Found 78 hits Enz. Inhib. hit(s) with all data for entry = 50041894 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cathepsin K
(Homo sapiens (Human)) | BDBM50418002
(CHEMBL1672427)Show SMILES Brc1ccc(Br)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H11Br2N3O2S/c12-8-1-2-10(13)11(5-8)19(17,18)15-9-3-4-16(6-9)7-14/h1-2,5,9,15H,3-4,6H2/t9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417996
(CHEMBL1672434)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cc(Br)ccc1Br |r| Show InChI InChI=1S/C12H13Br2N3O2S/c1-8-4-10(6-17(8)7-15)16-20(18,19)12-5-9(13)2-3-11(12)14/h2-3,5,8,10,16H,4,6H2,1H3/t8-,10+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417991
(CHEMBL1672425)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H12BrN3O2S/c12-9-2-1-3-11(6-9)18(16,17)14-10-4-5-15(7-10)8-13/h1-3,6,10,14H,4-5,7H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417991
(CHEMBL1672425)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H12BrN3O2S/c12-9-2-1-3-11(6-9)18(16,17)14-10-4-5-15(7-10)8-13/h1-3,6,10,14H,4-5,7H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417998
(CHEMBL1672426)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C13H17N3O4S/c1-19-11-3-4-12(20-2)13(7-11)21(17,18)15-10-5-6-16(8-10)9-14/h3-4,7,10,15H,5-6,8H2,1-2H3/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50418002
(CHEMBL1672427)Show SMILES Brc1ccc(Br)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H11Br2N3O2S/c12-8-1-2-10(13)11(5-8)19(17,18)15-9-3-4-16(6-9)7-14/h1-2,5,9,15H,3-4,6H2/t9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50418001
(CHEMBL1672421 | US11414402, Example 6)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417991
(CHEMBL1672425)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H12BrN3O2S/c12-9-2-1-3-11(6-9)18(16,17)14-10-4-5-15(7-10)8-13/h1-3,6,10,14H,4-5,7H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417996
(CHEMBL1672434)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cc(Br)ccc1Br |r| Show InChI InChI=1S/C12H13Br2N3O2S/c1-8-4-10(6-17(8)7-15)16-20(18,19)12-5-9(13)2-3-11(12)14/h2-3,5,8,10,16H,4,6H2,1H3/t8-,10+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417997
(CHEMBL1672423)Show InChI InChI=1S/C12H12FN3O/c13-10-3-1-9(2-4-10)12(17)15-11-5-6-16(7-11)8-14/h1-4,11H,5-7H2,(H,15,17)/t11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417998
(CHEMBL1672426)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C13H17N3O4S/c1-19-11-3-4-12(20-2)13(7-11)21(17,18)15-10-5-6-16(8-10)9-14/h3-4,7,10,15H,5-6,8H2,1-2H3/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50418002
(CHEMBL1672427)Show SMILES Brc1ccc(Br)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H11Br2N3O2S/c12-8-1-2-10(13)11(5-8)19(17,18)15-9-3-4-16(6-9)7-14/h1-2,5,9,15H,3-4,6H2/t9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417995
(CHEMBL1672433)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1C[C@H](C)N(C1)C#N |r| Show InChI InChI=1S/C14H19N3O4S/c1-10-6-11(8-17(10)9-15)16-22(18,19)14-7-12(20-2)4-5-13(14)21-3/h4-5,7,10-11,16H,6,8H2,1-3H3/t10-,11+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50418000
(CHEMBL1672432)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417989
(CHEMBL1672422 | US11414402, Example 7)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50418000
(CHEMBL1672432)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417989
(CHEMBL1672422 | US11414402, Example 7)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417991
(CHEMBL1672425)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H12BrN3O2S/c12-9-2-1-3-11(6-9)18(16,17)14-10-4-5-15(7-10)8-13/h1-3,6,10,14H,4-5,7H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50418001
(CHEMBL1672421 | US11414402, Example 6)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417996
(CHEMBL1672434)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cc(Br)ccc1Br |r| Show InChI InChI=1S/C12H13Br2N3O2S/c1-8-4-10(6-17(8)7-15)16-20(18,19)12-5-9(13)2-3-11(12)14/h2-3,5,8,10,16H,4,6H2,1H3/t8-,10+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50418001
(CHEMBL1672421 | US11414402, Example 6)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50418003
(CHEMBL1672419)Show InChI InChI=1S/C13H16N2/c14-11-15-9-8-13(10-15)7-6-12-4-2-1-3-5-12/h1-5,13H,6-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417995
(CHEMBL1672433)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1C[C@H](C)N(C1)C#N |r| Show InChI InChI=1S/C14H19N3O4S/c1-10-6-11(8-17(10)9-15)16-22(18,19)14-7-12(20-2)4-5-13(14)21-3/h4-5,7,10-11,16H,6,8H2,1-3H3/t10-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417993
(CHEMBL1672430)Show SMILES C[C@@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417990
(CHEMBL1672424)Show InChI InChI=1S/C12H14N4O/c13-9-16-7-6-11(8-16)15-12(17)14-10-4-2-1-3-5-10/h1-5,11H,6-8H2,(H2,14,15,17)/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417996
(CHEMBL1672434)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cc(Br)ccc1Br |r| Show InChI InChI=1S/C12H13Br2N3O2S/c1-8-4-10(6-17(8)7-15)16-20(18,19)12-5-9(13)2-3-11(12)14/h2-3,5,8,10,16H,4,6H2,1H3/t8-,10+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50417990
(CHEMBL1672424)Show InChI InChI=1S/C12H14N4O/c13-9-16-7-6-11(8-16)15-12(17)14-10-4-2-1-3-5-10/h1-5,11H,6-8H2,(H2,14,15,17)/t11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417990
(CHEMBL1672424)Show InChI InChI=1S/C12H14N4O/c13-9-16-7-6-11(8-16)15-12(17)14-10-4-2-1-3-5-10/h1-5,11H,6-8H2,(H2,14,15,17)/t11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417998
(CHEMBL1672426)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C13H17N3O4S/c1-19-11-3-4-12(20-2)13(7-11)21(17,18)15-10-5-6-16(8-10)9-14/h3-4,7,10,15H,5-6,8H2,1-2H3/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50418003
(CHEMBL1672419)Show InChI InChI=1S/C13H16N2/c14-11-15-9-8-13(10-15)7-6-12-4-2-1-3-5-12/h1-5,13H,6-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50418002
(CHEMBL1672427)Show SMILES Brc1ccc(Br)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H11Br2N3O2S/c12-8-1-2-10(13)11(5-8)19(17,18)15-9-3-4-16(6-9)7-14/h1-2,5,9,15H,3-4,6H2/t9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50095495
(CHEMBL262697 | Pyrrolidine-1-carbonitrile)Show InChI InChI=1S/C5H8N2/c6-5-7-3-1-2-4-7/h1-4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417989
(CHEMBL1672422 | US11414402, Example 7)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50418003
(CHEMBL1672419)Show InChI InChI=1S/C13H16N2/c14-11-15-9-8-13(10-15)7-6-12-4-2-1-3-5-12/h1-5,13H,6-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417998
(CHEMBL1672426)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C13H17N3O4S/c1-19-11-3-4-12(20-2)13(7-11)21(17,18)15-10-5-6-16(8-10)9-14/h3-4,7,10,15H,5-6,8H2,1-2H3/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50418003
(CHEMBL1672419)Show InChI InChI=1S/C13H16N2/c14-11-15-9-8-13(10-15)7-6-12-4-2-1-3-5-12/h1-5,13H,6-10H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417993
(CHEMBL1672430)Show SMILES C[C@@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM50417997
(CHEMBL1672423)Show InChI InChI=1S/C12H12FN3O/c13-10-3-1-9(2-4-10)12(17)15-11-5-6-16(7-11)8-14/h1-4,11H,5-7H2,(H,15,17)/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin C after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50418000
(CHEMBL1672432)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50417995
(CHEMBL1672433)Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1C[C@H](C)N(C1)C#N |r| Show InChI InChI=1S/C14H19N3O4S/c1-10-6-11(8-17(10)9-15)16-22(18,19)14-7-12(20-2)4-5-13(14)21-3/h4-5,7,10-11,16H,6,8H2,1-3H3/t10-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin L after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50417997
(CHEMBL1672423)Show InChI InChI=1S/C12H12FN3O/c13-10-3-1-9(2-4-10)12(17)15-11-5-6-16(7-11)8-14/h1-4,11H,5-7H2,(H,15,17)/t11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50095495
(CHEMBL262697 | Pyrrolidine-1-carbonitrile)Show InChI InChI=1S/C5H8N2/c6-5-7-3-1-2-4-7/h1-4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417990
(CHEMBL1672424)Show InChI InChI=1S/C12H14N4O/c13-9-16-7-6-11(8-16)15-12(17)14-10-4-2-1-3-5-10/h1-5,11H,6-8H2,(H2,14,15,17)/t11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50418001
(CHEMBL1672421 | US11414402, Example 6)Show InChI InChI=1S/C11H13N3O2S/c12-9-14-7-6-10(8-14)13-17(15,16)11-4-2-1-3-5-11/h1-5,10,13H,6-8H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50418000
(CHEMBL1672432)Show SMILES C[C@H]1C[C@H](CN1C#N)NS(=O)(=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C12H14BrN3O2S/c1-9-5-11(7-16(9)8-14)15-19(17,18)12-4-2-3-10(13)6-12/h2-4,6,9,11,15H,5,7H2,1H3/t9-,11+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417992
(CHEMBL1672428)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C=O |r| Show InChI InChI=1S/C11H13BrN2O3S/c12-9-2-1-3-11(6-9)18(16,17)13-10-4-5-14(7-10)8-15/h1-3,6,8,10,13H,4-5,7H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50418003
(CHEMBL1672419)Show InChI InChI=1S/C13H16N2/c14-11-15-9-8-13(10-15)7-6-12-4-2-1-3-5-12/h1-5,13H,6-10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin B
(Homo sapiens (Human)) | BDBM50417991
(CHEMBL1672425)Show SMILES Brc1cccc(c1)S(=O)(=O)N[C@@H]1CCN(C1)C#N |r| Show InChI InChI=1S/C11H12BrN3O2S/c12-9-2-1-3-11(6-9)18(16,17)14-10-4-5-15(7-10)8-13/h1-3,6,10,14H,4-5,7H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin B after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin S
(Homo sapiens (Human)) | BDBM50417988
(CHEMBL1672420)Show InChI InChI=1S/C14H18N2/c15-12-16-10-4-7-14(11-16)9-8-13-5-2-1-3-6-13/h1-3,5-6,14H,4,7-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin S after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |
Cathepsin K
(Homo sapiens (Human)) | BDBM50417988
(CHEMBL1672420)Show InChI InChI=1S/C14H18N2/c15-12-16-10-4-7-14(11-16)9-8-13-5-2-1-3-6-13/h1-3,5-6,14H,4,7-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cathepsin K after 1 hr |
ACS Med Chem Lett 2: 142-147 (2011)
Article DOI: 10.1021/ml100212k BindingDB Entry DOI: 10.7270/Q2RX9DBM |
More data for this Ligand-Target Pair | |