBM50475714 |
|---|
| n/a |
|---|
| Name | BDBM50475714 |
|---|
| Synonyms: | CHEMBL208536 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H23ClN2O3 |
|---|
| Mol. Mass. | 362.851 |
|---|
| SMILES | COc1cccc(NC(=O)OC(CCN(C)C)c2ccc(Cl)cc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
