Compile Data Set for Download or QSAR

Found 19 hits Enz. Inhib. hit(s) with all data for entry = 50006280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498433 (CHEMBL3593892) Show SMILES c1ccncc1.[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OS(O)(=O)=O)[C@H](C)CC |r| Show InChI InChI=1S/C23H40O4S.C5H5N/c1-5-15(2)19-8-9-20-18-7-6-16-14-17(27-28(24,25)26)10-12-22(16,3)21(18)11-13-23(19,20)4;1-2-4-6-5-3-1/h15-21H,5-14H2,1-4H3,(H,24,25,26);1-5H/t15-,16-,17-,18+,19-,20+,21+,22+,23-;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498431 (CHEMBL3594108) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C22H38O4S.C5H5N/c1-14(2)18-7-8-19-17-6-5-15-13-16(26-27(23,24)25)9-11-21(15,3)20(17)10-12-22(18,19)4;1-2-4-6-5-3-1/h14-20H,5-13H2,1-4H3,(H,23,24,25);1-5H/t15-,16-,17+,18-,19+,20+,21+,22-;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (Homo sapiens (Human))	BDBM50498430 (CHEMBL3594112) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h13-18H,4-12H2,1-3H3,(H,21,22,23);1-5H/t13-,14+,15+,16-,17-,18-,19+,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2C receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498443 (CHEMBL3594106) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](CC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C21H36O4S.C5H5N/c1-4-14-6-8-18-17-7-5-15-13-16(25-26(22,23)24)9-11-21(15,3)19(17)10-12-20(14,18)2;1-2-4-6-5-3-1/h14-19H,4-13H2,1-3H3,(H,22,23,24);1-5H/t14-,15+,16+,17-,18-,19-,20+,21-;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (Homo sapiens (Human))	BDBM50498430 (CHEMBL3594112) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h13-18H,4-12H2,1-3H3,(H,21,22,23);1-5H/t13-,14+,15+,16-,17-,18-,19+,20-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2D receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498440 (CHEMBL3594107) Show SMILES c1ccncc1.[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OS(O)(=O)=O)C(C)=C |r| Show InChI InChI=1S/C22H36O4S.C5H5N/c1-14(2)18-7-8-19-17-6-5-15-13-16(26-27(23,24)25)9-11-21(15,3)20(17)10-12-22(18,19)4;1-2-4-6-5-3-1/h15-20H,1,5-13H2,2-4H3,(H,23,24,25);1-5H/t15-,16-,17+,18-,19+,20+,21+,22-;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Homo sapiens (Human))	BDBM50498430 (CHEMBL3594112) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h13-18H,4-12H2,1-3H3,(H,21,22,23);1-5H/t13-,14+,15+,16-,17-,18-,19+,20-;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498430 (CHEMBL3594112) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h13-18H,4-12H2,1-3H3,(H,21,22,23);1-5H/t13-,14+,15+,16-,17-,18-,19+,20-;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498445 (CHEMBL3594109) Show SMILES c1ccncc1.[H][C@@]12CC[C@H](I)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C19H31IO4S.C5H5N/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18;1-2-4-6-5-3-1/h12-17H,3-11H2,1-2H3,(H,21,22,23);1-5H/t12-,13-,14+,15+,16+,17+,18+,19+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498441 (CHEMBL3594117) Show SMILES c1ccncc1.[H][C@]12CC[C@@]3([H])[C@@]([H])(CC[C@]4([H])C[C@@H](CC[C@]34C)OS(O)(=O)=O)[C@]1([H])CC[C@@H]2C |r| Show InChI InChI=1S/C19H32O4S.C5H5N/c1-12-3-5-16-15(12)7-8-18-17(16)6-4-13-11-14(23-24(20,21)22)9-10-19(13,18)2;1-2-4-6-5-3-1/h12-18H,3-11H2,1-2H3,(H,20,21,22);1-5H/t12-,13+,14+,15+,16+,17-,18-,19-;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498432 (CHEMBL3594113) Show SMILES c1ccncc1.[H][C@@]12CC\C(=C\C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C21H34O4S.C5H5N/c1-4-14-6-8-18-17-7-5-15-13-16(25-26(22,23)24)9-11-21(15,3)19(17)10-12-20(14,18)2;1-2-4-6-5-3-1/h4,15-19H,5-13H2,1-3H3,(H,22,23,24);1-5H/b14-4-;/t15-,16-,17+,18+,19+,20-,21+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498436 (CHEMBL3594116) Show SMILES c1ccncc1.[H][C@@]12CC[C@@]3([H])[C@@]([H])(CC[C@]4([H])C[C@@H](CC[C@]34C)OS(O)(=O)=O)[C@]1([H])CC[C@H]2C |r| Show InChI InChI=1S/C19H32O4S.C5H5N/c1-12-3-5-16-15(12)7-8-18-17(16)6-4-13-11-14(23-24(20,21)22)9-10-19(13,18)2;1-2-4-6-5-3-1/h12-18H,3-11H2,1-2H3,(H,20,21,22);1-5H/t12-,13-,14-,15+,16-,17+,18+,19+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498437 (CHEMBL3594115) Show SMILES c1ccncc1.[H][C@]12CC[C@@]3([H])[C@]4([H])CCCC[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@H](C2)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H34O4S.C5H5N/c1-19-10-4-3-5-17(19)16-7-6-14-13-15(24-25(21,22)23)8-12-20(14,2)18(16)9-11-19;1-2-4-6-5-3-1/h14-18H,3-13H2,1-2H3,(H,21,22,23);1-5H/t14-,15-,16+,17+,18+,19+,20+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498444 (CHEMBL3594110) Show SMILES c1ccncc1.[H][C@@]12CCC[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C19H32O4S.C5H5N/c1-18-9-3-4-16(18)15-6-5-13-12-14(23-24(20,21)22)7-11-19(13,2)17(15)8-10-18;1-2-4-6-5-3-1/h13-17H,3-12H2,1-2H3,(H,20,21,22);1-5H/t13-,14-,15+,16+,17+,18+,19+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498438 (CHEMBL3594111) Show SMILES c1ccncc1.[H][C@@]12CCC(=C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H32O4S.C5H5N/c1-13-4-7-17-16-6-5-14-12-15(24-25(21,22)23)8-10-20(14,3)18(16)9-11-19(13,17)2;1-2-4-6-5-3-1/h14-18H,1,4-12H2,2-3H3,(H,21,22,23);1-5H/t14-,15-,16+,17+,18+,19-,20+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498435 (CHEMBL3594118) Show SMILES c1ccncc1.[H][C@@]12CC(=C)C[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C20H32O4S.C5H5N/c1-13-10-18-16-5-4-14-11-15(24-25(21,22)23)6-9-20(14,3)17(16)7-8-19(18,2)12-13;1-2-4-6-5-3-1/h14-18H,1,4-12H2,2-3H3,(H,21,22,23);1-5H/t14-,15-,16-,17+,18+,19-,20+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498434 (CHEMBL3594120) Show SMILES c1ccncc1.[H][C@@]12CCC[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12[H])OS(O)(=O)=O |r| Show InChI InChI=1S/C18H30O4S.C5H5N/c1-18-9-2-3-17(18)16-6-4-12-11-13(22-23(19,20)21)5-7-14(12)15(16)8-10-18;1-2-4-6-5-3-1/h12-17H,2-11H2,1H3,(H,19,20,21);1-5H/t12-,13-,14+,15-,16-,17+,18+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498442 (CHEMBL3594114) Show SMILES c1ccncc1.[H][C@@]12CCC(F)(F)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C19H30F2O4S.C5H5N/c1-17-8-5-13(25-26(22,23)24)11-12(17)3-4-14-15(17)6-9-18(2)16(14)7-10-19(18,20)21;1-2-4-6-5-3-1/h12-16H,3-11H2,1-2H3,(H,22,23,24);1-5H/t12-,13-,14-,15+,16+,17+,18+;/m1./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50498439 (CHEMBL1179566) Show SMILES [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)OS(O)(=O)=O |r| Show InChI InChI=1S/C21H34O5S/c1-13(22)17-6-7-18-16-5-4-14-12-15(26-27(23,24)25)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19H,4-12H2,1-3H3,(H,23,24,25)/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic v.v.i. Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...				J Med Chem 58: 5950-66 (2015) Article DOI: 10.1021/acs.jmedchem.5b00570 BindingDB Entry DOI: 10.7270/Q2959MKM
					More data for this Ligand-Target Pair