BindingDB PrimarySearch

Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50013431
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50565800 (Azd-1390 \| Azd1390) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ATM (unknown origin) assessed as ATM-dependent phosphorylation using GST-p53 ser15 as substrate				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Wee1-like protein kinase (Homo sapiens (Human))	BDBM50565801 (CHEMBL4780868) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of kinase tracer178 from recombinant WEE1 (unknown origin) incubated for 1 hr by lanthascreen TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50110178 (CHEMBL3603847 \| US10787436, Compound I-23) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CDK7 incubated for 180 mins by LanthaScreen Eu Kinase binding assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Wee1-like protein kinase (Homo sapiens (Human))	BDBM50240826 (AZD-1775 \| MK-1775 \| US11124518, Example AZD1775 \|...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal GST-fused human WEE1 (215 to 646 residues) expressed in baculovirus expression system using poly(Lys,Tyr) as substrate incub...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50565799 (CHEMBL4780892) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ATM (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
ATR-interacting protein/Serine/threonine-protein kinase ATR (Homo sapiens (Human))	BDBM268079 (2-[(3R)-3-methylmorpholin-4-yl]-4-(1-methyl-1H-pyr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of 5-TAMRA-labelled Tracer A from human GST-fused/FLAG-tagged full length ATR/human N-terminal FLAG-tagged full length ATRIP expressed i...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50145038 (CHEMBL2143829) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length Flag-tagged ATM (unknown origin) using GST-p53(1 to 101 residues) as substrates incubated for 90 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50208517 (2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one \| C...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HeLa nuclear extract derived ATM using glutathioneS-transferase-p53N66 as substrate preincubated for 10 mins followed by ATP addi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Wee1-like protein kinase (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full length WEE1 (unknown origin) assessed as reduction in cdc2/cyclin B phosphorylation using biotinylated histone H1 peptide (PKTPKKA...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM50139171 (Dinaciclib \| MK-7965 \| SCH-727965 \| US11643396, Ex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CDK12 (696 to 1082 residues)/human cyclinK (1 to 267 residues) using pol2 CTD-peptide substrate and [gammaP]ATP by scintillation ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 13/Cyclin-K (Homo sapiens (Human))	BDBM50528813 (CHEMBL4163879) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK13/human cyclin K expressed in baculovirus-infected insect cells using pol2 CTD-peptide substrate and [gammaP]ATP by scintillation c...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM413450 (7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PDB UniChem	PDB Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DNA-PK in human A549 cells assessed as reduction in radiation-induced autophosphorylation at S2056 residue preincubated for 1 hr follow...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-SRC (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EGFR (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR1 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MYT1 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFR-beta (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM3096 (2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. \| 6...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK1 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM50528813 (CHEMBL4163879) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CDK12/human cyclin K expressed in baculovirus-infected insect cells using pol2 CTD-peptide substrate and [gammaP]ATP by scintilla...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 13 (Homo sapiens (Human))	BDBM50110178 (CHEMBL3603847 \| US10787436, Compound I-23) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK13 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50070942 ((-)-Epigallocatechin gallate \| (-)-Epigallocatechi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one \|...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI3K alpha (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one \|...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI3K delta (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Cyclin-dependent kinase 12 (Homo sapiens)	BDBM50110178 (CHEMBL3603847 \| US10787436, Compound I-23) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	864	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CDK12 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one \|...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PI3K beta (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50436204 (CHEMBL109037) Show SMILES NC(Cc1cc(O)c(O)cc1O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565810 (Strictinin) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50187665 ((-)-epigallocatechin \| CHEMBL47386) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Serine-protein kinase ATM (Homo sapiens (Human))	BDBM50565798 (CHEMBL4789596) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human HeLa nuclear extract derived ATM using glutathioneS-transferase-p53N66 as substrate preincubated for 10 mins followed by ATP addi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565806 (CHEMBL4795092) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565807 (CHEMBL4785174) Show SMILES Oc1ccc(cc1N=Cc1ccc[nH]1)N=Cc1ccc[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565808 (CHEMBL4785369) Show SMILES OC(=O)c1ccc(\C=N\c2nc[nH]n2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM23223 (7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565809 (CHEMBL1718911) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human RAD52 assessed as reduction in DNA annealing using tailed ds-DNA 337-F/1337-BHQ1 by fluorescence-quenching assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565805 (CHEMBL4785153) Show SMILES CC(C)Oc1c(-c2ccco2)c(=O)c1=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565804 (CHEMBL4796552) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565803 (CHEMBL4777728) Show SMILES Cn1cccc1C=CC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM60996 (5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD52 homolog (Homo sapiens)	BDBM50565802 (CHEMBL4165444 \| US11584714, Compound 29) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50565800 (Azd-1390 \| Azd1390) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM48804 (3-(phenylmethyl)-2-[(E)-2-(3-pyridinyl)ethenyl]-4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human RAD51 using 90-mer ssDNA as substrate measured after 30 mins by D-loop assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM245474 (US9428503, 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERG				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00766 BindingDB Entry DOI: 10.7270/Q2GX4G9M
TBA					More data for this Ligand-Target Pair