BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with all data for entry = 50007414
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062823 (6-(4-Fluoro-benzyloxy)-5-nitroso-pyrimidine-2,4-di...) Show SMILES Nc1nc(N)c(N=O)c(OCc2ccc(F)cc2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM5573 (6-(benzyloxy)-5-nitrosopyrimidine-2,4-diamine \| CH...) Show SMILES Nc1nc(N)c(N=O)c(OCc2ccccc2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062816 (5-Nitroso-6-(pyridin-4-ylmethoxy)-pyrimidine-2,4-d...) Show SMILES Nc1nc(N)c(N=O)c(OCc2ccncc2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062815 (6-(4-Fluoro-benzyloxy)-5-nitro-pyrimidine-2,4-diam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062813 (6-Benzyloxy-5-nitro-pyrimidine-2,4-diamine \| CHEMB...) Show SMILES Nc1nc(N)c(c(OCc2ccccc2)n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062819 (5-Nitro-6-(pyridin-3-ylmethoxy)-pyrimidine-2,4-dia...) Show SMILES Nc1nc(N)c(c(OCc2cccnc2)n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062818 (5-Nitro-6-(pyridin-4-ylmethoxy)-pyrimidine-2,4-dia...) Show SMILES Nc1nc(N)c(c(OCc2ccncc2)n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062817 (6-(3-Fluoro-benzyloxy)-5-nitro-pyrimidine-2,4-diam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM5491 (6-(benzyloxy)-9H-purin-2-amine \| CHEMBL407874 \| O6...) Show SMILES Nc1nc(OCc2ccccc2)c2[nH]cnc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062822 (6-(2-Fluoro-benzyloxy)-5-nitro-pyrimidine-2,4-diam...) Show SMILES Nc1nc(N)c(c(OCc2ccccc2F)n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062814 (5-Nitro-6-(pyridin-2-ylmethoxy)-pyrimidine-2,4-dia...) Show SMILES Nc1nc(N)c(c(OCc2ccccn2)n1)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair
Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens (Human))	BDBM50062821 (6-Benzyloxy-pyrimidine-2,4-diamine \| CHEMBL121445) Show SMILES Nc1cc(OCc2ccccc2)nc(N)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University Curated by ChEMBL					Assay Description In vitro inhibitory activity against human O6-alkylguanine-DNA alkyltransferase (AGAT)				J Med Chem 41: 503-8 (1998) Article DOI: 10.1021/jm970363i BindingDB Entry DOI: 10.7270/Q21G0KD5
Nagoya City University Curated by ChEMBL					More data for this Ligand-Target Pair