BindingDB PrimarySearch

null

SMILES: N[C@@H](CCP(O)(O)=O)C(O)=O

InChI Key: InChIKey=DDOQBQRIEWHWBT-VKHMYHEASA-N

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 97 hits for monomerid = 50007548
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu4 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
University Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	n/a	n/a
University Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at mGlu8 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 3585-95 (2007) Article DOI: 10.1021/jm070262c BindingDB Entry DOI: 10.7270/Q23R0SMQ
University Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay				J Med Chem 59: 914-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01333 BindingDB Entry DOI: 10.7270/Q2000408
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat mGlu6 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay				J Med Chem 59: 914-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01333 BindingDB Entry DOI: 10.7270/Q2000408
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat mGlu7 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay				J Med Chem 59: 914-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01333 BindingDB Entry DOI: 10.7270/Q2000408
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat mGlu8 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assay				J Med Chem 59: 914-24 (2016) Article DOI: 10.1021/acs.jmedchem.5b01333 BindingDB Entry DOI: 10.7270/Q2000408
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR2 in human				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Mus musculus)	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR4a in human				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR1c in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR4a in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR6 in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR7 in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR2 in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR7 in human				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
CNS Research Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 4				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.52E+5	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 7				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 2				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 5				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 1				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Effect on Metabotropic glutamate receptor 6				J Med Chem 40: 3700-5 (1997) Article DOI: 10.1021/jm9703597 BindingDB Entry DOI: 10.7270/Q2W66MF9
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Effective concentration against D309A mutant Metabotropic glutamate receptor 4				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					Assay Description Effective concentration against Metabotropic glutamate receptor 4				J Med Chem 48: 2534-47 (2005) Article DOI: 10.1021/jm049092j BindingDB Entry DOI: 10.7270/Q23X87FM
Universit£ Ren£ Descartes-Paris V Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Functional activity at rat mGluR4				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR6 by measuring cAMP formation in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human mGluR2 from BHK cells in [35S]GTP-gamma-S stimulation assay				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+5	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human mGluR7 by measuring cAMP formation in BHK cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cells				Bioorg Med Chem Lett 16: 196-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.014 BindingDB Entry DOI: 10.7270/Q2DZ0932
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentration				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentration				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Agonist activity at rat recombinant mGluR4 expressed in BHK cells				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.88E+5	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human recombinant mGluR7 expressed in BHK cells assessed as cAMP production				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Activity at rat recombinant mGluR6 expressed in CHO cells assessed as cAMP production				Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR
Universit£ di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.06E+5	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu8 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu6 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.49E+5	n/a	n/a	n/a	n/a
Universite Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGlu7 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...				J Med Chem 53: 2797-813 (2010) Article DOI: 10.1021/jm901523t BindingDB Entry DOI: 10.7270/Q28W3F7Q
Universite Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair

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