Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM8125 ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.0160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498806 (CHEMBL3627879) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171372 (US9085571, Table 1, Compound 20) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498808 (CHEMBL3627874) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498814 (CHEMBL3627876) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171370 (US9085571, Table 1, Compound 18) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498812 (CHEMBL3627855) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498807 (CHEMBL3627856) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171371 (US9085571, Table 1, Compound 19) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498813 (CHEMBL3627875) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498810 (CHEMBL3627857) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498809 (CHEMBL3627852) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171367 (US9085571, Table 1, Compound 15) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171369 (US9085571, Table 1, Compound 17) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50498811 (CHEMBL3627851) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM171362 (US9085571, Table 1, Compound 10) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of HIV-1 protease by fluorometric assay | Bioorg Med Chem Lett 25: 4903-4909 (2015) Article DOI: 10.1016/j.bmcl.2015.05.052 BindingDB Entry DOI: 10.7270/Q2P84FW4 | |||||||||||
More data for this Ligand-Target Pair |