Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with all data for entry = 50007657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511334 (CHEMBL4557553) Show SMILES COC(=O)c1ccc(CNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C24H19FN2O4S/c1-30-23(29)16-8-6-15(7-9-16)14-26-22(28)12-17-10-11-18(13-19(17)25)31-24-27-20-4-2-3-5-21(20)32-24/h2-11,13H,12,14H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511340 (CHEMBL4471473) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2)cc1 Show InChI InChI=1S/C23H19FN2O2S/c24-18-9-5-16(6-10-18)13-14-25-22(27)15-17-7-11-19(12-8-17)28-23-26-20-3-1-2-4-21(20)29-23/h1-12H,13-15H2,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511324 (CHEMBL4529780) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-8-5-15(6-9-17)11-12-26-22(28)13-16-7-10-18(14-19(16)25)29-23-27-20-3-1-2-4-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511330 (CHEMBL4463223) Show SMILES Fc1ccc(CCNCc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C21H20FNO/c22-19-10-6-17(7-11-19)14-15-23-16-18-8-12-21(13-9-18)24-20-4-2-1-3-5-20/h1-13,23H,14-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511328 (CHEMBL4531314) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H20FNO2/c23-19-10-6-17(7-11-19)14-15-24-22(25)16-18-8-12-21(13-9-18)26-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511327 (CHEMBL4536499) Show SMILES FC(F)(F)c1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO2/c24-23(25,26)19-10-6-17(7-11-19)14-15-27-22(28)16-18-8-12-21(13-9-18)29-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511340 (CHEMBL4471473) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2)cc1 Show InChI InChI=1S/C23H19FN2O2S/c24-18-9-5-16(6-10-18)13-14-25-22(27)15-17-7-11-19(12-8-17)28-23-26-20-3-1-2-4-21(20)29-23/h1-12H,13-15H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511325 (CHEMBL4475844) Show SMILES FC(F)(F)Oc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO3/c24-23(25,26)30-21-12-6-17(7-13-21)14-15-27-22(28)16-18-8-10-20(11-9-18)29-19-4-2-1-3-5-19/h1-13H,14-16H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511324 (CHEMBL4529780) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-8-5-15(6-9-17)11-12-26-22(28)13-16-7-10-18(14-19(16)25)29-23-27-20-3-1-2-4-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511339 (CHEMBL4574175) Show SMILES Fc1cccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)c1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-5-3-4-15(12-17)10-11-26-22(28)13-16-8-9-18(14-19(16)25)29-23-27-20-6-1-2-7-21(20)30-23/h1-9,12,14H,10-11,13H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511329 (CHEMBL4461553) Show SMILES Clc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H20ClNO2/c23-19-10-6-17(7-11-19)14-15-24-22(25)16-18-8-12-21(13-9-18)26-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511327 (CHEMBL4536499) Show SMILES FC(F)(F)c1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO2/c24-23(25,26)19-10-6-17(7-11-19)14-15-27-22(28)16-18-8-12-21(13-9-18)29-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511325 (CHEMBL4475844) Show SMILES FC(F)(F)Oc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H20F3NO3/c24-23(25,26)30-21-12-6-17(7-13-21)14-15-27-22(28)16-18-8-10-20(11-9-18)29-19-4-2-1-3-5-19/h1-13H,14-16H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511333 (CHEMBL4548077) Show SMILES Fc1ccccc1CCNC(=O)Cc1ccc(Oc2nc3ccccc3s2)cc1F Show InChI InChI=1S/C23H18F2N2O2S/c24-18-6-2-1-5-15(18)11-12-26-22(28)13-16-9-10-17(14-19(16)25)29-23-27-20-7-3-4-8-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511331 (CHEMBL4440564) Show SMILES Fc1ccc(CCNC(=O)CCc2ccc(OCc3ccncc3)cc2)cc1 Show InChI InChI=1S/C23H23FN2O2/c24-21-6-1-19(2-7-21)13-16-26-23(27)10-5-18-3-8-22(9-4-18)28-17-20-11-14-25-15-12-20/h1-4,6-9,11-12,14-15H,5,10,13,16-17H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511335 (CHEMBL4439245) Show SMILES Fc1ccc2c(CNC(=O)Cc3ccc(Oc4nc5ccccc5s4)cc3F)c[nH]c2c1 Show InChI InChI=1S/C24H17F2N3O2S/c25-16-6-8-18-15(12-27-21(18)10-16)13-28-23(30)9-14-5-7-17(11-19(14)26)31-24-29-20-3-1-2-4-22(20)32-24/h1-8,10-12,27H,9,13H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511328 (CHEMBL4531314) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H20FNO2/c23-19-10-6-17(7-11-19)14-15-24-22(25)16-18-8-12-21(13-9-18)26-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511336 (CHEMBL4575840) Show SMILES Cc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H23NO2/c1-18-7-9-19(10-8-18)15-16-24-23(25)17-20-11-13-22(14-12-20)26-21-5-3-2-4-6-21/h2-14H,15-17H2,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511339 (CHEMBL4574175) Show SMILES Fc1cccc(CCNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)c1 Show InChI InChI=1S/C23H18F2N2O2S/c24-17-5-3-4-15(12-17)10-11-26-22(28)13-16-8-9-18(14-19(16)25)29-23-27-20-6-1-2-7-21(20)30-23/h1-9,12,14H,10-11,13H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511326 (CHEMBL4451563) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4cc(ccc4s3)C(F)(F)F)cc2F)cc1 Show InChI InChI=1S/C24H17F5N2O2S/c25-17-5-1-14(2-6-17)9-10-30-22(32)11-15-3-7-18(13-19(15)26)33-23-31-20-12-16(24(27,28)29)4-8-21(20)34-23/h1-8,12-13H,9-11H2,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511329 (CHEMBL4461553) Show SMILES Clc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C22H20ClNO2/c23-19-10-6-17(7-11-19)14-15-24-22(25)16-18-8-12-21(13-9-18)26-20-4-2-1-3-5-20/h1-13H,14-16H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511330 (CHEMBL4463223) Show SMILES Fc1ccc(CCNCc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C21H20FNO/c22-19-10-6-17(7-11-19)14-15-23-16-18-8-12-21(13-9-18)24-20-4-2-1-3-5-20/h1-13,23H,14-16H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511333 (CHEMBL4548077) Show SMILES Fc1ccccc1CCNC(=O)Cc1ccc(Oc2nc3ccccc3s2)cc1F Show InChI InChI=1S/C23H18F2N2O2S/c24-18-6-2-1-5-15(18)11-12-26-22(28)13-16-9-10-17(14-19(16)25)29-23-27-20-7-3-4-8-21(20)30-23/h1-10,14H,11-13H2,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511335 (CHEMBL4439245) Show SMILES Fc1ccc2c(CNC(=O)Cc3ccc(Oc4nc5ccccc5s4)cc3F)c[nH]c2c1 Show InChI InChI=1S/C24H17F2N3O2S/c25-16-6-8-18-15(12-27-21(18)10-16)13-28-23(30)9-14-5-7-17(11-19(14)26)31-24-29-20-3-1-2-4-22(20)32-24/h1-8,10-12,27H,9,13H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511332 (CHEMBL4572731) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccc(cc4s3)C(F)(F)F)cc2F)cc1 Show InChI InChI=1S/C24H17F5N2O2S/c25-17-5-1-14(2-6-17)9-10-30-22(32)11-15-3-7-18(13-19(15)26)33-23-31-20-8-4-16(24(27,28)29)12-21(20)34-23/h1-8,12-13H,9-11H2,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511338 (CHEMBL4537609) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4cc(F)ccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H17F3N2O2S/c24-16-4-1-14(2-5-16)9-10-27-22(29)11-15-3-7-18(13-19(15)26)30-23-28-20-12-17(25)6-8-21(20)31-23/h1-8,12-13H,9-11H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50511337 (CHEMBL4464257) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccc(F)cc4s3)cc2F)cc1 Show InChI InChI=1S/C23H17F3N2O2S/c24-16-4-1-14(2-5-16)9-10-27-22(29)11-15-3-7-18(13-19(15)26)30-23-28-20-8-6-17(25)12-21(20)31-23/h1-8,12-13H,9-11H2,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of full length human soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluorescent PHOME as ...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511326 (CHEMBL4451563) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4cc(ccc4s3)C(F)(F)F)cc2F)cc1 Show InChI InChI=1S/C24H17F5N2O2S/c25-17-5-1-14(2-6-17)9-10-30-22(32)11-15-3-7-18(13-19(15)26)33-23-31-20-12-16(24(27,28)29)4-8-21(20)34-23/h1-8,12-13H,9-11H2,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511334 (CHEMBL4557553) Show SMILES COC(=O)c1ccc(CNC(=O)Cc2ccc(Oc3nc4ccccc4s3)cc2F)cc1 Show InChI InChI=1S/C24H19FN2O4S/c1-30-23(29)16-8-6-15(7-9-16)14-26-22(28)12-17-10-11-18(13-19(17)25)31-24-27-20-4-2-3-5-21(20)32-24/h2-11,13H,12,14H2,1H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511331 (CHEMBL4440564) Show SMILES Fc1ccc(CCNC(=O)CCc2ccc(OCc3ccncc3)cc2)cc1 Show InChI InChI=1S/C23H23FN2O2/c24-21-6-1-19(2-7-21)13-16-26-23(27)10-5-18-3-8-22(9-4-18)28-17-20-11-14-25-15-12-20/h1-4,6-9,11-12,14-15H,5,10,13,16-17H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511337 (CHEMBL4464257) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccc(F)cc4s3)cc2F)cc1 Show InChI InChI=1S/C23H17F3N2O2S/c24-16-4-1-14(2-5-16)9-10-27-22(29)11-15-3-7-18(13-19(15)26)30-23-28-20-8-6-17(25)12-21(20)31-23/h1-8,12-13H,9-11H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511332 (CHEMBL4572731) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4ccc(cc4s3)C(F)(F)F)cc2F)cc1 Show InChI InChI=1S/C24H17F5N2O2S/c25-17-5-1-14(2-6-17)9-10-30-22(32)11-15-3-7-18(13-19(15)26)33-23-31-20-8-4-16(24(27,28)29)12-21(20)34-23/h1-8,12-13H,9-11H2,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511338 (CHEMBL4537609) Show SMILES Fc1ccc(CCNC(=O)Cc2ccc(Oc3nc4cc(F)ccc4s3)cc2F)cc1 Show InChI InChI=1S/C23H17F3N2O2S/c24-16-4-1-14(2-5-16)9-10-27-22(29)11-15-3-7-18(13-19(15)26)30-23-28-20-12-17(25)6-8-21(20)31-23/h1-8,12-13H,9-11H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50511336 (CHEMBL4575840) Show SMILES Cc1ccc(CCNC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C23H23NO2/c1-18-7-9-19(10-8-18)15-16-24-23(25)17-20-11-13-22(14-12-20)26-21-5-3-2-4-6-21/h2-14H,15-17H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Inhibition of (His)6 tagged human recombinant LTA4H expressed in Escherichia coli BL21(DE3) using non-fluorescent L-arginine-7-amino-4-methylcoumarin...				ACS Med Chem Lett 11: 298-302 (2020) Article DOI: 10.1021/acsmedchemlett.9b00330 BindingDB Entry DOI: 10.7270/Q2M3303Q
					More data for this Ligand-Target Pair