Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50038912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50185127 ((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...) Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O |r,t:18| Show InChI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297911 (CHEMBL550065 | N-butyl-4-[(3-chlorophenylsulfonami...) Show SMILES CCCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-3-17-28(23-10-6-4-5-7-11-23)25(29)21-15-13-20(14-16-21)19-27-32(30,31)24-12-8-9-22(26)18-24/h8-9,12-16,18,23,27H,2-7,10-11,17,19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297909 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H27ClN2O3S/c1-25(20-8-4-2-3-5-9-20)22(26)18-13-11-17(12-14-18)16-24-29(27,28)21-10-6-7-19(23)15-21/h6-7,10-15,20,24H,2-5,8-9,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297910 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-16-27(22-9-5-3-4-6-10-22)24(28)20-14-12-19(13-15-20)18-26-31(29,30)23-11-7-8-21(25)17-23/h7-8,11-15,17,22,26H,2-6,9-10,16,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297910 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-16-27(22-9-5-3-4-6-10-22)24(28)20-14-12-19(13-15-20)18-26-31(29,30)23-11-7-8-21(25)17-23/h7-8,11-15,17,22,26H,2-6,9-10,16,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50185127 ((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...) Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O |r,t:18| Show InChI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50185127 ((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...) Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O |r,t:18| Show InChI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297912 (4-[(3-Chlorophenylsulfonamido)methyl]-N-(1-adamant...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:24:25:22.23.28:29,THB:24:23:29:30.25.26,26:25:22:28.27.29,26:27:22:30.24.25| Show InChI InChI=1S/C24H27ClN2O3S/c25-21-2-1-3-22(11-21)31(29,30)26-15-16-4-6-20(7-5-16)23(28)27-24-12-17-8-18(13-24)10-19(9-17)14-24/h1-7,11,17-19,26H,8-10,12-15H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297912 (4-[(3-Chlorophenylsulfonamido)methyl]-N-(1-adamant...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:24:25:22.23.28:29,THB:24:23:29:30.25.26,26:25:22:28.27.29,26:27:22:30.24.25| Show InChI InChI=1S/C24H27ClN2O3S/c25-21-2-1-3-22(11-21)31(29,30)26-15-16-4-6-20(7-5-16)23(28)27-24-12-17-8-18(13-24)10-19(9-17)14-24/h1-7,11,17-19,26H,8-10,12-15H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297908 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCCC1 Show InChI InChI=1S/C21H25ClN2O3S/c22-18-6-5-9-20(14-18)28(26,27)23-15-16-10-12-17(13-11-16)21(25)24-19-7-3-1-2-4-8-19/h5-6,9-14,19,23H,1-4,7-8,15H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297911 (CHEMBL550065 | N-butyl-4-[(3-chlorophenylsulfonami...) Show SMILES CCCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-3-17-28(23-10-6-4-5-7-11-23)25(29)21-15-13-20(14-16-21)19-27-32(30,31)24-12-8-9-22(26)18-24/h8-9,12-16,18,23,27H,2-7,10-11,17,19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297908 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCCC1 Show InChI InChI=1S/C21H25ClN2O3S/c22-18-6-5-9-20(14-18)28(26,27)23-15-16-10-12-17(13-11-16)21(25)24-19-7-3-1-2-4-8-19/h5-6,9-14,19,23H,1-4,7-8,15H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50247012 (3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...) Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O |r,t:18| Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297921 (3-Chloro-N-[4-(piperidine-1-carbonyl)benzyl]benzen...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCCCC1 Show InChI InChI=1S/C19H21ClN2O3S/c20-17-5-4-6-18(13-17)26(24,25)21-14-15-7-9-16(10-8-15)19(23)22-11-2-1-3-12-22/h4-10,13,21H,1-3,11-12,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297906 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohexyl...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C20H23ClN2O3S/c21-17-5-4-8-19(13-17)27(25,26)22-14-15-9-11-16(12-10-15)20(24)23-18-6-2-1-3-7-18/h4-5,8-13,18,22H,1-3,6-7,14H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297905 (4-[(3-Chlorophenylsulfonamido)methyl]-N,N-diethylb...) Show SMILES CCN(CC)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C18H21ClN2O3S/c1-3-21(4-2)18(22)15-10-8-14(9-11-15)13-20-25(23,24)17-7-5-6-16(19)12-17/h5-12,20H,3-4,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	395	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297906 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohexyl...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C20H23ClN2O3S/c21-17-5-4-8-19(13-17)27(25,26)22-14-15-9-11-16(12-10-15)20(24)23-18-6-2-1-3-7-18/h4-5,8-13,18,22H,1-3,6-7,14H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297922 (3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benze...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C18H19ClN2O3S/c19-16-4-3-5-17(12-16)25(23,24)20-13-14-6-8-15(9-7-14)18(22)21-10-1-2-11-21/h3-9,12,20H,1-2,10-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297914 (3-chloro-N-(4-((2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-8-6-16(7-9-17)11-22-28(25,26)19-5-3-4-18(21)10-19/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	576	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297909 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H27ClN2O3S/c1-25(20-8-4-2-3-5-9-20)22(26)18-13-11-17(12-14-18)16-24-29(27,28)21-10-6-7-19(23)15-21/h6-7,10-15,20,24H,2-5,8-9,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	638	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297921 (3-Chloro-N-[4-(piperidine-1-carbonyl)benzyl]benzen...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCCCC1 Show InChI InChI=1S/C19H21ClN2O3S/c20-17-5-4-6-18(13-17)26(24,25)21-14-15-7-9-16(10-8-15)19(23)22-11-2-1-3-12-22/h4-10,13,21H,1-3,11-12,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	647	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297907 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclopenty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCC1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-4-3-7-18(12-16)26(24,25)21-13-14-8-10-15(11-9-14)19(23)22-17-5-1-2-6-17/h3-4,7-12,17,21H,1-2,5-6,13H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	732	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297918 (3-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C20H22ClFN2O4S/c1-13-11-24(12-14(2)28-13)20(25)16-5-3-15(4-6-16)10-23-29(26,27)17-7-8-19(22)18(21)9-17/h3-9,13-14,23H,10-12H2,1-2H3/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297916 (2-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-9-7-16(8-10-17)11-22-28(25,26)19-6-4-3-5-18(19)21/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297917 (CHEMBL564397 | N-{4-[(2R,6S)-2,6-dimethylmorpholin...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C21H23F3N2O4S/c1-14-12-26(13-15(2)30-14)20(27)17-8-6-16(7-9-17)11-25-31(28,29)19-5-3-4-18(10-19)21(22,23)24/h3-10,14-15,25H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297920 (3-Chloro-N-[4-(4-methylpiperazine-1-carbonyl)benzy...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C19H22ClN3O3S/c1-22-9-11-23(12-10-22)19(24)16-7-5-15(6-8-16)14-21-27(25,26)18-4-2-3-17(20)13-18/h2-8,13,21H,9-12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297915 (4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-5-3-16(4-6-17)11-22-28(25,26)19-9-7-18(21)8-10-19/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297914 (3-chloro-N-(4-((2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-8-6-16(7-9-17)11-22-28(25,26)19-5-3-4-18(21)10-19/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297922 (3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benze...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C18H19ClN2O3S/c19-16-4-3-5-17(12-16)25(23,24)20-13-14-6-8-15(9-7-14)18(22)21-10-1-2-11-21/h3-9,12,20H,1-2,10-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297905 (4-[(3-Chlorophenylsulfonamido)methyl]-N,N-diethylb...) Show SMILES CCN(CC)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C18H21ClN2O3S/c1-3-21(4-2)18(22)15-10-8-14(9-11-15)13-20-25(23,24)17-7-5-6-16(19)12-17/h5-12,20H,3-4,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50297909 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H27ClN2O3S/c1-25(20-8-4-2-3-5-9-20)22(26)18-13-11-17(12-14-18)16-24-29(27,28)21-10-6-7-19(23)15-21/h6-7,10-15,20,24H,2-5,8-9,16H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297918 (3-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(F)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C20H22ClFN2O4S/c1-13-11-24(12-14(2)28-13)20(25)16-5-3-15(4-6-16)10-23-29(26,27)17-7-8-19(22)18(21)9-17/h3-9,13-14,23H,10-12H2,1-2H3/t13-,14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297915 (4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-5-3-16(4-6-17)11-22-28(25,26)19-9-7-18(21)8-10-19/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297919 (3-Chloro-N-[4-(morpholine-4-carbonyl)benzyl]benzen...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C18H19ClN2O4S/c19-16-2-1-3-17(12-16)26(23,24)20-13-14-4-6-15(7-5-14)18(22)21-8-10-25-11-9-21/h1-7,12,20H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297917 (CHEMBL564397 | N-{4-[(2R,6S)-2,6-dimethylmorpholin...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)cc1 |r| Show InChI InChI=1S/C21H23F3N2O4S/c1-14-12-26(13-15(2)30-14)20(27)17-8-6-16(7-9-17)11-25-31(28,29)19-5-3-4-18(10-19)21(22,23)24/h3-10,14-15,25H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50297916 (2-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 |r| Show InChI InChI=1S/C20H23ClN2O4S/c1-14-12-23(13-15(2)27-14)20(24)17-9-7-16(8-10-17)11-22-28(25,26)19-6-4-3-5-18(19)21/h3-10,14-15,22H,11-13H2,1-2H3/t14-,15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297907 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclopenty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCC1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-4-3-7-18(12-16)26(24,25)21-13-14-8-10-15(11-9-14)19(23)22-17-5-1-2-6-17/h3-4,7-12,17,21H,1-2,5-6,13H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50297908 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCCC1 Show InChI InChI=1S/C21H25ClN2O3S/c22-18-6-5-9-20(14-18)28(26,27)23-15-16-10-12-17(13-11-16)21(25)24-19-7-3-1-2-4-8-19/h5-6,9-14,19,23H,1-4,7-8,15H2,(H,24,25)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50297908 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC1CCCCCC1 Show InChI InChI=1S/C21H25ClN2O3S/c22-18-6-5-9-20(14-18)28(26,27)23-15-16-10-12-17(13-11-16)21(25)24-19-7-3-1-2-4-8-19/h5-6,9-14,19,23H,1-4,7-8,15H2,(H,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297919 (3-Chloro-N-[4-(morpholine-4-carbonyl)benzyl]benzen...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C18H19ClN2O4S/c19-16-2-1-3-17(12-16)26(23,24)20-13-14-4-6-15(7-5-14)18(22)21-8-10-25-11-9-21/h1-7,12,20H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50297920 (3-Chloro-N-[4-(4-methylpiperazine-1-carbonyl)benzy...) Show SMILES CN1CCN(CC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C19H22ClN3O3S/c1-22-9-11-23(12-10-22)19(24)16-7-5-15(6-8-16)14-21-27(25,26)18-4-2-3-17(20)13-18/h2-8,13,21H,9-12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50297912 (4-[(3-Chlorophenylsulfonamido)methyl]-N-(1-adamant...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:24:25:22.23.28:29,THB:24:23:29:30.25.26,26:25:22:28.27.29,26:27:22:30.24.25| Show InChI InChI=1S/C24H27ClN2O3S/c25-21-2-1-3-22(11-21)31(29,30)26-15-16-4-6-20(7-5-16)23(28)27-24-12-17-8-18(13-24)10-19(9-17)14-24/h1-7,11,17-19,26H,8-10,12-15H2,(H,27,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50297911 (CHEMBL550065 | N-butyl-4-[(3-chlorophenylsulfonami...) Show SMILES CCCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-3-17-28(23-10-6-4-5-7-11-23)25(29)21-15-13-20(14-16-21)19-27-32(30,31)24-12-8-9-22(26)18-24/h8-9,12-16,18,23,27H,2-7,10-11,17,19H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50297909 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H27ClN2O3S/c1-25(20-8-4-2-3-5-9-20)22(26)18-13-11-17(12-14-18)16-24-29(27,28)21-10-6-7-19(23)15-21/h6-7,10-15,20,24H,2-5,8-9,16H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50297912 (4-[(3-Chlorophenylsulfonamido)methyl]-N-(1-adamant...) Show SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:24:25:22.23.28:29,THB:24:23:29:30.25.26,26:25:22:28.27.29,26:27:22:30.24.25| Show InChI InChI=1S/C24H27ClN2O3S/c25-21-2-1-3-22(11-21)31(29,30)26-15-16-4-6-20(7-5-16)23(28)27-24-12-17-8-18(13-24)10-19(9-17)14-24/h1-7,11,17-19,26H,8-10,12-15H2,(H,27,28)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50297911 (CHEMBL550065 | N-butyl-4-[(3-chlorophenylsulfonami...) Show SMILES CCCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C25H33ClN2O3S/c1-2-3-17-28(23-10-6-4-5-7-11-23)25(29)21-15-13-20(14-16-21)19-27-32(30,31)24-12-8-9-22(26)18-24/h8-9,12-16,18,23,27H,2-7,10-11,17,19H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Homo sapiens (Human))	BDBM50297910 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-16-27(22-9-5-3-4-6-10-22)24(28)20-14-12-19(13-15-20)18-26-31(29,30)23-11-7-8-21(25)17-23/h7-8,11-15,17,22,26H,2-6,9-10,16,18H2,1H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase type 2 (Mus musculus (mouse))	BDBM50297910 (4-[(3-Chlorophenylsulfonamido)methyl]-N-cyclohepty...) Show SMILES CCCN(C1CCCCCC1)C(=O)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-16-27(22-9-5-3-4-6-10-22)24(28)20-14-12-19(13-15-20)18-26-31(29,30)23-11-7-8-21(25)17-23/h7-8,11-15,17,22,26H,2-6,9-10,16,18H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...				Bioorg Med Chem Lett 19: 4455-8 (2009) Article DOI: 10.1016/j.bmcl.2009.05.033 BindingDB Entry DOI: 10.7270/Q2VT1T1D
					More data for this Ligand-Target Pair