Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with all data for entry = 50010055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534783 (CHEMBL4575318) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C24H28N2O6Se2/c1-31-21(27)13-7-15-25-23(29)17-9-3-5-11-19(17)33-34-20-12-6-4-10-18(20)24(30)26-16-8-14-22(28)32-2/h3-6,9-12H,7-8,13-16H2,1-2H3,(H,25,29)(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	184	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	226	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50197347 (Ebselen Diselenide) Show SMILES O=C(Nc1ccccc1)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2Se2/c29-25(27-19-11-3-1-4-12-19)21-15-7-9-17-23(21)31-32-24-18-10-8-16-22(24)26(30)28-20-13-5-2-6-14-20/h1-18H,(H,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	651	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534782 (CHEMBL4471428) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C20H20N2O6Se2/c1-27-17(23)11-21-19(25)13-7-3-5-9-15(13)29-30-16-10-6-4-8-14(16)20(26)22-12-18(24)28-2/h3-10H,11-12H2,1-2H3,(H,21,25)(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	915	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534776 (CHEMBL4539240) Show SMILES [#6]-[#6]-[#6](-[#6]-[#8])-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6](-[#6]-[#6])-[#6]-[#8] Show InChI InChI=1S/C22H28N2O4Se2/c1-3-15(13-25)23-21(27)17-9-5-7-11-19(17)29-30-20-12-8-6-10-18(20)22(28)24-16(4-2)14-26/h5-12,15-16,25-26H,3-4,13-14H2,1-2H3,(H,23,27)(H,24,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50099857 (ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...) Show SMILES CC(=O)NO Show InChI InChI=1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 after 120 mins by Berthelot colorimetric analysis				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair				3D Structure (crystal)
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50070209 (Aciphex | CHEBI:8768 | LY-307640 | Rabeprazole) Show SMILES COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of Helicobacter pylori ATCC 43504 urease assessed as amount of ammonia after 15 mins by indophenol method				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM106944 (US8592468, EbSe2) Show SMILES O=c1[nH][se]c2ccccc12 Show InChI InChI=1S/C7H5NOSe/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534774 (CHEMBL4089739) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-n1[se;v2]c2ccccc2c1=O Show InChI InChI=1S/C10H9NO3Se/c1-14-9(12)6-11-10(13)7-4-2-3-5-8(7)15-11/h2-5H,6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534779 (CHEMBL4469463) Show SMILES [#6]-[#8]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-9(2)8-11(14(17)18-3)15-13(16)10-6-4-5-7-12(10)19-15/h4-7,9,11H,8H2,1-3H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534787 (CHEMBL4444060) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-9(2)8-11(14(17)18-3)15-13(16)10-6-4-5-7-12(10)19-15/h4-7,9,11H,8H2,1-3H3/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534774 (CHEMBL4089739) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-n1[se;v2]c2ccccc2c1=O Show InChI InChI=1S/C10H9NO3Se/c1-14-9(12)6-11-10(13)7-4-2-3-5-8(7)15-11/h2-5H,6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assay				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534778 (CHEMBL4563587) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C11H11NO3Se/c1-7(11(14)15-2)12-10(13)8-5-3-4-6-9(8)16-12/h3-7H,1-2H3/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534772 (CHEMBL4563580) Show SMILES [#6]-[#6]-[#6](-[#6])-[#6@@H](-[#6](=O)-[#8]-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-4-9(2)12(14(17)18-3)15-13(16)10-7-5-6-8-11(10)19-15/h5-9,12H,4H2,1-3H3/t9?,12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534780 (CHEMBL4469439) Show SMILES [#8]-[#6]-[#6@H](-c1ccccc1)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C15H13NO2Se/c17-10-13(11-6-2-1-3-7-11)16-15(18)12-8-4-5-9-14(12)19-16/h1-9,13,17H,10H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534773 (CHEMBL4524305) Show SMILES [#6]-[#6@H](-c1ccccc1)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C15H13NOSe/c1-11(12-7-3-2-4-8-12)16-15(17)13-9-5-6-10-14(13)18-16/h2-11H,1H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50197347 (Ebselen Diselenide) Show SMILES O=C(Nc1ccccc1)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2Se2/c29-25(27-19-11-3-1-4-12-19)21-15-7-9-17-23(21)31-32-24-18-10-8-16-22(24)26(30)28-20-13-5-2-6-14-20/h1-18H,(H,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM106944 (US8592468, EbSe2) Show SMILES O=c1[nH][se]c2ccccc12 Show InChI InChI=1S/C7H5NOSe/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534774 (CHEMBL4089739) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-n1[se;v2]c2ccccc2c1=O Show InChI InChI=1S/C10H9NO3Se/c1-14-9(12)6-11-10(13)7-4-2-3-5-8(7)15-11/h2-5H,6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50197347 (Ebselen Diselenide) Show SMILES O=C(Nc1ccccc1)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2Se2/c29-25(27-19-11-3-1-4-12-19)21-15-7-9-17-23(21)31-32-24-18-10-8-16-22(24)26(30)28-20-13-5-2-6-14-20/h1-18H,(H,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534783 (CHEMBL4575318) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C24H28N2O6Se2/c1-31-21(27)13-7-15-25-23(29)17-9-3-5-11-19(17)33-34-20-12-6-4-10-18(20)24(30)26-16-8-14-22(28)32-2/h3-6,9-12H,7-8,13-16H2,1-2H3,(H,25,29)(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534778 (CHEMBL4563587) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C11H11NO3Se/c1-7(11(14)15-2)12-10(13)8-5-3-4-6-9(8)16-12/h3-7H,1-2H3/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534783 (CHEMBL4575318) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C24H28N2O6Se2/c1-31-21(27)13-7-15-25-23(29)17-9-3-5-11-19(17)33-34-20-12-6-4-10-18(20)24(30)26-16-8-14-22(28)32-2/h3-6,9-12H,7-8,13-16H2,1-2H3,(H,25,29)(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534780 (CHEMBL4469439) Show SMILES [#8]-[#6]-[#6@H](-c1ccccc1)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C15H13NO2Se/c17-10-13(11-6-2-1-3-7-11)16-15(18)12-8-4-5-9-14(12)19-16/h1-9,13,17H,10H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534773 (CHEMBL4524305) Show SMILES [#6]-[#6@H](-c1ccccc1)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C15H13NOSe/c1-11(12-7-3-2-4-8-12)16-15(17)13-9-5-6-10-14(13)18-16/h2-11H,1H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534777 (CHEMBL4592440) Show SMILES [#6]-[#6](-[#6])-[#6@@H](-[#6](-[#8])=O)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C12H13NO3Se/c1-7(2)10(12(15)16)13-11(14)8-5-3-4-6-9(8)17-13/h3-7,10H,1-2H3,(H,15,16)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534772 (CHEMBL4563580) Show SMILES [#6]-[#6]-[#6](-[#6])-[#6@@H](-[#6](=O)-[#8]-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-4-9(2)12(14(17)18-3)15-13(16)10-7-5-6-8-11(10)19-15/h5-9,12H,4H2,1-3H3/t9?,12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534786 (CHEMBL3747132) Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](-[#8])=O)-[#6](-[#8])=O |r| Show InChI InChI=1S/C20H20N2O6Se2/c1-11(19(25)26)21-17(23)13-7-3-5-9-15(13)29-30-16-10-6-4-8-14(16)18(24)22-12(2)20(27)28/h3-12H,1-2H3,(H,21,23)(H,22,24)(H,25,26)(H,27,28)/t11-,12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534787 (CHEMBL4444060) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-9(2)8-11(14(17)18-3)15-13(16)10-6-4-5-7-12(10)19-15/h4-7,9,11H,8H2,1-3H3/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534771 (CHEMBL4461450) Show SMILES [#8]-[#6](=O)-[#6]-[#6]-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6](-[#8])=O Show InChI InChI=1S/C22H24N2O6Se2/c25-19(26)11-5-13-23-21(29)15-7-1-3-9-17(15)31-32-18-10-4-2-8-16(18)22(30)24-14-6-12-20(27)28/h1-4,7-10H,5-6,11-14H2,(H,23,29)(H,24,30)(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534785 (CHEMBL4444989) Show SMILES [#8]-[#6](=O)-[#6]-[#6]-[#6]-n1[se;v2]c2ccccc2c1=O Show InChI InChI=1S/C11H11NO3Se/c13-10(14)6-3-7-12-11(15)8-4-1-2-5-9(8)16-12/h1-2,4-5H,3,6-7H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534770 (CHEMBL4552531 | acs.jmedchem.1c00409_ST.158) Show SMILES [#8]-[#6](=O)-[#6]-[#6]-n1[se;v2]c2ccccc2c1=O Show InChI InChI=1S/C10H9NO3Se/c12-9(13)5-6-11-10(14)7-3-1-2-4-8(7)15-11/h1-4H,5-6H2,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534777 (CHEMBL4592440) Show SMILES [#6]-[#6](-[#6])-[#6@@H](-[#6](-[#8])=O)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C12H13NO3Se/c1-7(2)10(12(15)16)13-11(14)8-5-3-4-6-9(8)17-13/h3-7,10H,1-2H3,(H,15,16)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50197347 (Ebselen Diselenide) Show SMILES O=C(Nc1ccccc1)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2Se2/c29-25(27-19-11-3-1-4-12-19)21-15-7-9-17-23(21)31-32-24-18-10-8-16-22(24)26(30)28-20-13-5-2-6-14-20/h1-18H,(H,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assay				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534779 (CHEMBL4469463) Show SMILES [#6]-[#8]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-9(2)8-11(14(17)18-3)15-13(16)10-6-4-5-7-12(10)19-15/h4-7,9,11H,8H2,1-3H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assay				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM106944 (US8592468, EbSe2) Show SMILES O=c1[nH][se]c2ccccc12 Show InChI InChI=1S/C7H5NOSe/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534784 (CHEMBL4520558) Show SMILES [#8]-[#6](=O)-[#6]-[#6@@H](-[#6](-[#8])=O)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C11H9NO5Se/c13-9(14)5-7(11(16)17)12-10(15)6-3-1-2-4-8(6)18-12/h1-4,7H,5H2,(H,13,14)(H,16,17)/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM34233 (2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...) Show SMILES O=c1n([se]c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534781 (CHEMBL4463967) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@@H](-[#6](-[#8])=O)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C13H15NO3Se/c1-8(2)7-10(13(16)17)14-12(15)9-5-3-4-6-11(9)18-14/h3-6,8,10H,7H2,1-2H3,(H,16,17)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534778 (CHEMBL4563587) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C11H11NO3Se/c1-7(11(14)15-2)12-10(13)8-5-3-4-6-9(8)16-12/h3-7H,1-2H3/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534778 (CHEMBL4563587) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C11H11NO3Se/c1-7(11(14)15-2)12-10(13)8-5-3-4-6-9(8)16-12/h3-7H,1-2H3/t7-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assay				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534779 (CHEMBL4469463) Show SMILES [#6]-[#8]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C14H17NO3Se/c1-9(2)8-11(14(17)18-3)15-13(16)10-6-4-5-7-12(10)19-15/h4-7,9,11H,8H2,1-3H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate after 2 hrs by Berthelot assay				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534780 (CHEMBL4469439) Show SMILES [#8]-[#6]-[#6@H](-c1ccccc1)-n1[se;v2]c2ccccc2c1=O |r| Show InChI InChI=1S/C15H13NO2Se/c17-10-13(11-6-2-1-3-7-11)16-15(18)12-8-4-5-9-14(12)19-16/h1-9,13,17H,10H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534782 (CHEMBL4471428) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C20H20N2O6Se2/c1-27-17(23)11-21-19(25)13-7-3-5-9-15(13)29-30-16-10-6-4-8-14(16)20(26)22-12-18(24)28-2/h3-10H,11-12H2,1-2H3,(H,21,25)(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of urease in Helicobacter pylori J99 in Brucella broth using urea as substrate preincubated for 2 hrs followed by substrate addition measu...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534786 (CHEMBL3747132) Show SMILES [#6]-[#6@H](-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](-[#8])=O)-[#6](-[#8])=O |r| Show InChI InChI=1S/C20H20N2O6Se2/c1-11(19(25)26)21-17(23)13-7-3-5-9-15(13)29-30-16-10-6-4-8-14(16)18(24)22-12(2)20(27)28/h3-12H,1-2H3,(H,21,23)(H,22,24)(H,25,26)(H,27,28)/t11-,12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50534782 (CHEMBL4471428) Show SMILES [#6]-[#8]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccccc1[Se;v2][Se;v2]c1ccccc1-[#6](=O)-[#7]-[#6]-[#6](=O)-[#8]-[#6] Show InChI InChI=1S/C20H20N2O6Se2/c1-27-17(23)11-21-19(25)13-7-3-5-9-15(13)29-30-16-10-6-4-8-14(16)20(26)22-12-18(24)28-2/h3-10H,11-12H2,1-2H3,(H,21,25)(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50197347 (Ebselen Diselenide) Show SMILES O=C(Nc1ccccc1)c1ccccc1[Se][Se]c1ccccc1C(=O)Nc1ccccc1 Show InChI InChI=1S/C26H20N2O2Se2/c29-25(27-19-11-3-1-4-12-19)21-15-7-9-17-23(21)31-32-24-18-10-8-16-22(24)26(30)28-20-13-5-2-6-14-20/h1-18H,(H,27,29)(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wroc?aw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant Helicobacter pylori urease expressed in Escherichia coli rosetta DE3 using urea as substrate assessed as transformed cell u...				J Med Chem 59: 8125-33 (2016) Article DOI: 10.1021/acs.jmedchem.6b00986 BindingDB Entry DOI: 10.7270/Q2FR0130
					More data for this Ligand-Target Pair

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