BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50037568
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50164448 ((2R)-2-amino-4-methylidenepentanedioic acid4-methy...) Show SMILES N[C@H](CC(=C)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50052398 ((2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid \|...) Show SMILES N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50038038 ((S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl...) Show SMILES N[C@@H](CCn1oc(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50138783 (4-((S)-Amino-carboxy-methyl)-phthalic acid \| 4-[am...) Show SMILES N[C@H](C(O)=O)c1ccc(C(O)=O)c(c1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50056272 ((1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50164445 (2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-pr...) Show SMILES N[C@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50053585 ((S)-4-(amino(carboxy)methyl)-2-hydroxybenzoic acid...) Show SMILES N[C@H](C(O)=O)c1ccc(C(O)=O)c(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM66976 ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...) Show SMILES N[C@]1(CC[C@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50052256 ((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...) Show SMILES N[C@H](C(O)=O)C12CC(C1)(C2)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Effective concentration against D309A mutant Metabotropic glutamate receptor 4				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50004863 ((+/-)-trans-ACPD \| (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50031702 ((2R,4S)-2-Amino-4-methyl-pentanedioic acid \| (4S)-...) Show SMILES C[C@@H](C[C@@H](N)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Effective concentration against Metabotropic glutamate receptor 4				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50052256 ((S)-3-(amino(carboxy)methyl)bicyclo[1.1.1]pentane-...) Show SMILES N[C@H](C(O)=O)C12CC(C1)(C2)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair