Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50019918 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208859
((S)-3-(4-(3,5-diphenethylcinnamyloxy)phenyl)-2-eth...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(CCc3ccccc3)cc(CCc3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C36H38O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-14,19-22,24-26,35H,2,15-18,23,27H2,1H3,(H,37,38)/b14-9+/t35-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208863
((S)-3-(4-(3,5-diisopropoxycinnamyloxy)phenyl)-2-et...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(C)C)cc(OC(C)C)c2)cc1)C(O)=O Show InChI InChI=1S/C26H34O6/c1-6-29-25(26(27)28)16-20-9-11-22(12-10-20)30-13-7-8-21-14-23(31-18(2)3)17-24(15-21)32-19(4)5/h7-12,14-15,17-19,25H,6,13,16H2,1-5H3,(H,27,28)/b8-7+/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208860
((S)-3-(4-(3,5-bis(benzoyloxy)cinnamyloxy)phenyl)-2...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(=O)c3ccccc3)cc(OC(=O)c3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C34H30O8/c1-2-39-31(32(35)36)22-24-15-17-28(18-16-24)40-19-9-10-25-20-29(41-33(37)26-11-5-3-6-12-26)23-30(21-25)42-34(38)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,35,36)/b10-9+/t31-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208861
((S)-3-(4-(3,5-dibromocinnamyloxy)phenyl)-2-ethoxyp...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(Br)cc(Br)c2)cc1)C(O)=O Show InChI InChI=1S/C20H20Br2O4/c1-2-25-19(20(23)24)12-14-5-7-18(8-6-14)26-9-3-4-15-10-16(21)13-17(22)11-15/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,23,24)/b4-3+/t19-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208862
((S)-2-ethoxy-3-[4-(3-[1,1';3',1'']terphenyl-5'-yl-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)-c2ccccc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)22-24-15-17-30(18-16-24)36-19-9-10-25-20-28(26-11-5-3-6-12-26)23-29(21-25)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,33,34)/b10-9+/t31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50161659
((S)-2-Ethoxy-3-[4-((E)-3-phenyl-allyloxy)-phenyl]-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C20H22O4/c1-2-23-19(20(21)22)15-17-10-12-18(13-11-17)24-14-6-9-16-7-4-3-5-8-16/h3-13,19H,2,14-15H2,1H3,(H,21,22)/b9-6+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208863
((S)-3-(4-(3,5-diisopropoxycinnamyloxy)phenyl)-2-et...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(C)C)cc(OC(C)C)c2)cc1)C(O)=O Show InChI InChI=1S/C26H34O6/c1-6-29-25(26(27)28)16-20-9-11-22(12-10-20)30-13-7-8-21-14-23(31-18(2)3)17-24(15-21)32-19(4)5/h7-12,14-15,17-19,25H,6,13,16H2,1-5H3,(H,27,28)/b8-7+/t25-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208864
((E)-(S)-3-(4-{3-[3,5-bis-(2,2,2-trifluoro-ethoxy)-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC(F)(F)F)cc(OCC(F)(F)F)c2)cc1)C(O)=O Show InChI InChI=1S/C24H24F6O6/c1-2-33-21(22(31)32)12-16-5-7-18(8-6-16)34-9-3-4-17-10-19(35-14-23(25,26)27)13-20(11-17)36-15-24(28,29)30/h3-8,10-11,13,21H,2,9,12,14-15H2,1H3,(H,31,32)/b4-3+/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208865
((S)-3-(4-(3,5-diethoxycinnamyloxy)phenyl)-2-ethoxy...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC)cc(OCC)c2)cc1)C(O)=O Show InChI InChI=1S/C24H30O6/c1-4-27-21-14-19(15-22(17-21)28-5-2)8-7-13-30-20-11-9-18(10-12-20)16-23(24(25)26)29-6-3/h7-12,14-15,17,23H,4-6,13,16H2,1-3H3,(H,25,26)/b8-7+/t23-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208864
((E)-(S)-3-(4-{3-[3,5-bis-(2,2,2-trifluoro-ethoxy)-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC(F)(F)F)cc(OCC(F)(F)F)c2)cc1)C(O)=O Show InChI InChI=1S/C24H24F6O6/c1-2-33-21(22(31)32)12-16-5-7-18(8-6-16)34-9-3-4-17-10-19(35-14-23(25,26)27)13-20(11-17)36-15-24(28,29)30/h3-8,10-11,13,21H,2,9,12,14-15H2,1H3,(H,31,32)/b4-3+/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208866
((S)-3-(4-(3,5-distyrylcinnamyloxy)phenyl)-2-ethoxy...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(\C=C\c3ccccc3)cc(\C=C\c3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C36H34O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-22,24-26,35H,2,23,27H2,1H3,(H,37,38)/b14-9+,17-15+,18-16+/t35-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208867
((S)-3-{4-[3-(4,4''-Di-tert-butyl-[1,1';3',1'']terp...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)-c2ccc(cc2)C(C)(C)C)-c2ccc(cc2)C(C)(C)C)cc1)C(O)=O Show InChI InChI=1S/C40H46O4/c1-8-43-37(38(41)42)26-28-11-21-36(22-12-28)44-23-9-10-29-24-32(30-13-17-34(18-14-30)39(2,3)4)27-33(25-29)31-15-19-35(20-16-31)40(5,6)7/h9-22,24-25,27,37H,8,23,26H2,1-7H3,(H,41,42)/b10-9+/t37-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208867
((S)-3-{4-[3-(4,4''-Di-tert-butyl-[1,1';3',1'']terp...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)-c2ccc(cc2)C(C)(C)C)-c2ccc(cc2)C(C)(C)C)cc1)C(O)=O Show InChI InChI=1S/C40H46O4/c1-8-43-37(38(41)42)26-28-11-21-36(22-12-28)44-23-9-10-29-24-32(30-13-17-34(18-14-30)39(2,3)4)27-33(25-29)31-15-19-35(20-16-31)40(5,6)7/h9-22,24-25,27,37H,8,23,26H2,1-7H3,(H,41,42)/b10-9+/t37-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208869
((S)-3-(4-(3,5-bis(cyclopentyloxy)cinnamyloxy)pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC3CCCC3)cc(OC3CCCC3)c2)cc1)C(O)=O Show InChI InChI=1S/C30H38O6/c1-2-33-29(30(31)32)20-22-13-15-24(16-14-22)34-17-7-8-23-18-27(35-25-9-3-4-10-25)21-28(19-23)36-26-11-5-6-12-26/h7-8,13-16,18-19,21,25-26,29H,2-6,9-12,17,20H2,1H3,(H,31,32)/b8-7+/t29-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208863
((S)-3-(4-(3,5-diisopropoxycinnamyloxy)phenyl)-2-et...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(C)C)cc(OC(C)C)c2)cc1)C(O)=O Show InChI InChI=1S/C26H34O6/c1-6-29-25(26(27)28)16-20-9-11-22(12-10-20)30-13-7-8-21-14-23(31-18(2)3)17-24(15-21)32-19(4)5/h7-12,14-15,17-19,25H,6,13,16H2,1-5H3,(H,27,28)/b8-7+/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50134842
((S)-3-[4-((E)-3-Biphenyl-4-yl-but-2-enyloxy)-pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/C)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C27H28O4/c1-3-30-26(27(28)29)19-21-9-15-25(16-10-21)31-18-17-20(2)22-11-13-24(14-12-22)23-7-5-4-6-8-23/h4-17,26H,3,18-19H2,1-2H3,(H,28,29)/b20-17+/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208868
((S)-3-(4-(3,5-bis(2-phenylethynyl)cinnamyloxy)phen...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C#Cc2ccccc2)C#Cc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C36H30O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-14,19-22,24-26,35H,2,23,27H2,1H3,(H,37,38)/b14-9+/t35-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50161659
((S)-2-Ethoxy-3-[4-((E)-3-phenyl-allyloxy)-phenyl]-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C20H22O4/c1-2-23-19(20(21)22)15-17-10-12-18(13-11-17)24-14-6-9-16-7-4-3-5-8-16/h3-13,19H,2,14-15H2,1H3,(H,21,22)/b9-6+/t19-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM24566
(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208864
((E)-(S)-3-(4-{3-[3,5-bis-(2,2,2-trifluoro-ethoxy)-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC(F)(F)F)cc(OCC(F)(F)F)c2)cc1)C(O)=O Show InChI InChI=1S/C24H24F6O6/c1-2-33-21(22(31)32)12-16-5-7-18(8-6-16)34-9-3-4-17-10-19(35-14-23(25,26)27)13-20(11-17)36-15-24(28,29)30/h3-8,10-11,13,21H,2,9,12,14-15H2,1H3,(H,31,32)/b4-3+/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208868
((S)-3-(4-(3,5-bis(2-phenylethynyl)cinnamyloxy)phen...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C#Cc2ccccc2)C#Cc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C36H30O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-14,19-22,24-26,35H,2,23,27H2,1H3,(H,37,38)/b14-9+/t35-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208860
((S)-3-(4-(3,5-bis(benzoyloxy)cinnamyloxy)phenyl)-2...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(=O)c3ccccc3)cc(OC(=O)c3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C34H30O8/c1-2-39-31(32(35)36)22-24-15-17-28(18-16-24)40-19-9-10-25-20-29(41-33(37)26-11-5-3-6-12-26)23-30(21-25)42-34(38)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,35,36)/b10-9+/t31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208871
((S)-3-(4-(3,5-dimethoxycinnamyloxy)phenyl)-2-ethox...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC)cc(OC)c2)cc1)C(O)=O Show InChI InChI=1S/C22H26O6/c1-4-27-21(22(23)24)14-16-7-9-18(10-8-16)28-11-5-6-17-12-19(25-2)15-20(13-17)26-3/h5-10,12-13,15,21H,4,11,14H2,1-3H3,(H,23,24)/b6-5+/t21-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM24566
(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208865
((S)-3-(4-(3,5-diethoxycinnamyloxy)phenyl)-2-ethoxy...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC)cc(OCC)c2)cc1)C(O)=O Show InChI InChI=1S/C24H30O6/c1-4-27-21-14-19(15-22(17-21)28-5-2)8-7-13-30-20-11-9-18(10-12-20)16-23(24(25)26)29-6-3/h7-12,14-15,17,23H,4-6,13,16H2,1-3H3,(H,25,26)/b8-7+/t23-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208869
((S)-3-(4-(3,5-bis(cyclopentyloxy)cinnamyloxy)pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC3CCCC3)cc(OC3CCCC3)c2)cc1)C(O)=O Show InChI InChI=1S/C30H38O6/c1-2-33-29(30(31)32)20-22-13-15-24(16-14-22)34-17-7-8-23-18-27(35-25-9-3-4-10-25)21-28(19-23)36-26-11-5-6-12-26/h7-8,13-16,18-19,21,25-26,29H,2-6,9-12,17,20H2,1H3,(H,31,32)/b8-7+/t29-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208866
((S)-3-(4-(3,5-distyrylcinnamyloxy)phenyl)-2-ethoxy...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(\C=C\c3ccccc3)cc(\C=C\c3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C36H34O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-22,24-26,35H,2,23,27H2,1H3,(H,37,38)/b14-9+,17-15+,18-16+/t35-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50134842
((S)-3-[4-((E)-3-Biphenyl-4-yl-but-2-enyloxy)-pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/C)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C27H28O4/c1-3-30-26(27(28)29)19-21-9-15-25(16-10-21)31-18-17-20(2)22-11-13-24(14-12-22)23-7-5-4-6-8-23/h4-17,26H,3,18-19H2,1-2H3,(H,28,29)/b20-17+/t26-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208870
((S)-3-(4-(3,5-bis(trifluoromethyl)cinnamyloxy)phen...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C22H20F6O4/c1-2-31-19(20(29)30)12-14-5-7-18(8-6-14)32-9-3-4-15-10-16(21(23,24)25)13-17(11-15)22(26,27)28/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,29,30)/b4-3+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208871
((S)-3-(4-(3,5-dimethoxycinnamyloxy)phenyl)-2-ethox...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC)cc(OC)c2)cc1)C(O)=O Show InChI InChI=1S/C22H26O6/c1-4-27-21(22(23)24)14-16-7-9-18(10-8-16)28-11-5-6-17-12-19(25-2)15-20(13-17)26-3/h5-10,12-13,15,21H,4,11,14H2,1-3H3,(H,23,24)/b6-5+/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 60 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208861
((S)-3-(4-(3,5-dibromocinnamyloxy)phenyl)-2-ethoxyp...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(Br)cc(Br)c2)cc1)C(O)=O Show InChI InChI=1S/C20H20Br2O4/c1-2-25-19(20(23)24)12-14-5-7-18(8-6-14)26-9-3-4-15-10-16(21)13-17(22)11-15/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,23,24)/b4-3+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208862
((S)-2-ethoxy-3-[4-(3-[1,1';3',1'']terphenyl-5'-yl-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)-c2ccccc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)22-24-15-17-30(18-16-24)36-19-9-10-25-20-28(26-11-5-3-6-12-26)23-29(21-25)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,33,34)/b10-9+/t31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208869
((S)-3-(4-(3,5-bis(cyclopentyloxy)cinnamyloxy)pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC3CCCC3)cc(OC3CCCC3)c2)cc1)C(O)=O Show InChI InChI=1S/C30H38O6/c1-2-33-29(30(31)32)20-22-13-15-24(16-14-22)34-17-7-8-23-18-27(35-25-9-3-4-10-25)21-28(19-23)36-26-11-5-6-12-26/h7-8,13-16,18-19,21,25-26,29H,2-6,9-12,17,20H2,1H3,(H,31,32)/b8-7+/t29-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208865
((S)-3-(4-(3,5-diethoxycinnamyloxy)phenyl)-2-ethoxy...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OCC)cc(OCC)c2)cc1)C(O)=O Show InChI InChI=1S/C24H30O6/c1-4-27-21-14-19(15-22(17-21)28-5-2)8-7-13-30-20-11-9-18(10-12-20)16-23(24(25)26)29-6-3/h7-12,14-15,17,23H,4-6,13,16H2,1-3H3,(H,25,26)/b8-7+/t23-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50161659
((S)-2-Ethoxy-3-[4-((E)-3-phenyl-allyloxy)-phenyl]-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C20H22O4/c1-2-23-19(20(21)22)15-17-10-12-18(13-11-17)24-14-6-9-16-7-4-3-5-8-16/h3-13,19H,2,14-15H2,1H3,(H,21,22)/b9-6+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208870
((S)-3-(4-(3,5-bis(trifluoromethyl)cinnamyloxy)phen...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C22H20F6O4/c1-2-31-19(20(29)30)12-14-5-7-18(8-6-14)32-9-3-4-15-10-16(21(23,24)25)13-17(11-15)22(26,27)28/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,29,30)/b4-3+/t19-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50134842
((S)-3-[4-((E)-3-Biphenyl-4-yl-but-2-enyloxy)-pheny...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C(/C)c2ccc(cc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C27H28O4/c1-3-30-26(27(28)29)19-21-9-15-25(16-10-21)31-18-17-20(2)22-11-13-24(14-12-22)23-7-5-4-6-8-23/h4-17,26H,3,18-19H2,1-2H3,(H,28,29)/b20-17+/t26-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208871
((S)-3-(4-(3,5-dimethoxycinnamyloxy)phenyl)-2-ethox...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC)cc(OC)c2)cc1)C(O)=O Show InChI InChI=1S/C22H26O6/c1-4-27-21(22(23)24)14-16-7-9-18(10-8-16)28-11-5-6-17-12-19(25-2)15-20(13-17)26-3/h5-10,12-13,15,21H,4,11,14H2,1-3H3,(H,23,24)/b6-5+/t21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208860
((S)-3-(4-(3,5-bis(benzoyloxy)cinnamyloxy)phenyl)-2...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(OC(=O)c3ccccc3)cc(OC(=O)c3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C34H30O8/c1-2-39-31(32(35)36)22-24-15-17-28(18-16-24)40-19-9-10-25-20-29(41-33(37)26-11-5-3-6-12-26)23-30(21-25)42-34(38)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,35,36)/b10-9+/t31-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208859
((S)-3-(4-(3,5-diphenethylcinnamyloxy)phenyl)-2-eth...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(CCc3ccccc3)cc(CCc3ccccc3)c2)cc1)C(O)=O Show InChI InChI=1S/C36H38O4/c1-2-39-35(36(37)38)27-30-19-21-34(22-20-30)40-23-9-14-31-24-32(17-15-28-10-5-3-6-11-28)26-33(25-31)18-16-29-12-7-4-8-13-29/h3-14,19-22,24-26,35H,2,15-18,23,27H2,1H3,(H,37,38)/b14-9+/t35-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50208862
((S)-2-ethoxy-3-[4-(3-[1,1';3',1'']terphenyl-5'-yl-...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)-c2ccccc2)-c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C32H30O4/c1-2-35-31(32(33)34)22-24-15-17-30(18-16-24)36-19-9-10-25-20-28(26-11-5-3-6-12-26)23-29(21-25)27-13-7-4-8-14-27/h3-18,20-21,23,31H,2,19,22H2,1H3,(H,33,34)/b10-9+/t31-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50208870
((S)-3-(4-(3,5-bis(trifluoromethyl)cinnamyloxy)phen...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C22H20F6O4/c1-2-31-19(20(29)30)12-14-5-7-18(8-6-14)32-9-3-4-15-10-16(21(23,24)25)13-17(11-15)22(26,27)28/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,29,30)/b4-3+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50208861
((S)-3-(4-(3,5-dibromocinnamyloxy)phenyl)-2-ethoxyp...)Show SMILES CCO[C@@H](Cc1ccc(OC\C=C\c2cc(Br)cc(Br)c2)cc1)C(O)=O Show InChI InChI=1S/C20H20Br2O4/c1-2-25-19(20(23)24)12-14-5-7-18(8-6-14)26-9-3-4-15-10-16(21)13-17(22)11-15/h3-8,10-11,13,19H,2,9,12H2,1H3,(H,23,24)/b4-3+/t19-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha by transactivation assay |
Bioorg Med Chem Lett 17: 3198-202 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.015 BindingDB Entry DOI: 10.7270/Q2154GQC |
More data for this Ligand-Target Pair | |