| Reaction Details |
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 | Report a problem with these data |
| Target | Urotensin-2 receptor |
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| Ligand | BDBM50475708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_342488 (CHEMBL861584) |
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| EC50 | 117±n/a nM |
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| Citation |  Lehmann, F; Pettersen, A; Currier, EA; Sherbukhin, V; Olsson, R; Hacksell, U; Luthman, K Novel potent and efficacious nonpeptidic urotensin II receptor agonists. J Med Chem49:2232-40 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urotensin-2 receptor |
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| Name: | Urotensin-2 receptor |
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| Synonyms: | G-protein coupled receptor 14 | GPR14 | UR-II-R | UR2R_HUMAN | UTS2R | Urotensin II receptor | Urotensin-II |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42159.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Urotensin-II UTS2R HUMAN::Q9UKP6 |
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| Residue: | 389 |
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| Sequence: | MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSA
MGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGD
VGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLL
TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRR
SQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLT
TCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLS
SCSPQPTDSLVLAPAAPARPAPEGPRAPA
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| BDBM50475708 |
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| n/a |
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| Name | BDBM50475708 |
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| Synonyms: | CHEMBL425592 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClF3N3O |
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| Mol. Mass. | 399.838 |
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| SMILES | CN(C)CCC(NC(=O)Nc1ccc(cc1)C(F)(F)F)c1ccc(Cl)cc1 |
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| Structure | 
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