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TargetPeroxisome proliferator-activated receptor delta
LigandBDBM50208870
Substrate/Competitorn/a
Meas. Tech.ChEMBL_455160 (CHEMBL887190)
EC50 1400±n/a nM
Citation Sauerberg, P; Mogensen, JP; Jeppesen, L; Bury, PS; Fleckner, J; Olsen, GS; Jeppesen, CB; Wulff, EM; Pihera, P; Havranek, M; Polivka, Z; Pettersson, I Design of potent PPARalpha agonists. Bioorg Med Chem Lett17:3198-202 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peroxisome proliferator-activated receptor delta
Name:Peroxisome proliferator-activated receptor delta
Synonyms:NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:Enzyme
Mol. Mass.:49910.45
Organism:Homo sapiens (Human)
Description:Q03181
Residue:441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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  Blast E-value cutoff:
BDBM50208870
n/a
NameBDBM50208870
Synonyms:(S)-3-(4-(3,5-bis(trifluoromethyl)cinnamyloxy)phenyl)-2-ethoxypropanoic acid | CHEMBL248112
TypeSmall organic molecule
Emp. Form.C22H20F6O4
Mol. Mass.462.3822
SMILESCCO[C@@H](Cc1ccc(OC\C=C\c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(O)=O
Structure
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