Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50015293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) at 1 uM by kinomescan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585053 (CHEMBL5089965) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3n2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585047 (CHEMBL5075335) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCC1=O)c4)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585053 (CHEMBL5089965) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3n2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585047 (CHEMBL5075335) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCC1=O)c4)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) at 1 uM by kinomescan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-6 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK4 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585049 (CHEMBL5075321) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(C)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585049 (CHEMBL5075321) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(C)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK3 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585047 (CHEMBL5075335) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCC1=O)c4)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK2 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK1 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585050 (CHEMBL5081601) Show SMILES COc1c-2c(CN(C(C)C)C(=O)CCCn3cc(-c4c[nH]c5ncc-2cc45)c(n3)C(F)(F)F)nn1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TNIK (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Misshapen-like kinase 1 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MINK1 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 4 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MEK4 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585050 (CHEMBL5081601) Show SMILES COc1c-2c(CN(C(C)C)C(=O)CCCn3cc(-c4c[nH]c5ncc-2cc45)c(n3)C(F)(F)F)nn1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585048 (CHEMBL5079894) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCCC1=O)c4)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585047 (CHEMBL5075335) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCC1=O)c4)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 4 (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MEK4 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of RSK2 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585048 (CHEMBL5079894) Show SMILES CN1Cc2nn(C)cc2-c2cnc3[nH]cc(-c4cnn(CCCCC1=O)c4)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAK (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SGK (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585051 (CHEMBL5086482) Show SMILES COc1c-2c(CN(C(C)C)C(=O)CCCn3cc(c(n3)C(F)(F)F)-c3c(C)[nH]c4ncc-2cc34)nn1C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50391956 (CHEMBL2152265) Show SMILES Nc1cccc(c1)-c1cnc2[nH]cc(-c3cccnc3)c2c1 Show InChI InChI=1S/C18H14N4/c19-15-5-1-3-12(7-15)14-8-16-17(11-22-18(16)21-10-14)13-4-2-6-20-9-13/h1-11H,19H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MYLK (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	354	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLT3 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	477	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585051 (CHEMBL5086482) Show SMILES COc1c-2c(CN(C(C)C)C(=O)CCCn3cc(c(n3)C(F)(F)F)-c3c(C)[nH]c4ncc-2cc34)nn1C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585052 (CHEMBL5089643) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]nc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of SGK (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type 1B (Homo sapiens (Human))	BDBM50585045 (CHEMBL5093741) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]cc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CAMK1B (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585052 (CHEMBL5089643) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]nc(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	929	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JNK2 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JNK1 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 19 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of YSK4 (unknown origin) at 1 uM by kinome scan method				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50585054 (CHEMBL5088208) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cc3c(c[nH]c3nn2)-c2cn(CCCC1=O)nc2C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1B (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50585054 (CHEMBL5088208) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cc3c(c[nH]c3nn2)-c2cn(CCCC1=O)nc2C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50585046 (CHEMBL5086263) Show SMILES CN1Cc2nn(C)c(C#N)c2-c2cnc3[nH]c(F)c(-c4cn(CCCC1=O)nc4C(F)(F)F)c3c2 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JNK3 (unknown origin) in human CAL-27 cells measured after 6 hrs by select screen kinase assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00630 BindingDB Entry DOI: 10.7270/Q2183BDB
					More data for this Ligand-Target Pair