Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50008064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50070409 (2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4[nH]cc(CCN)c4c3)cc12 Show InChI InChI=1S/C27H32N4O2/c1-30-11-13-31(14-12-30)27-4-2-3-20-5-6-22(18-25(20)27)32-15-16-33-23-7-8-26-24(17-23)21(9-10-28)19-29-26/h2-8,17-19,29H,9-16,28H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50070406 (2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)Nc3ccc(NC(=O)COc4ccc5[nH]cc(CCN)c5c4)cc3)cc12 Show InChI InChI=1S/C35H38N6O4/c1-40-15-17-41(18-16-40)33-4-2-3-24-5-10-28(20-31(24)33)44-22-34(42)38-26-6-8-27(9-7-26)39-35(43)23-45-29-11-12-32-30(19-29)25(13-14-36)21-37-32/h2-12,19-21,37H,13-18,22-23,36H2,1H3,(H,38,42)(H,39,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070406 (2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)Nc3ccc(NC(=O)COc4ccc5[nH]cc(CCN)c5c4)cc3)cc12 Show InChI InChI=1S/C35H38N6O4/c1-40-15-17-41(18-16-40)33-4-2-3-24-5-10-28(20-31(24)33)44-22-34(42)38-26-6-8-27(9-7-26)39-35(43)23-45-29-11-12-32-30(19-29)25(13-14-36)21-37-32/h2-12,19-21,37H,13-18,22-23,36H2,1H3,(H,38,42)(H,39,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070409 (2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4[nH]cc(CCN)c4c3)cc12 Show InChI InChI=1S/C27H32N4O2/c1-30-11-13-31(14-12-30)27-4-2-3-20-5-6-22(18-25(20)27)32-15-16-33-23-7-8-26-24(17-23)21(9-10-28)19-29-26/h2-8,17-19,29H,9-16,28H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070409 (2-(5-(2-(8-(4-methylpiperazin-1-yl)naphthalen-2-yl...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4[nH]cc(CCN)c4c3)cc12 Show InChI InChI=1S/C27H32N4O2/c1-30-11-13-31(14-12-30)27-4-2-3-20-5-6-22(18-25(20)27)32-15-16-33-23-7-8-26-24(17-23)21(9-10-28)19-29-26/h2-8,17-19,29H,9-16,28H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50070408 (2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)C(=O)COc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C38H46N6O4/c1-39-13-17-41(18-14-39)35-7-3-5-29-9-11-31(25-33(29)35)47-27-37(45)43-21-23-44(24-22-43)38(46)28-48-32-12-10-30-6-4-8-36(34(30)26-32)42-19-15-40(2)16-20-42/h3-12,25-26H,13-24,27-28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50070405 (1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C32H38N4O2/c1-33-13-17-35(18-14-33)31-7-3-5-25-9-11-27(23-29(25)31)37-21-22-38-28-12-10-26-6-4-8-32(30(26)24-28)36-19-15-34(2)16-20-36/h3-12,23-24H,13-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070405 (1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C32H38N4O2/c1-33-13-17-35(18-14-33)31-7-3-5-25-9-11-27(23-29(25)31)37-21-22-38-28-12-10-26-6-4-8-32(30(26)24-28)36-19-15-34(2)16-20-36/h3-12,23-24H,13-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070408 (2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)C(=O)COc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C38H46N6O4/c1-39-13-17-41(18-14-39)35-7-3-5-29-9-11-31(25-33(29)35)47-27-37(45)43-21-23-44(24-22-43)38(46)28-48-32-12-10-30-6-4-8-36(34(30)26-32)42-19-15-40(2)16-20-42/h3-12,25-26H,13-24,27-28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50070407 (2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...) Show SMILES CCCN(CCC)C1CCc2cccc(OCCCCCCOc3cccc4CCC(Cc34)N(CCC)CCC)c2C1 Show InChI InChI=1S/C38H60N2O2/c1-5-23-39(24-6-2)33-21-19-31-15-13-17-37(35(31)29-33)41-27-11-9-10-12-28-42-38-18-14-16-32-20-22-34(30-36(32)38)40(25-7-3)26-8-4/h13-18,33-34H,5-12,19-30H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070408 (2-[8-(4-Methyl-piperazin-1-yl)-naphthalen-2-yloxy]...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)C(=O)COc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C38H46N6O4/c1-39-13-17-41(18-14-39)35-7-3-5-29-9-11-31(25-33(29)35)47-27-37(45)43-21-23-44(24-22-43)38(46)28-48-32-12-10-30-6-4-8-36(34(30)26-32)42-19-15-40(2)16-20-42/h3-12,25-26H,13-24,27-28H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070406 (2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[8-...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)Nc3ccc(NC(=O)COc4ccc5[nH]cc(CCN)c5c4)cc3)cc12 Show InChI InChI=1S/C35H38N6O4/c1-40-15-17-41(18-16-40)33-4-2-3-24-5-10-28(20-31(24)33)44-22-34(42)38-26-6-8-27(9-7-26)39-35(43)23-45-29-11-12-32-30(19-29)25(13-14-36)21-37-32/h2-12,19-21,37H,13-18,22-23,36H2,1H3,(H,38,42)(H,39,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50007407 (1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...) Show SMILES C1CN(CCN1)c1cccc2ccccc12 Show InChI InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070407 (2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...) Show SMILES CCCN(CCC)C1CCc2cccc(OCCCCCCOc3cccc4CCC(Cc34)N(CCC)CCC)c2C1 Show InChI InChI=1S/C38H60N2O2/c1-5-23-39(24-6-2)33-21-19-31-15-13-17-37(35(31)29-33)41-27-11-9-10-12-28-42-38-18-14-16-32-20-22-34(30-36(32)38)40(25-7-3)26-8-4/h13-18,33-34H,5-12,19-30H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070407 (2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...) Show SMILES CCCN(CCC)C1CCc2cccc(OCCCCCCOc3cccc4CCC(Cc34)N(CCC)CCC)c2C1 Show InChI InChI=1S/C38H60N2O2/c1-5-23-39(24-6-2)33-21-19-31-15-13-17-37(35(31)29-33)41-27-11-9-10-12-28-42-38-18-14-16-32-20-22-34(30-36(32)38)40(25-7-3)26-8-4/h13-18,33-34H,5-12,19-30H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50007407 (1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...) Show SMILES C1CN(CCN1)c1cccc2ccccc12 Show InChI InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50007407 (1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...) Show SMILES C1CN(CCN1)c1cccc2ccccc12 Show InChI InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50070405 (1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C32H38N4O2/c1-33-13-17-35(18-14-33)31-7-3-5-25-9-11-27(23-29(25)31)37-21-22-38-28-12-10-26-6-4-8-32(30(26)24-28)36-19-15-34(2)16-20-36/h3-12,23-24H,13-22H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1D receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	559	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070405 (1,2-di[8-(4-methylhexahydro-1-pyrazinyl)-2-naphthy...) Show SMILES CN1CCN(CC1)c1cccc2ccc(OCCOc3ccc4cccc(N5CCN(C)CC5)c4c3)cc12 Show InChI InChI=1S/C32H38N4O2/c1-33-13-17-35(18-14-33)31-7-3-5-25-9-11-27(23-29(25)31)37-21-22-38-28-12-10-26-6-4-8-32(30(26)24-28)36-19-15-34(2)16-20-36/h3-12,23-24H,13-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50007407 (1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...) Show SMILES C1CN(CCN1)c1cccc2ccccc12 Show InChI InChI=1S/C14H16N2/c1-2-6-13-12(4-1)5-3-7-14(13)16-10-8-15-9-11-16/h1-7,15H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound was evaluated at human recombinant 5-hydroxytryptamine 1B receptor using [3H]-5-CT as radioligand				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50070407 (2N,2N-dipropyl-8-[6-(3-dipropylamino-1,2,3,4-tetra...) Show SMILES CCCN(CCC)C1CCc2cccc(OCCCCCCOc3cccc4CCC(Cc34)N(CCC)CCC)c2C1 Show InChI InChI=1S/C38H60N2O2/c1-5-23-39(24-6-2)33-21-19-31-15-13-17-37(35(31)29-33)41-27-11-9-10-12-28-42-38-18-14-16-32-20-22-34(30-36(32)38)40(25-7-3)26-8-4/h13-18,33-34H,5-12,19-30H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description The intrinsic activity of the compound was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryp...				Bioorg Med Chem Lett 8: 1407-12 (1999) BindingDB Entry DOI: 10.7270/Q2SQ8ZJS
					More data for this Ligand-Target Pair