Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50018183 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405860
(CHEMBL5278170)Show SMILES CC(C)(C)C(=O)Nc1c(OC(=O)C(C)(C)C)ccc2nc(sc12)S(N)(=O)=O Show InChI InChI=1S/C17H23N3O5S2/c1-16(2,3)13(21)20-11-10(25-14(22)17(4,5)6)8-7-9-12(11)26-15(19-9)27(18,23)24/h7-8H,1-6H3,(H,20,21)(H2,18,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405864
(CHEMBL5285314)Show InChI InChI=1S/C12H15N3O4S2/c1-12(2,3)10(16)19-7-5-4-6-9(8(7)13)20-11(15-6)21(14,17)18/h4-5H,13H2,1-3H3,(H2,14,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405855
(CHEMBL5267293)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,3)19-11(15)18-7-4-5-8-9(6-7)20-10(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405859
(CHEMBL5271818)Show InChI InChI=1S/C15H20N2O4S2/c1-2-3-4-5-6-7-14(18)21-11-8-9-12-13(10-11)22-15(17-12)23(16,19)20/h8-10H,2-7H2,1H3,(H2,16,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405863
(CHEMBL5284821)Show InChI InChI=1S/C9H8N2O4S2/c1-5(12)15-6-2-3-7-8(4-6)16-9(11-7)17(10,13)14/h2-4H,1H3,(H2,10,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405869
(CHEMBL5289588)Show SMILES NS(=O)(=O)c1nc2ccc(OC(=O)\C=C\c3ccccc3)cc2s1 Show InChI InChI=1S/C16H12N2O4S2/c17-24(20,21)16-18-13-8-7-12(10-14(13)23-16)22-15(19)9-6-11-4-2-1-3-5-11/h1-10H,(H2,17,20,21)/b9-6+ | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405868
(CHEMBL5285121)Show SMILES NS(=O)(=O)c1nc2ccc(OC(=O)Cc3ccc(Cl)cc3)cc2s1 Show InChI InChI=1S/C15H11ClN2O4S2/c16-10-3-1-9(2-4-10)7-14(19)22-11-5-6-12-13(8-11)23-15(18-12)24(17,20)21/h1-6,8H,7H2,(H2,17,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405867
(CHEMBL5283527)Show InChI InChI=1S/C13H16N2O5S2/c1-4-19-13(2,3)11(16)20-8-5-6-9-10(7-8)21-12(15-9)22(14,17)18/h5-7H,4H2,1-3H3,(H2,14,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405854
(CHEMBL5282587)Show InChI InChI=1S/C10H11N3O4S2/c1-13(2)10(14)17-6-3-4-7-8(5-6)18-9(12-7)19(11,15)16/h3-5H,1-2H3,(H2,11,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405853
(CHEMBL5273189)Show InChI InChI=1S/C12H14N2O5S2/c1-7(2)6-18-12(15)19-8-3-4-9-10(5-8)20-11(14-9)21(13,16)17/h3-5,7H,6H2,1-2H3,(H2,13,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405851
(CHEMBL5283686)Show SMILES COc1cccc(OC)c1C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C16H14N2O6S2/c1-22-11-4-3-5-12(23-2)14(11)15(19)24-9-6-7-10-13(8-9)25-16(18-10)26(17,20)21/h3-8H,1-2H3,(H2,17,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405850
(CHEMBL5273001)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,18-3)10(15)19-7-4-5-8-9(6-7)20-11(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405866
(CHEMBL5267725)Show SMILES CCOCCOCCOC(C)(C)C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C17H24N2O7S2/c1-4-23-7-8-24-9-10-25-17(2,3)15(20)26-12-5-6-13-14(11-12)27-16(19-13)28(18,21)22/h5-6,11H,4,7-10H2,1-3H3,(H2,18,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405865
(CHEMBL5286922)Show InChI InChI=1S/C12H14N2O4S2/c1-12(2,3)10(15)18-7-4-5-8-9(6-7)19-11(14-8)20(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405862
(CHEMBL5270755)Show InChI InChI=1S/C11H15N2O6PS2/c1-3-17-20(14,18-4-2)19-8-5-6-9-10(7-8)21-11(13-9)22(12,15)16/h5-7H,3-4H2,1-2H3,(H2,12,15,16) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405863
(CHEMBL5284821)Show InChI InChI=1S/C9H8N2O4S2/c1-5(12)15-6-2-3-7-8(4-6)16-9(11-7)17(10,13)14/h2-4H,1H3,(H2,10,13,14) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405864
(CHEMBL5285314)Show InChI InChI=1S/C12H15N3O4S2/c1-12(2,3)10(16)19-7-5-4-6-9(8(7)13)20-11(15-6)21(14,17)18/h4-5H,13H2,1-3H3,(H2,14,17,18) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405865
(CHEMBL5286922)Show InChI InChI=1S/C12H14N2O4S2/c1-12(2,3)10(15)18-7-4-5-8-9(6-7)19-11(14-8)20(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405866
(CHEMBL5267725)Show SMILES CCOCCOCCOC(C)(C)C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C17H24N2O7S2/c1-4-23-7-8-24-9-10-25-17(2,3)15(20)26-12-5-6-13-14(11-12)27-16(19-13)28(18,21)22/h5-6,11H,4,7-10H2,1-3H3,(H2,18,21,22) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405850
(CHEMBL5273001)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,18-3)10(15)19-7-4-5-8-9(6-7)20-11(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405851
(CHEMBL5283686)Show SMILES COc1cccc(OC)c1C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C16H14N2O6S2/c1-22-11-4-3-5-12(23-2)14(11)15(19)24-9-6-7-10-13(8-9)25-16(18-10)26(17,20)21/h3-8H,1-2H3,(H2,17,20,21) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405853
(CHEMBL5273189)Show InChI InChI=1S/C12H14N2O5S2/c1-7(2)6-18-12(15)19-8-3-4-9-10(5-8)20-11(14-9)21(13,16)17/h3-5,7H,6H2,1-2H3,(H2,13,16,17) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405854
(CHEMBL5282587)Show InChI InChI=1S/C10H11N3O4S2/c1-13(2)10(14)17-6-3-4-7-8(5-6)18-9(12-7)19(11,15)16/h3-5H,1-2H3,(H2,11,15,16) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405867
(CHEMBL5283527)Show InChI InChI=1S/C13H16N2O5S2/c1-4-19-13(2,3)11(16)20-8-5-6-9-10(7-8)21-12(15-9)22(14,17)18/h5-7H,4H2,1-3H3,(H2,14,17,18) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405868
(CHEMBL5285121)Show SMILES NS(=O)(=O)c1nc2ccc(OC(=O)Cc3ccc(Cl)cc3)cc2s1 Show InChI InChI=1S/C15H11ClN2O4S2/c16-10-3-1-9(2-4-10)7-14(19)22-11-5-6-12-13(8-11)23-15(18-12)24(17,20)21/h1-6,8H,7H2,(H2,17,20,21) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405869
(CHEMBL5289588)Show SMILES NS(=O)(=O)c1nc2ccc(OC(=O)\C=C\c3ccccc3)cc2s1 Show InChI InChI=1S/C16H12N2O4S2/c17-24(20,21)16-18-13-8-7-12(10-14(13)23-16)22-15(19)9-6-11-4-2-1-3-5-11/h1-10H,(H2,17,20,21)/b9-6+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405855
(CHEMBL5267293)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,3)19-11(15)18-7-4-5-8-9(6-7)20-10(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405859
(CHEMBL5271818)Show InChI InChI=1S/C15H20N2O4S2/c1-2-3-4-5-6-7-14(18)21-11-8-9-12-13(10-11)22-15(17-12)23(16,19)20/h8-10H,2-7H2,1H3,(H2,16,19,20) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50405860
(CHEMBL5278170)Show SMILES CC(C)(C)C(=O)Nc1c(OC(=O)C(C)(C)C)ccc2nc(sc12)S(N)(=O)=O Show InChI InChI=1S/C17H23N3O5S2/c1-16(2,3)13(21)20-11-10(25-14(22)17(4,5)6)8-7-9-12(11)26-15(19-9)27(18,23)24/h7-8H,1-6H3,(H,20,21)(H2,18,23,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50405862
(CHEMBL5270755)Show InChI InChI=1S/C11H15N2O6PS2/c1-3-17-20(14,18-4-2)19-8-5-6-9-10(7-8)21-11(13-9)22(12,15)16/h5-7H,3-4H2,1-2H3,(H2,12,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405853
(CHEMBL5273189)Show InChI InChI=1S/C12H14N2O5S2/c1-7(2)6-18-12(15)19-8-3-4-9-10(5-8)20-11(14-9)21(13,16)17/h3-5,7H,6H2,1-2H3,(H2,13,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61535
(MLS000717682 | SMR000287487 | [4-(2,7-dimethyl-5,6...)Show SMILES CC1CCc2c(C1)sc1nc(C)nc(N3CCN(CC3)C(=O)c3ccco3)c21 Show InChI InChI=1S/C21H24N4O2S/c1-13-5-6-15-17(12-13)28-20-18(15)19(22-14(2)23-20)24-7-9-25(10-8-24)21(26)16-4-3-11-27-16/h3-4,11,13H,5-10,12H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61528
(MLS000862515 | N-(4-{[(3,4-dimethyl-5-isoxazolyl)a...)Show SMILES Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3cc(nc4c(C)cc(C)cc34)-c3cccnc3)cc2)c1C Show InChI InChI=1S/C28H25N5O4S/c1-16-12-17(2)26-23(13-16)24(14-25(31-26)20-6-5-11-29-15-20)27(34)30-21-7-9-22(10-8-21)38(35,36)33-28-18(3)19(4)32-37-28/h5-15,33H,1-4H3,(H,30,34) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405850
(CHEMBL5273001)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,18-3)10(15)19-7-4-5-8-9(6-7)20-11(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61427
(2-furanyl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzo...)Show SMILES Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C20H22N4O2S/c1-13-21-18(17-14-5-2-3-7-16(14)27-19(17)22-13)23-8-10-24(11-9-23)20(25)15-6-4-12-26-15/h4,6,12H,2-3,5,7-11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61399
(MLS000071807 | SMR000003886 | [4-(2-Cyclopropyl-5,...)Show SMILES O=C(N1CCN(CC1)c1nc(nc2sc3CCCCc3c12)C1CC1)c1ccco1 Show InChI InChI=1S/C22H24N4O2S/c27-22(16-5-3-13-28-16)26-11-9-25(10-12-26)20-18-15-4-1-2-6-17(15)29-21(18)24-19(23-20)14-7-8-14/h3,5,13-14H,1-2,4,6-12H2 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405870
(CHEMBL5275934)Show InChI InChI=1S/C11H12N2O4S2/c1-2-3-10(14)17-7-4-5-9-8(6-7)13-11(18-9)19(12,15)16/h4-6H,2-3H2,1H3,(H2,12,15,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405853
(CHEMBL5273189)Show InChI InChI=1S/C12H14N2O5S2/c1-7(2)6-18-12(15)19-8-3-4-9-10(5-8)20-11(14-9)21(13,16)17/h3-5,7H,6H2,1-2H3,(H2,13,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61427
(2-furanyl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzo...)Show SMILES Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C20H22N4O2S/c1-13-21-18(17-14-5-2-3-7-16(14)27-19(17)22-13)23-8-10-24(11-9-23)20(25)15-6-4-12-26-15/h4,6,12H,2-3,5,7-11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405861
(CHEMBL5278819)Show SMILES COCCOC(C)(C)C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C14H18N2O6S2/c1-14(2,21-7-6-20-3)12(17)22-9-4-5-10-11(8-9)23-13(16-10)24(15,18)19/h4-5,8H,6-7H2,1-3H3,(H2,15,18,19) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405852
(CHEMBL5281110)Show InChI InChI=1S/C11H12N2O4S2/c1-2-3-10(14)17-7-4-5-8-9(6-7)18-11(13-8)19(12,15)16/h4-6H,2-3H2,1H3,(H2,12,15,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405854
(CHEMBL5282587)Show InChI InChI=1S/C10H11N3O4S2/c1-13(2)10(14)17-6-3-4-7-8(5-6)18-9(12-7)19(11,15)16/h3-5H,1-2H3,(H2,11,15,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405859
(CHEMBL5271818)Show InChI InChI=1S/C15H20N2O4S2/c1-2-3-4-5-6-7-14(18)21-11-8-9-12-13(10-11)22-15(17-12)23(16,19)20/h8-10H,2-7H2,1H3,(H2,16,19,20) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405858
(CHEMBL5275607)Show SMILES CN(C)c1ccc(cc1)C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C16H15N3O4S2/c1-19(2)11-5-3-10(4-6-11)15(20)23-12-7-8-13-14(9-12)24-16(18-13)25(17,21)22/h3-9H,1-2H3,(H2,17,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 3.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405855
(CHEMBL5267293)Show InChI InChI=1S/C12H14N2O5S2/c1-12(2,3)19-11(15)18-7-4-5-8-9(6-7)20-10(14-8)21(13,16)17/h4-6H,1-3H3,(H2,13,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 7.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM61427
(2-furanyl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzo...)Show SMILES Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C20H22N4O2S/c1-13-21-18(17-14-5-2-3-7-16(14)27-19(17)22-13)23-8-10-24(11-9-23)20(25)15-6-4-12-26-15/h4,6,12H,2-3,5,7-11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of rat microsomal HMG-CoA reductase activity by 50% |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405860
(CHEMBL5278170)Show SMILES CC(C)(C)C(=O)Nc1c(OC(=O)C(C)(C)C)ccc2nc(sc12)S(N)(=O)=O Show InChI InChI=1S/C17H23N3O5S2/c1-16(2,3)13(21)20-11-10(25-14(22)17(4,5)6)8-7-9-12(11)26-15(19-9)27(18,23)24/h7-8H,1-6H3,(H,20,21)(H2,18,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405851
(CHEMBL5283686)Show SMILES COc1cccc(OC)c1C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C16H14N2O6S2/c1-22-11-4-3-5-12(23-2)14(11)15(19)24-9-6-7-10-13(8-9)25-16(18-10)26(17,20)21/h3-8H,1-2H3,(H2,17,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 9.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405856
(CHEMBL5267388)Show InChI InChI=1S/C11H14N2O5S3/c1-2-3-6-18-21(16,17)8-4-5-9-10(7-8)19-11(13-9)20(12,14)15/h4-5,7H,2-3,6H2,1H3,(H2,12,14,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig |
Citation and Details
|
More data for this Ligand-Target Pair | |
G-protein coupled receptor 55
(Homo sapiens (Human)) | BDBM50405857
(CHEMBL5281025)Show SMILES CN(C)Cc1ccc(cc1)C(=O)Oc1ccc2nc(sc2c1)S(N)(=O)=O Show InChI InChI=1S/C17H17N3O4S2/c1-20(2)10-11-3-5-12(6-4-11)16(21)24-13-7-8-14-15(9-13)25-17(19-14)26(18,22)23/h3-9H,10H2,1-2H3,(H2,18,22,23) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at histamine H1 receptor against histamine in isolated ileum of guinea pig. |
Citation and Details
|
More data for this Ligand-Target Pair | |