Compile Data Set for Download or QSAR

Found 128 hits Enz. Inhib. hit(s) with all data for entry = 50010256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536857 (CHEMBL4581663) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2c(F)cccc12 |r| Show InChI InChI=1S/C23H20F2N2O3/c24-13-16(28)14-26-23(30)21(12-15-6-2-1-3-7-15)27-22(29)19-10-4-9-18-17(19)8-5-11-20(18)25/h1-11,21H,12-14H2,(H,26,30)(H,27,29)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536857 (CHEMBL4581663) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2c(F)cccc12 |r| Show InChI InChI=1S/C23H20F2N2O3/c24-13-16(28)14-26-23(30)21(12-15-6-2-1-3-7-15)27-22(29)19-10-4-9-18-17(19)8-5-11-20(18)25/h1-11,21H,12-14H2,(H,26,30)(H,27,29)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536833 (CHEMBL4546760) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(F)c2ccccc12 |r| Show InChI InChI=1S/C23H20F2N2O3/c24-13-16(28)14-26-23(30)21(12-15-6-2-1-3-7-15)27-22(29)19-10-11-20(25)18-9-5-4-8-17(18)19/h1-11,21H,12-14H2,(H,26,30)(H,27,29)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536838 (CHEMBL4520267) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-18(27)15-25-23(29)21(13-16-7-2-1-3-8-16)26-22(28)20-12-6-10-17-9-4-5-11-19(17)20/h1-12,21H,13-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536838 (CHEMBL4520267) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-18(27)15-25-23(29)21(13-16-7-2-1-3-8-16)26-22(28)20-12-6-10-17-9-4-5-11-19(17)20/h1-12,21H,13-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Calpain-1/Calpain-2 catalytic subunit (Homo sapiens (Human))	BDBM50536838 (CHEMBL4520267) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-18(27)15-25-23(29)21(13-16-7-2-1-3-8-16)26-22(28)20-12-6-10-17-9-4-5-11-19(17)20/h1-12,21H,13-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of calpain (unknown origin) using calpain substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader a...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536833 (CHEMBL4546760) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(F)c2ccccc12 |r| Show InChI InChI=1S/C23H20F2N2O3/c24-13-16(28)14-26-23(30)21(12-15-6-2-1-3-7-15)27-22(29)19-10-11-20(25)18-9-5-4-8-17(18)19/h1-11,21H,12-14H2,(H,26,30)(H,27,29)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536856 (CHEMBL4520585) Show SMILES CN(CC(=O)CF)C(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H23FN2O3/c1-27(16-19(28)15-25)24(30)22(14-17-8-3-2-4-9-17)26-23(29)21-13-7-11-18-10-5-6-12-20(18)21/h2-13,22H,14-16H2,1H3,(H,26,29)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536844 (CHEMBL4553669) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnnc2ccccc12 |r| Show InChI InChI=1S/C21H19FN4O3/c22-11-15(27)12-23-21(29)19(10-14-6-2-1-3-7-14)25-20(28)17-13-24-26-18-9-5-4-8-16(17)18/h1-9,13,19H,10-12H2,(H,23,29)(H,25,28)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50536838 (CHEMBL4520267) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-18(27)15-25-23(29)21(13-16-7-2-1-3-8-16)26-22(28)20-12-6-10-17-9-4-5-11-19(17)20/h1-12,21H,13-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin B (332 residues) expressed in CHO cells using Z-FR-AMC as substrate preincubated for 20 mins followed by su...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536856 (CHEMBL4520585) Show SMILES CN(CC(=O)CF)C(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H23FN2O3/c1-27(16-19(28)15-25)24(30)22(14-17-8-3-2-4-9-17)26-23(29)21-13-7-11-18-10-5-6-12-20(18)21/h2-13,22H,14-16H2,1H3,(H,26,29)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536844 (CHEMBL4553669) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnnc2ccccc12 |r| Show InChI InChI=1S/C21H19FN4O3/c22-11-15(27)12-23-21(29)19(10-14-6-2-1-3-7-14)25-20(28)17-13-24-26-18-9-5-4-8-16(17)18/h1-9,13,19H,10-12H2,(H,23,29)(H,25,28)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536845 (CHEMBL4567870) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C22H20FN3O3/c23-13-16(27)14-25-22(29)20(12-15-6-2-1-3-7-15)26-21(28)18-10-11-24-19-9-5-4-8-17(18)19/h1-11,20H,12-14H2,(H,25,29)(H,26,28)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50536839 (CHEMBL2402203 | acs.jmedchem.1c00409_ST.724) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)CF |r| Show InChI InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin B (332 residues) expressed in CHO cells using Z-FR-AMC as substrate preincubated for 20 mins followed by su...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536845 (CHEMBL4567870) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccnc2ccccc12 |r| Show InChI InChI=1S/C22H20FN3O3/c23-13-16(27)14-25-22(29)20(12-15-6-2-1-3-7-15)26-21(28)18-10-11-24-19-9-5-4-8-17(18)19/h1-11,20H,12-14H2,(H,25,29)(H,26,28)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Calpain-1/Calpain-2 catalytic subunit (Homo sapiens (Human))	BDBM50536834 (CHEMBL4590201) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19FN2O3/c20-12-16(23)13-21-19(25)17(11-14-7-3-1-4-8-14)22-18(24)15-9-5-2-6-10-15/h1-10,17H,11-13H2,(H,21,25)(H,22,24)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of calpain (unknown origin) using calpain substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader a...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Calpain-1/Calpain-2 catalytic subunit (Homo sapiens (Human))	BDBM50536839 (CHEMBL2402203 | acs.jmedchem.1c00409_ST.724) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)CF |r| Show InChI InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of calpain (unknown origin) using calpain substrate preincubated for 20 mins followed by substrate addition by fluorescence plate reader a...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50536834 (CHEMBL4590201) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19FN2O3/c20-12-16(23)13-21-19(25)17(11-14-7-3-1-4-8-14)22-18(24)15-9-5-2-6-10-15/h1-10,17H,11-13H2,(H,21,25)(H,22,24)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of recombinant human cathepsin B (332 residues) expressed in CHO cells using Z-FR-AMC as substrate preincubated for 20 mins followed by su...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536858 (CHEMBL4578571) Show SMILES COc1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)CF |r| Show InChI InChI=1S/C20H21FN2O4/c1-27-17-9-5-8-15(11-17)19(25)23-18(10-14-6-3-2-4-7-14)20(26)22-13-16(24)12-21/h2-9,11,18H,10,12-13H2,1H3,(H,22,26)(H,23,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536849 (CHEMBL4574173) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O3/c21-13-17(24)14-22-20(26)18(11-15-7-3-1-4-8-15)23-19(25)12-16-9-5-2-6-10-16/h1-10,18H,11-14H2,(H,22,26)(H,23,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536836 (CHEMBL4579064) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI InChI=1S/C17H17FN4O3/c18-9-13(23)10-21-16(24)14(8-12-4-2-1-3-5-12)22-17(25)15-11-19-6-7-20-15/h1-7,11,14H,8-10H2,(H,21,24)(H,22,25)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536836 (CHEMBL4579064) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1 |r| Show InChI InChI=1S/C17H17FN4O3/c18-9-13(23)10-21-16(24)14(8-12-4-2-1-3-5-12)22-17(25)15-11-19-6-7-20-15/h1-7,11,14H,8-10H2,(H,21,24)(H,22,25)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536862 (CHEMBL4588146) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H18ClFN2O3/c20-15-8-4-7-14(10-15)18(25)23-17(9-13-5-2-1-3-6-13)19(26)22-12-16(24)11-21/h1-8,10,17H,9,11-12H2,(H,22,26)(H,23,25)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536847 (CHEMBL4535723) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H18F4N2O3/c21-11-16(27)12-25-19(29)17(9-13-5-2-1-3-6-13)26-18(28)14-7-4-8-15(10-14)20(22,23)24/h1-8,10,17H,9,11-12H2,(H,25,29)(H,26,28)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536846 (CHEMBL4567655) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-20(27)15-25-23(29)21(12-16-6-2-1-3-7-16)26-22(28)19-11-10-17-8-4-5-9-18(17)13-19/h1-11,13,21H,12,14-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536851 (CHEMBL4539211) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H20ClFN2O4/c21-16-8-4-7-15(9-16)10-18(19(26)23-12-17(25)11-22)24-20(27)28-13-14-5-2-1-3-6-14/h1-9,18H,10-13H2,(H,23,26)(H,24,27)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536837 (CHEMBL4572200) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O4/c21-12-17(24)13-22-19(25)18(11-15-7-3-1-4-8-15)23-20(26)27-14-16-9-5-2-6-10-16/h1-10,18H,11-14H2,(H,22,25)(H,23,26)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536846 (CHEMBL4567655) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C23H21FN2O3/c24-14-20(27)15-25-23(29)21(12-16-6-2-1-3-7-16)26-22(28)19-11-10-17-8-4-5-9-18(17)13-19/h1-11,13,21H,12,14-15H2,(H,25,29)(H,26,28)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536837 (CHEMBL4572200) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O4/c21-12-17(24)13-22-19(25)18(11-15-7-3-1-4-8-15)23-20(26)27-14-16-9-5-2-6-10-16/h1-10,18H,11-14H2,(H,22,25)(H,23,26)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of full length N-terminal His6-tagged ATG4B (unknown origin) expressed in Escherichia coli BL21(DE3) cells using His-GATE-16-GST as substr...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536834 (CHEMBL4590201) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19FN2O3/c20-12-16(23)13-21-19(25)17(11-14-7-3-1-4-8-14)22-18(24)15-9-5-2-6-10-15/h1-10,17H,11-13H2,(H,21,25)(H,22,24)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536862 (CHEMBL4588146) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H18ClFN2O3/c20-15-8-4-7-14(10-15)18(25)23-17(9-13-5-2-1-3-6-13)19(26)22-12-16(24)11-21/h1-8,10,17H,9,11-12H2,(H,22,26)(H,23,25)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536837 (CHEMBL4572200) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O4/c21-12-17(24)13-22-19(25)18(11-15-7-3-1-4-8-15)23-20(26)27-14-16-9-5-2-6-10-16/h1-10,18H,11-14H2,(H,22,25)(H,23,26)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536847 (CHEMBL4535723) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H18F4N2O3/c21-11-16(27)12-25-19(29)17(9-13-5-2-1-3-6-13)26-18(28)14-7-4-8-15(10-14)20(22,23)24/h1-8,10,17H,9,11-12H2,(H,25,29)(H,26,28)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536851 (CHEMBL4539211) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1cccc(Cl)c1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H20ClFN2O4/c21-16-8-4-7-15(9-16)10-18(19(26)23-12-17(25)11-22)24-20(27)28-13-14-5-2-1-3-6-14/h1-9,18H,10-13H2,(H,23,26)(H,24,27)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536848 (CHEMBL4569375) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCCC1 |r| Show InChI InChI=1S/C18H23FN2O3/c19-11-15(22)12-20-18(24)16(10-13-6-2-1-3-7-13)21-17(23)14-8-4-5-9-14/h1-3,6-7,14,16H,4-5,8-12H2,(H,20,24)(H,21,23)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536832 (CHEMBL4562540) Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)CF |r| Show InChI InChI=1S/C17H23FN2O4/c1-17(2,3)24-16(23)20-14(9-12-7-5-4-6-8-12)15(22)19-11-13(21)10-18/h4-8,14H,9-11H2,1-3H3,(H,19,22)(H,20,23)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536834 (CHEMBL4590201) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1 |r| Show InChI InChI=1S/C19H19FN2O3/c20-12-16(23)13-21-19(25)17(11-14-7-3-1-4-8-14)22-18(24)15-9-5-2-6-10-15/h1-10,17H,11-13H2,(H,21,25)(H,22,24)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536858 (CHEMBL4578571) Show SMILES COc1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)CF |r| Show InChI InChI=1S/C20H21FN2O4/c1-27-17-9-5-8-15(11-17)19(25)23-18(10-14-6-3-2-4-7-14)20(26)22-13-16(24)12-21/h2-9,11,18H,10,12-13H2,1H3,(H,22,26)(H,23,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536867 (CHEMBL4554009) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccnn1 |r| Show InChI InChI=1S/C17H17FN4O3/c18-10-13(23)11-19-16(24)15(9-12-5-2-1-3-6-12)21-17(25)14-7-4-8-20-22-14/h1-8,15H,9-11H2,(H,19,24)(H,21,25)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536849 (CHEMBL4574173) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O3/c21-13-17(24)14-22-20(26)18(11-15-7-3-1-4-8-15)23-19(25)12-16-9-5-2-6-10-16/h1-10,18H,11-14H2,(H,22,26)(H,23,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536848 (CHEMBL4569375) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCCC1 |r| Show InChI InChI=1S/C18H23FN2O3/c19-11-15(22)12-20-18(24)16(10-13-6-2-1-3-7-13)21-17(23)14-8-4-5-9-14/h1-3,6-7,14,16H,4-5,8-12H2,(H,20,24)(H,21,23)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536850 (CHEMBL4570064) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1cccc(F)c1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H20F2N2O4/c21-11-17(25)12-23-19(26)18(10-15-7-4-8-16(22)9-15)24-20(27)28-13-14-5-2-1-3-6-14/h1-9,18H,10-13H2,(H,23,26)(H,24,27)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536832 (CHEMBL4562540) Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)CF |r| Show InChI InChI=1S/C17H23FN2O4/c1-17(2,3)24-16(23)20-14(9-12-7-5-4-6-8-12)15(22)19-11-13(21)10-18/h4-8,14H,9-11H2,1-3H3,(H,19,22)(H,20,23)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536843 (CHEMBL4566679) Show SMILES COc1ccc2ccccc2c1C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)CF |r| Show InChI InChI=1S/C24H23FN2O4/c1-31-21-12-11-17-9-5-6-10-19(17)22(21)24(30)27-20(13-16-7-3-2-4-8-16)23(29)26-15-18(28)14-25/h2-12,20H,13-15H2,1H3,(H,26,29)(H,27,30)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536839 (CHEMBL2402203 | acs.jmedchem.1c00409_ST.724) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)CF |r| Show InChI InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536850 (CHEMBL4570064) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1cccc(F)c1)NC(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C20H20F2N2O4/c21-11-17(25)12-23-19(26)18(10-15-7-4-8-16(22)9-15)24-20(27)28-13-14-5-2-1-3-6-14/h1-9,18H,10-13H2,(H,23,26)(H,24,27)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536866 (CHEMBL4525169) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2cccnc12 |r| Show InChI InChI=1S/C22H20FN3O3/c23-13-17(27)14-25-22(29)19(12-15-6-2-1-3-7-15)26-21(28)18-10-4-8-16-9-5-11-24-20(16)18/h1-11,19H,12-14H2,(H,25,29)(H,26,28)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536860 (CHEMBL4527514) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)COc1ccccc1 |r| Show InChI InChI=1S/C20H21FN2O4/c21-12-16(24)13-22-20(26)18(11-15-7-3-1-4-8-15)23-19(25)14-27-17-9-5-2-6-10-17/h1-10,18H,11-14H2,(H,22,26)(H,23,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536859 (CHEMBL4540188) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccccc1 |r| Show InChI InChI=1S/C21H23FN2O3/c22-14-18(25)15-23-21(27)19(13-17-9-5-2-6-10-17)24-20(26)12-11-16-7-3-1-4-8-16/h1-10,19H,11-15H2,(H,23,27)(H,24,26)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) using His-GATE-16-GST as substrate preincubated for 30 mins followed by substrate addition measured after 30 min...				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair
Cysteine protease ATG4B (Homo sapiens (Human))	BDBM50536866 (CHEMBL4525169) Show SMILES FCC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)c1cccc2cccnc12 |r| Show InChI InChI=1S/C22H20FN3O3/c23-13-17(27)14-25-22(29)19(12-15-6-2-1-3-7-15)26-21(28)18-10-4-8-16-9-5-11-24-20(16)18/h1-11,19H,12-14H2,(H,25,29)(H,26,28)/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development Curated by ChEMBL					Assay Description Inhibition of ATG4B (unknown origin) expressed in HEK293T cells coexpressing HTRA4 and Actin-LC3B-dNGLuc after 24 hrs by luciferase release assay				ACS Med Chem Lett 7: 802-6 (2016) Article DOI: 10.1021/acsmedchemlett.6b00208 BindingDB Entry DOI: 10.7270/Q2QF8XCR
					More data for this Ligand-Target Pair

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