Found 37 hits Enz. Inhib. hit(s) with all data for entry = 50008303 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072292
![PNG](/data/jpeg/tenK5007/BindingDB_50072292.png) ((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072285
![PNG](/data/jpeg/tenK5007/BindingDB_50072285.png) ((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072289
![PNG](/data/jpeg/tenK5007/BindingDB_50072289.png) ((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6@H]-1-[#6@H]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#8]-[#6]-1=O Show InChI InChI=1S/C13H18O3/c1-8(2)6-9(14)7-11-10-4-3-5-12(10)16-13(11)15/h6,10-12H,3-5,7H2,1-2H3/t10-,11+,12+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072283
![PNG](/data/jpeg/tenK5007/BindingDB_50072283.png) ((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12+,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072286
![PNG](/data/jpeg/tenK5007/BindingDB_50072286.png) ((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072284
![PNG](/data/jpeg/tenK5007/BindingDB_50072284.png) ((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)Show SMILES [H][C@@]12[#6]-[#6][C@]3([#6])[C@@]4([H])[#6]-[#6][C@@]5([#6])[C@]6([H])[#6@@H](-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)-[#8][C@@]6([H])[#6][C@]5([#6])[#6]4=[#6]-[#6][C@@]3([H])[C@]1([#6])[#6](=O)-[#8]2 |r,c:33| Show InChI InChI=1S/C30H40O5/c1-16(2)13-17(31)14-18-24-21(34-25(18)32)15-29(5)20-7-8-22-27(3,19(20)9-12-28(24,29)4)11-10-23-30(22,6)26(33)35-23/h7,13,18-19,21-24H,8-12,14-15H2,1-6H3/t18-,19+,21+,22-,23-,24-,27-,28+,29-,30+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072285
![PNG](/data/jpeg/tenK5007/BindingDB_50072285.png) ((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072290
![PNG](/data/jpeg/tenK5007/BindingDB_50072290.png) ((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8+,9+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072292
![PNG](/data/jpeg/tenK5007/BindingDB_50072292.png) ((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072287
![PNG](/data/jpeg/tenK5007/BindingDB_50072287.png) ((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6@H]-1-[#6]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#8]-[#6]-1=O Show InChI InChI=1S/C13H18O3/c1-8(2)6-9(14)7-11-10-4-3-5-12(10)16-13(11)15/h6,10-12H,3-5,7H2,1-2H3/t10?,11-,12-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072289
![PNG](/data/jpeg/tenK5007/BindingDB_50072289.png) ((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6@H]-1-[#6@H]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#8]-[#6]-1=O Show InChI InChI=1S/C13H18O3/c1-8(2)6-9(14)7-11-10-4-3-5-12(10)16-13(11)15/h6,10-12H,3-5,7H2,1-2H3/t10-,11+,12+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072290
![PNG](/data/jpeg/tenK5007/BindingDB_50072290.png) ((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8+,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072287
![PNG](/data/jpeg/tenK5007/BindingDB_50072287.png) ((3S,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahydro-...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6@H]-1-[#6]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#8]-[#6]-1=O Show InChI InChI=1S/C13H18O3/c1-8(2)6-9(14)7-11-10-4-3-5-12(10)16-13(11)15/h6,10-12H,3-5,7H2,1-2H3/t10?,11-,12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072282
![PNG](/data/jpeg/tenK5007/BindingDB_50072282.png) ((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8-,9+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072293
![PNG](/data/jpeg/tenK5007/BindingDB_50072293.png) (5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C12H20N2O2/c13-11(14)7-2-1-4-9-8-5-3-6-10(8)16-12(9)15/h8-10H,1-7H2,(H3,13,14)/t8-,9-,10+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072282
![PNG](/data/jpeg/tenK5007/BindingDB_50072282.png) ((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8-,9+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072282
![PNG](/data/jpeg/tenK5007/BindingDB_50072282.png) ((3R,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8-,9+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072284
![PNG](/data/jpeg/tenK5007/BindingDB_50072284.png) ((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)Show SMILES [H][C@@]12[#6]-[#6][C@]3([#6])[C@@]4([H])[#6]-[#6][C@@]5([#6])[C@]6([H])[#6@@H](-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)-[#8][C@@]6([H])[#6][C@]5([#6])[#6]4=[#6]-[#6][C@@]3([H])[C@]1([#6])[#6](=O)-[#8]2 |r,c:33| Show InChI InChI=1S/C30H40O5/c1-16(2)13-17(31)14-18-24-21(34-25(18)32)15-29(5)20-7-8-22-27(3,19(20)9-12-28(24,29)4)11-10-23-30(22,6)26(33)35-23/h7,13,18-19,21-24H,8-12,14-15H2,1-6H3/t18-,19+,21+,22-,23-,24-,27-,28+,29-,30+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072284
![PNG](/data/jpeg/tenK5007/BindingDB_50072284.png) ((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)Show SMILES [H][C@@]12[#6]-[#6][C@]3([#6])[C@@]4([H])[#6]-[#6][C@@]5([#6])[C@]6([H])[#6@@H](-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)-[#8][C@@]6([H])[#6][C@]5([#6])[#6]4=[#6]-[#6][C@@]3([H])[C@]1([#6])[#6](=O)-[#8]2 |r,c:33| Show InChI InChI=1S/C30H40O5/c1-16(2)13-17(31)14-18-24-21(34-25(18)32)15-29(5)20-7-8-22-27(3,19(20)9-12-28(24,29)4)11-10-23-30(22,6)26(33)35-23/h7,13,18-19,21-24H,8-12,14-15H2,1-6H3/t18-,19+,21+,22-,23-,24-,27-,28+,29-,30+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Coagulation factor X |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072283
![PNG](/data/jpeg/tenK5007/BindingDB_50072283.png) ((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12+,13+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072286
![PNG](/data/jpeg/tenK5007/BindingDB_50072286.png) ((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12-,13+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072290
![PNG](/data/jpeg/tenK5007/BindingDB_50072290.png) ((3S,3aR,6aS)-3-Allyl-hexahydro-cyclopenta[b]furan-...)Show InChI InChI=1S/C10H14O2/c1-2-4-8-7-5-3-6-9(7)12-10(8)11/h2,7-9H,1,3-6H2/t7-,8+,9+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072285
![PNG](/data/jpeg/tenK5007/BindingDB_50072285.png) ((3R,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072292
![PNG](/data/jpeg/tenK5007/BindingDB_50072292.png) ((3S,3aS,6aS)-3-Phenylsulfanyl-hexahydro-cyclopenta...)Show InChI InChI=1S/C13H14O2S/c14-13-12(10-7-4-8-11(10)15-13)16-9-5-2-1-3-6-9/h1-3,5-6,10-12H,4,7-8H2/t10-,11-,12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072289
![PNG](/data/jpeg/tenK5007/BindingDB_50072289.png) ((3S,3aR,6aS)-3-(4-Methyl-2-oxo-pent-3-enyl)-hexahy...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#6]-[#6@H]-1-[#6@H]-2-[#6]-[#6]-[#6]-[#6@@H]-2-[#8]-[#6]-1=O Show InChI InChI=1S/C13H18O3/c1-8(2)6-9(14)7-11-10-4-3-5-12(10)16-13(11)15/h6,10-12H,3-5,7H2,1-2H3/t10-,11+,12+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072283
![PNG](/data/jpeg/tenK5007/BindingDB_50072283.png) ((3S,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12+,13+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072286
![PNG](/data/jpeg/tenK5007/BindingDB_50072286.png) ((3R,3aR,6aS)-3-Benzyl-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C14H16O2/c15-14-12(9-10-5-2-1-3-6-10)11-7-4-8-13(11)16-14/h1-3,5-6,11-13H,4,7-9H2/t11-,12-,13+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072293
![PNG](/data/jpeg/tenK5007/BindingDB_50072293.png) (5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C12H20N2O2/c13-11(14)7-2-1-4-9-8-5-3-6-10(8)16-12(9)15/h8-10H,1-7H2,(H3,13,14)/t8-,9-,10+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072291
![PNG](/data/jpeg/tenK5007/BindingDB_50072291.png) (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1ccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)cc1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-6-4-9(5-7-10)8-12-11-2-1-3-13(11)19-15(12)18/h4-7,11-13H,1-3,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50072288
![PNG](/data/jpeg/tenK5007/BindingDB_50072288.png) (3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1cccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)c1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-4-1-3-9(7-10)8-12-11-5-2-6-13(11)19-15(12)18/h1,3-4,7,11-13H,2,5-6,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50072284
![PNG](/data/jpeg/tenK5007/BindingDB_50072284.png) ((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)Show SMILES [H][C@@]12[#6]-[#6][C@]3([#6])[C@@]4([H])[#6]-[#6][C@@]5([#6])[C@]6([H])[#6@@H](-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)-[#8][C@@]6([H])[#6][C@]5([#6])[#6]4=[#6]-[#6][C@@]3([H])[C@]1([#6])[#6](=O)-[#8]2 |r,c:33| Show InChI InChI=1S/C30H40O5/c1-16(2)13-17(31)14-18-24-21(34-25(18)32)15-29(5)20-7-8-22-27(3,19(20)9-12-28(24,29)4)11-10-23-30(22,6)26(33)35-23/h7,13,18-19,21-24H,8-12,14-15H2,1-6H3/t18-,19+,21+,22-,23-,24-,27-,28+,29-,30+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of human leukocyte elastase(HLE). |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072291
![PNG](/data/jpeg/tenK5007/BindingDB_50072291.png) (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1ccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)cc1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-6-4-9(5-7-10)8-12-11-2-1-3-13(11)19-15(12)18/h4-7,11-13H,1-3,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50072284
![PNG](/data/jpeg/tenK5007/BindingDB_50072284.png) ((1S,2R,4aR,6aS,6bS,7R,9aS,10aS)-2-Acetoxy-1,4a,6a,...)Show SMILES [H][C@@]12[#6]-[#6][C@]3([#6])[C@@]4([H])[#6]-[#6][C@@]5([#6])[C@]6([H])[#6@@H](-[#6]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)-[#8][C@@]6([H])[#6][C@]5([#6])[#6]4=[#6]-[#6][C@@]3([H])[C@]1([#6])[#6](=O)-[#8]2 |r,c:33| Show InChI InChI=1S/C30H40O5/c1-16(2)13-17(31)14-18-24-21(34-25(18)32)15-29(5)20-7-8-22-27(3,19(20)9-12-28(24,29)4)11-10-23-30(22,6)26(33)35-23/h7,13,18-19,21-24H,8-12,14-15H2,1-6H3/t18-,19+,21+,22-,23-,24-,27-,28+,29-,30+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072291
![PNG](/data/jpeg/tenK5007/BindingDB_50072291.png) (4-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1ccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)cc1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-6-4-9(5-7-10)8-12-11-2-1-3-13(11)19-15(12)18/h4-7,11-13H,1-3,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50072288
![PNG](/data/jpeg/tenK5007/BindingDB_50072288.png) (3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1cccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)c1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-4-1-3-9(7-10)8-12-11-5-2-6-13(11)19-15(12)18/h1,3-4,7,11-13H,2,5-6,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Inhibition of thrombin |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072293
![PNG](/data/jpeg/tenK5007/BindingDB_50072293.png) (5-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show InChI InChI=1S/C12H20N2O2/c13-11(14)7-2-1-4-9-8-5-3-6-10(8)16-12(9)15/h8-10H,1-7H2,(H3,13,14)/t8-,9-,10+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |
Chymotrypsin-C
(Homo sapiens (Human)) | BDBM50072288
![PNG](/data/jpeg/tenK5007/BindingDB_50072288.png) (3-((3R,3aR,6aS)-2-Oxo-hexahydro-cyclopenta[b]furan...)Show SMILES NC(=N)c1cccc(C[C@@H]2[C@H]3CCC[C@@H]3OC2=O)c1 Show InChI InChI=1S/C15H18N2O2/c16-14(17)10-4-1-3-9(7-10)8-12-11-5-2-6-13(11)19-15(12)18/h1,3-4,7,11-13H,2,5-6,8H2,(H3,16,17)/t11-,12-,13+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Research and Development
Curated by ChEMBL
| Assay Description Compound was evaluated for the inhibition of Chymotrypsinogen |
Bioorg Med Chem Lett 8: 2955-60 (1999)
Article DOI: 10.1016/S0960-894X(98)00531-9 BindingDB Entry DOI: 10.7270/Q2JQ105F |
More data for this Ligand-Target Pair | |