Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50033964 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354672
(CHEMBL1834453)Show InChI InChI=1S/C16H15BrFN5OS/c17-11-2-1-9(18)7-13(11)24-10-3-5-23(6-4-10)16-20-8-12-14(22-16)25-15(19)21-12/h1-2,7-8,10H,3-6H2,(H2,19,21) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354682
(CHEMBL1834455)Show InChI InChI=1S/C16H15BrFN5O/c17-12-2-1-10(18)7-13(12)24-11-3-5-23(6-4-11)16-14-15(20-8-19-14)21-9-22-16/h1-2,7-9,11H,3-6H2,(H,19,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354677
(CHEMBL1834443)Show SMILES OCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4O3S/c19-18(20,21)11-3-1-2-4-12(11)28-10-5-7-25(8-6-10)17-24-15-14(29-17)16(27)23-13(9-26)22-15/h1-4,10,26H,5-9H2,(H,22,23,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354671
(CHEMBL1834452)Show InChI InChI=1S/C16H15BrFN5O/c17-12-2-1-10(18)7-14(12)24-11-3-5-23(6-4-11)16-19-8-13-15(22-16)21-9-20-13/h1-2,7-9,11H,3-6H2,(H,19,20,21,22) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354674
(CHEMBL1834457)Show SMILES OC(=O)CNc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H17BrFN5O3S/c19-12-2-1-10(20)7-14(12)28-11-3-5-25(6-4-11)17-21-8-13-16(24-17)29-18(23-13)22-9-15(26)27/h1-2,7-8,11H,3-6,9H2,(H,22,23)(H,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354676
(CHEMBL1834262)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2nc[nH]c(=O)c2s1 Show InChI InChI=1S/C17H15F3N4O2S/c18-17(19,20)11-3-1-2-4-12(11)26-10-5-7-24(8-6-10)16-23-14-13(27-16)15(25)22-9-21-14/h1-4,9-10H,5-8H2,(H,21,22,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354667
(CHEMBL1834456)Show SMILES OC(=O)COc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H16BrFN4O4S/c19-12-2-1-10(20)7-14(12)28-11-3-5-24(6-4-11)17-21-8-13-16(23-17)29-18(22-13)27-9-15(25)26/h1-2,7-8,11H,3-6,9H2,(H,25,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354684
(CHEMBL1834442)Show SMILES Cc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4O2S/c1-10-22-15-14(16(26)23-10)28-17(24-15)25-8-6-11(7-9-25)27-13-5-3-2-4-12(13)18(19,20)21/h2-5,11H,6-9H2,1H3,(H,22,23,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354673
(CHEMBL1834454)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C17H16F3N5O/c18-17(19,20)12-3-1-2-4-13(12)26-11-5-7-25(8-6-11)16-14-15(22-9-21-14)23-10-24-16/h1-4,9-11H,5-8H2,(H,21,22,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354670
(CHEMBL1834451)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc2[nH]cnc2n1 Show InChI InChI=1S/C17H16F3N5O/c18-17(19,20)12-3-1-2-4-14(12)26-11-5-7-25(8-6-11)16-21-9-13-15(24-16)23-10-22-13/h1-4,9-11H,5-8H2,(H,21,22,23,24) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354677
(CHEMBL1834443)Show SMILES OCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4O3S/c19-18(20,21)11-3-1-2-4-12(11)28-10-5-7-25(8-6-10)17-24-15-14(29-17)16(27)23-13(9-26)22-15/h1-4,10,26H,5-9H2,(H,22,23,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354672
(CHEMBL1834453)Show InChI InChI=1S/C16H15BrFN5OS/c17-11-2-1-9(18)7-13(11)24-10-3-5-23(6-4-10)16-20-8-12-14(22-16)25-15(19)21-12/h1-2,7-8,10H,3-6H2,(H2,19,21) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354676
(CHEMBL1834262)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2nc[nH]c(=O)c2s1 Show InChI InChI=1S/C17H15F3N4O2S/c18-17(19,20)11-3-1-2-4-12(11)26-10-5-7-24(8-6-10)16-23-14-13(27-16)15(25)22-9-21-14/h1-4,9-10H,5-8H2,(H,21,22,25) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354668
(CHEMBL1834449)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc2[nH]c(=O)[nH]c2n1 Show InChI InChI=1S/C17H16F3N5O2/c18-17(19,20)11-3-1-2-4-13(11)27-10-5-7-25(8-6-10)15-21-9-12-14(23-15)24-16(26)22-12/h1-4,9-10H,5-8H2,(H2,21,22,23,24,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354681
(CHEMBL1834447)Show SMILES Nc1ncnc2nc([nH]c12)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H17F3N6O/c18-17(19,20)11-3-1-2-4-12(11)27-10-5-7-26(8-6-10)16-24-13-14(21)22-9-23-15(13)25-16/h1-4,9-10H,5-8H2,(H3,21,22,23,24,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354671
(CHEMBL1834452)Show InChI InChI=1S/C16H15BrFN5O/c17-12-2-1-10(18)7-14(12)24-11-3-5-23(6-4-11)16-19-8-13-15(22-16)21-9-20-13/h1-2,7-9,11H,3-6H2,(H,19,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354673
(CHEMBL1834454)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C17H16F3N5O/c18-17(19,20)12-3-1-2-4-13(12)26-11-5-7-25(8-6-11)16-14-15(22-9-21-14)23-10-24-16/h1-4,9-11H,5-8H2,(H,21,22,23,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354667
(CHEMBL1834456)Show SMILES OC(=O)COc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H16BrFN4O4S/c19-12-2-1-10(20)7-14(12)28-11-3-5-24(6-4-11)17-21-8-13-16(23-17)29-18(22-13)27-9-15(25)26/h1-2,7-8,11H,3-6,9H2,(H,25,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354680
(CHEMBL1834446)Show SMILES Cc1ncc2sc(nc2n1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4OS/c1-11-22-10-15-16(23-11)24-17(27-15)25-8-6-12(7-9-25)26-14-5-3-2-4-13(14)18(19,20)21/h2-5,10,12H,6-9H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354678
(CHEMBL1834444)Show SMILES Nc1ncnc2nc(sc12)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H16F3N5OS/c18-17(19,20)11-3-1-2-4-12(11)26-10-5-7-25(8-6-10)16-24-15-13(27-16)14(21)22-9-23-15/h1-4,9-10H,5-8H2,(H2,21,22,23) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354684
(CHEMBL1834442)Show SMILES Cc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4O2S/c1-10-22-15-14(16(26)23-10)28-17(24-15)25-8-6-11(7-9-25)27-13-5-3-2-4-12(13)18(19,20)21/h2-5,11H,6-9H2,1H3,(H,22,23,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354679
(CHEMBL1834445)Show InChI InChI=1S/C18H16F3N3OS/c19-18(20,21)13-4-1-2-5-14(13)25-12-7-10-24(11-8-12)17-23-16-15(26-17)6-3-9-22-16/h1-6,9,12H,7-8,10-11H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354675
(CHEMBL1834441)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2cc[nH]c(=O)c2s1 Show InChI InChI=1S/C18H16F3N3O2S/c19-18(20,21)12-3-1-2-4-14(12)26-11-6-9-24(10-7-11)17-23-13-5-8-22-16(25)15(13)27-17/h1-5,8,11H,6-7,9-10H2,(H,22,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354683
(CHEMBL1834448)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2nc[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C17H16F3N5O2/c18-17(19,20)11-3-1-2-4-12(11)27-10-5-7-25(8-6-10)16-23-14-13(15(26)24-16)21-9-22-14/h1-4,9-10H,5-8H2,(H2,21,22,23,24,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354674
(CHEMBL1834457)Show SMILES OC(=O)CNc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H17BrFN5O3S/c19-12-2-1-10(20)7-14(12)28-11-3-5-25(6-4-11)17-21-8-13-16(24-17)29-18(23-13)22-9-15(26)27/h1-2,7-8,11H,3-6,9H2,(H,22,23)(H,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in rat Hep cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354681
(CHEMBL1834447)Show SMILES Nc1ncnc2nc([nH]c12)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H17F3N6O/c18-17(19,20)11-3-1-2-4-12(11)27-10-5-7-26(8-6-10)16-24-13-14(21)22-9-23-15(13)25-16/h1-4,9-10H,5-8H2,(H3,21,22,23,24,25) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in rat Hep cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354674
(CHEMBL1834457)Show SMILES OC(=O)CNc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H17BrFN5O3S/c19-12-2-1-10(20)7-14(12)28-11-3-5-25(6-4-11)17-21-8-13-16(24-17)29-18(23-13)22-9-15(26)27/h1-2,7-8,11H,3-6,9H2,(H,22,23)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354680
(CHEMBL1834446)Show SMILES Cc1ncc2sc(nc2n1)N1CCC(CC1)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C18H17F3N4OS/c1-11-22-10-15-16(23-11)24-17(27-15)25-8-6-12(7-9-25)26-14-5-3-2-4-13(14)18(19,20)21/h2-5,10,12H,6-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354670
(CHEMBL1834451)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc2[nH]cnc2n1 Show InChI InChI=1S/C17H16F3N5O/c18-17(19,20)12-3-1-2-4-14(12)26-11-5-7-25(8-6-11)16-21-9-13-15(24-16)23-10-22-13/h1-4,9-11H,5-8H2,(H,21,22,23,24) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 266 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354675
(CHEMBL1834441)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2cc[nH]c(=O)c2s1 Show InChI InChI=1S/C18H16F3N3O2S/c19-18(20,21)12-3-1-2-4-14(12)26-11-6-9-24(10-7-11)17-23-13-5-8-22-16(25)15(13)27-17/h1-5,8,11H,6-7,9-10H2,(H,22,25) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 268 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354668
(CHEMBL1834449)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1ncc2[nH]c(=O)[nH]c2n1 Show InChI InChI=1S/C17H16F3N5O2/c18-17(19,20)11-3-1-2-4-13(11)27-10-5-7-25(8-6-10)15-21-9-12-14(23-15)24-16(26)22-12/h1-4,9-10H,5-8H2,(H2,21,22,23,24,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 319 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354667
(CHEMBL1834456)Show SMILES OC(=O)COc1nc2cnc(nc2s1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C18H16BrFN4O4S/c19-12-2-1-10(20)7-14(12)28-11-3-5-24(6-4-11)17-21-8-13-16(23-17)29-18(22-13)27-9-15(25)26/h1-2,7-8,11H,3-6,9H2,(H,25,26) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in rat Hep cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354683
(CHEMBL1834448)Show SMILES FC(F)(F)c1ccccc1OC1CCN(CC1)c1nc2nc[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C17H16F3N5O2/c18-17(19,20)11-3-1-2-4-12(11)27-10-5-7-25(8-6-10)16-23-14-13(15(26)24-16)21-9-22-14/h1-4,9-10H,5-8H2,(H2,21,22,23,24,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 378 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50354669
(CHEMBL1834450)Show InChI InChI=1S/C18H16BrFN2OS/c19-14-6-5-12(20)11-16(14)23-13-7-9-22(10-8-13)18-21-15-3-1-2-4-17(15)24-18/h1-6,11,13H,7-10H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 477 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 in rat liver microsome |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354679
(CHEMBL1834445)Show InChI InChI=1S/C18H16F3N3OS/c19-18(20,21)13-4-1-2-5-14(13)25-12-7-10-24(11-8-12)17-23-16-15(26-17)6-3-9-22-16/h1-6,9,12H,7-8,10-11H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 755 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354669
(CHEMBL1834450)Show InChI InChI=1S/C18H16BrFN2OS/c19-14-6-5-12(20)11-16(14)23-13-7-9-22(10-8-13)18-21-15-3-1-2-4-17(15)24-18/h1-6,11,13H,7-10H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50354666
(CHEMBL1833979)Show SMILES OC(=O)CCc1nc2nc(sc2c(=O)[nH]1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C19H18BrFN4O4S/c20-12-2-1-10(21)9-13(12)29-11-5-7-25(8-6-11)19-24-17-16(30-19)18(28)23-14(22-17)3-4-15(26)27/h1-2,9,11H,3-8H2,(H,26,27)(H,22,23,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human HepG2 cells |
Bioorg Med Chem Lett 21: 5692-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.08.037
BindingDB Entry DOI: 10.7270/Q2W959K1 |
More data for this
Ligand-Target Pair | |
Search and Browse
