Compile Data Set for Download or QSAR

Found 189 hits Enz. Inhib. hit(s) with all data for entry = 50036333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369022 (CHEMBL1788197) Show SMILES CCCN(CCCc1ccccc1)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035336 (8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-b...) Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C24H28N2O/c1-2-13-26(14-12-18-6-4-3-5-7-18)21-10-8-19-9-11-23-24(22(19)15-21)20(17-27)16-25-23/h3-7,9,11,16-17,21,25H,2,8,10,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035342 (8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]in...) Show SMILES O=Cc1c[nH]c2ccc3CCC(Cc3c12)N1CCCC1 Show InChI InChI=1S/C17H20N2O/c20-11-13-10-18-16-6-4-12-3-5-14(9-15(12)17(13)16)19-7-1-2-8-19/h4,6,10-11,14,18H,1-3,5,7-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035363 (8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-t...) Show SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C22H26N2OS/c1-2-10-24(11-9-19-4-3-12-26-19)18-7-5-16-6-8-21-22(20(16)13-18)17(15-25)14-23-21/h3-4,6,8,12,14-15,18,23H,2,5,7,9-11,13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035320 ((+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035305 ((S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369020 (CHEMBL1788200) Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]ccc3c2C1 |r| Show InChI InChI=1S/C26H37N3O2/c1-4-13-28(14-5-6-15-29-24(30)17-26(2,3)18-25(29)31)20-9-7-19-8-10-23-21(11-12-27-23)22(19)16-20/h8,10-12,20,27H,4-7,9,13-18H2,1-3H3/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035303 ((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035366 (8-Azepan-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole...) Show SMILES O=Cc1c[nH]c2ccc3CCC(Cc3c12)N1CCCCCC1 Show InChI InChI=1S/C19H24N2O/c22-13-15-12-20-18-8-6-14-5-7-16(11-17(14)19(15)18)21-9-3-1-2-4-10-21/h6,8,12-13,16,20H,1-5,7,9-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035347 (8-(Allyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo...) Show SMILES CCCN(CC=C)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C19H24N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h3,6,8,12-13,16,20H,1,4-5,7,9-11H2,2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035353 (8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahy...) Show SMILES CCCN(CC1CC1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C20H26N2O/c1-2-9-22(12-14-3-4-14)17-7-5-15-6-8-19-20(18(15)10-17)16(13-23)11-21-19/h6,8,11,13-14,17,21H,2-5,7,9-10,12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035345 (CHEMBL71145 | Propyl-(6,7,8,9-tetrahydro-3H-benzo[...) Show SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C21H26N2S/c1-2-12-23(13-10-18-4-3-14-24-18)17-7-5-16-6-8-21-19(9-11-22-21)20(16)15-17/h3-4,6,8-9,11,14,17,22H,2,5,7,10,12-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035359 (8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahy...) Show SMILES CCCN(CCCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369016 (CHEMBL1788198) Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C27H37N3O3/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035350 (8-(Methyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benz...) Show SMILES CCCN(C)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C17H22N2O/c1-3-8-19(2)14-6-4-12-5-7-16-17(15(12)9-14)13(11-20)10-18-16/h5,7,10-11,14,18H,3-4,6,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035351 (CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...) Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035343 (8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7...) Show SMILES CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C25H29ClN2O2/c1-2-11-28(12-4-13-30-22-6-3-5-20(26)14-22)21-9-7-18-8-10-24-25(23(18)15-21)19(17-29)16-27-24/h3,5-6,8,10,14,16-17,21,27H,2,4,7,9,11-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035365 (8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]in...) Show SMILES C1CCN(C1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C16H20N2/c1-2-10-18(9-1)13-5-3-12-4-6-16-14(7-8-17-16)15(12)11-13/h4,6-8,13,17H,1-3,5,9-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50369022 (CHEMBL1788197) Show SMILES CCCN(CCCc1ccccc1)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035356 (8-Propylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole...) Show SMILES CCCNC1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C16H20N2O/c1-2-7-17-13-5-3-11-4-6-15-16(14(11)8-13)12(10-19)9-18-15/h4,6,9-10,13,17-18H,2-3,5,7-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369017 (CHEMBL1744039) Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C20H28N2O/c1-4-9-22(12-14(2)3)17-7-5-15-6-8-19-20(18(15)10-17)16(13-23)11-21-19/h6,8,11,13-14,17,21H,4-5,7,9-10,12H2,1-3H3/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035360 (8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7...) Show SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C26H32N2O2/c1-3-14-28(15-6-8-20-7-4-5-9-25(20)30-2)22-12-10-19-11-13-24-26(23(19)16-22)21(18-29)17-27-24/h4-5,7,9,11,13,17-18,22,27H,3,6,8,10,12,14-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035307 (CHEMBL302171 | Dipropyl-(S)-6,7,8,9-tetrahydro-3H-...) Show SMILES CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50453697 (CHEMBL2112317) Show SMILES O.CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C27H37N3O3.H2O/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23;/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3;1H2/t21-;/m0./s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369019 (CHEMBL1744040) Show SMILES CN(C)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C15H18N2O/c1-17(2)12-5-3-10-4-6-14-15(13(10)7-12)11(9-18)8-16-14/h4,6,8-9,12,16H,3,5,7H2,1-2H3/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50369019 (CHEMBL1744040) Show SMILES CN(C)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C15H18N2O/c1-17(2)12-5-3-10-4-6-14-15(13(10)7-12)11(9-18)8-16-14/h4,6,8-9,12,16H,3,5,7H2,1-2H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035352 (4,4-Dimethyl-1-{4-[propyl-(6,7,8,9-tetrahydro-3H-b...) Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C26H37N3O2/c1-4-13-28(14-5-6-15-29-24(30)17-26(2,3)18-25(29)31)20-9-7-19-8-10-23-21(11-12-27-23)22(19)16-20/h8,10-12,20,27H,4-7,9,13-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035341 (Benzyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol...) Show SMILES CCCN(Cc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C22H26N2/c1-2-14-24(16-17-6-4-3-5-7-17)19-10-8-18-9-11-22-20(12-13-23-22)21(18)15-19/h3-7,9,11-13,19,23H,2,8,10,14-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035363 (8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-t...) Show SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C22H26N2OS/c1-2-10-24(11-9-19-4-3-12-26-19)18-7-5-16-6-8-21-22(20(16)13-18)17(15-25)14-23-21/h3-4,6,8,12,14-15,18,23H,2,5,7,9-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035359 (8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahy...) Show SMILES CCCN(CCCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035358 (CHEMBL306197 | [3-(2-Methoxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C25H32N2O/c1-3-16-27(17-6-8-20-7-4-5-9-25(20)28-2)21-12-10-19-11-13-24-22(14-15-26-24)23(19)18-21/h4-5,7,9,11,13-15,21,26H,3,6,8,10,12,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035355 (CHEMBL69729 | Cyclopropylmethyl-propyl-(6,7,8,9-te...) Show SMILES CCCN(CC1CC1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C19H26N2/c1-2-11-21(13-14-3-4-14)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,2-5,7,11-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035338 (8-(Benzyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benz...) Show SMILES CCCN(Cc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C23H26N2O/c1-2-12-25(15-17-6-4-3-5-7-17)20-10-8-18-9-11-22-23(21(18)13-20)19(16-26)14-24-22/h3-7,9,11,14,16,20,24H,2,8,10,12-13,15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035336 (8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-b...) Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C24H28N2O/c1-2-13-26(14-12-18-6-4-3-5-7-18)21-10-8-19-9-11-23-24(22(19)15-21)20(17-27)16-25-23/h3-7,9,11,16-17,21,25H,2,8,10,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035337 (8-{[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-buty...) Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C27H37N3O3/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035358 (CHEMBL306197 | [3-(2-Methoxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C25H32N2O/c1-3-16-27(17-6-8-20-7-4-5-9-25(20)28-2)21-12-10-19-11-13-24-22(14-15-26-24)23(19)18-21/h4-5,7,9,11,13-15,21,26H,3,6,8,10,12,16-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035348 (CHEMBL305976 | Propyl-(6,7,8,9-tetrahydro-3H-benzo...) Show SMILES CCCNC1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C15H20N2/c1-2-8-16-12-5-3-11-4-6-15-13(7-9-17-15)14(11)10-12/h4,6-7,9,12,16-17H,2-3,5,8,10H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035329 ((+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indo...) Show SMILES CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035360 (8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7...) Show SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C26H32N2O2/c1-3-14-28(15-6-8-20-7-4-5-9-25(20)30-2)22-12-10-19-11-13-24-26(23(19)16-22)21(18-29)17-27-24/h4-5,7,9,11,13,17-18,22,27H,3,6,8,10,12,14-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035361 ((3-Phenyl-propyl)-(6,7,8,9-tetrahydro-3H-benzo[e]i...) Show SMILES C(CNCC1CCc2ccc3[nH]ccc3c2C1)Cc1ccccc1 Show InChI InChI=1S/C22H26N2/c1-2-5-17(6-3-1)7-4-13-23-16-18-8-9-19-10-11-22-20(12-14-24-22)21(19)15-18/h1-3,5-6,10-12,14,18,23-24H,4,7-9,13,15-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50369018 (CHEMBL1744041) Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 |r| Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035362 (Allyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-...) Show SMILES CCCN(CC=C)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C18H24N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h3,6,8-10,15,19H,1,4-5,7,11-13H2,2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035358 (CHEMBL306197 | [3-(2-Methoxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C25H32N2O/c1-3-16-27(17-6-8-20-7-4-5-9-25(20)28-2)21-12-10-19-11-13-24-22(14-15-26-24)23(19)18-21/h4-5,7,9,11,13-15,21,26H,3,6,8,10,12,16-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50369016 (CHEMBL1788198) Show SMILES CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 |r| Show InChI InChI=1S/C27H37N3O3/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50035343 (8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7...) Show SMILES CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 Show InChI InChI=1S/C25H29ClN2O2/c1-2-11-28(12-4-13-30-22-6-3-5-20(26)14-22)21-9-7-18-8-10-24-25(23(18)15-21)19(17-29)16-27-24/h3,5-6,8,10,14,16-17,21,27H,2,4,7,9,11-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50035330 (CHEMBL302172 | Dipropyl-(R)-6,7,8,9-tetrahydro-3H-...) Show SMILES CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50035345 (CHEMBL71145 | Propyl-(6,7,8,9-tetrahydro-3H-benzo[...) Show SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C21H26N2S/c1-2-12-23(13-10-18-4-3-14-24-18)17-7-5-16-6-8-21-19(9-11-22-21)20(16)15-17/h3-4,6,8-9,11,14,17,22H,2,5,7,10,12-13,15H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035345 (CHEMBL71145 | Propyl-(6,7,8,9-tetrahydro-3H-benzo[...) Show SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C21H26N2S/c1-2-12-23(13-10-18-4-3-14-24-18)17-7-5-16-6-8-21-19(9-11-22-21)20(16)15-17/h3-4,6,8-9,11,14,17,22H,2,5,7,10,12-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50035351 (CHEMBL72285 | Phenethyl-propyl-(6,7,8,9-tetrahydro...) Show SMILES CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1 Show InChI InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]U-86170 as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50369018 (CHEMBL1744041) Show SMILES CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 |r| Show InChI InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against cloned mammalian Dopamine receptor D2 expressed in CHO cells using [3H]U-86170 as radioligand				J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW
					More data for this Ligand-Target Pair

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