Compile Data Set for Download or QSAR

Found 35 hits Enz. Inhib. hit(s) with all data for entry = 50044261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010507 (CHEMBL3264374) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-20(14-17)19-7-10-28(11-8-19)12-9-25-24(29)23-16-26-21-5-3-4-6-22(21)27-23/h3-7,13-16H,8-12H2,1-2H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010505 (CHEMBL3264372) Show SMILES Fc1cc(F)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C22H20F2N4O/c23-17-11-16(12-18(24)13-17)15-5-8-28(9-6-15)10-7-25-22(29)21-14-26-19-3-1-2-4-20(19)27-21/h1-5,11-14H,6-10H2,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010506 (CHEMBL3264373) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C23H27N5O/c1-17-13-18(2)15-19(14-17)28-11-9-27(10-12-28)8-7-24-23(29)22-16-25-20-5-3-4-6-21(20)26-22/h3-6,13-16H,7-12H2,1-2H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010503 (CHEMBL3264364) Show SMILES O=C(NCCN1CCC(=CC1)c1ccccc1)c1cnc2ccccc2n1 |c:8| Show InChI InChI=1S/C22H22N4O/c27-22(21-16-24-19-8-4-5-9-20(19)25-21)23-12-15-26-13-10-18(11-14-26)17-6-2-1-3-7-17/h1-10,16H,11-15H2,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010515 (CHEMBL3264376) Show SMILES O=C(NCCN1CCC(=CC1)c1ccccc1)c1ccc2ccccc2c1 |c:8| Show InChI InChI=1S/C24H24N2O/c27-24(23-11-10-20-8-4-5-9-22(20)18-23)25-14-17-26-15-12-21(13-16-26)19-6-2-1-3-7-19/h1-12,18H,13-17H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010523 (CHEMBL3264384) Show SMILES Fc1cc(F)cc(c1)C1=CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 |t:9| Show InChI InChI=1S/C24H22F2N2O/c25-22-14-21(15-23(26)16-22)18-7-10-28(11-8-18)12-9-27-24(29)20-6-5-17-3-1-2-4-19(17)13-20/h1-7,13-16H,8-12H2,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010513 (CHEMBL3264370) Show SMILES Cc1ccc(cc1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:8| Show InChI InChI=1S/C23H24N4O/c1-17-6-8-18(9-7-17)19-10-13-27(14-11-19)15-12-24-23(28)22-16-25-20-4-2-3-5-21(20)26-22/h2-10,16H,11-15H2,1H3,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010525 (CHEMBL3264386) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 |t:9| Show InChI InChI=1S/C26H28N2O/c1-19-15-20(2)17-25(16-19)22-9-12-28(13-10-22)14-11-27-26(29)24-8-7-21-5-3-4-6-23(21)18-24/h3-9,15-18H,10-14H2,1-2H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010511 (CHEMBL3264368) Show SMILES Clc1ccc(cc1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:8| Show InChI InChI=1S/C22H21ClN4O/c23-18-7-5-16(6-8-18)17-9-12-27(13-10-17)14-11-24-22(28)21-15-25-19-3-1-2-4-20(19)26-21/h1-9,15H,10-14H2,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010504 (CHEMBL3264371) Show SMILES Fc1cc(F)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H21F2N5O/c22-15-11-16(23)13-17(12-15)28-9-7-27(8-10-28)6-5-24-21(29)20-14-25-18-3-1-2-4-19(18)26-20/h1-4,11-14H,5-10H2,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010509 (CHEMBL3264366) Show SMILES Fc1ccc(cc1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:8| Show InChI InChI=1S/C22H21FN4O/c23-18-7-5-16(6-8-18)17-9-12-27(13-10-17)14-11-24-22(28)21-15-25-19-3-1-2-4-20(19)26-21/h1-9,15H,10-14H2,(H,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010524 (CHEMBL3264385) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C25H29N3O/c1-19-15-20(2)17-24(16-19)28-13-11-27(12-14-28)10-9-26-25(29)23-8-7-21-5-3-4-6-22(21)18-23/h3-8,15-18H,9-14H2,1-2H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010514 (CHEMBL3264375) Show SMILES O=C(NCCN1CCN(CC1)c1ccccc1)c1ccc2ccccc2c1 Show InChI InChI=1S/C23H25N3O/c27-23(21-11-10-19-6-4-5-7-20(19)18-21)24-12-13-25-14-16-26(17-15-25)22-8-2-1-3-9-22/h1-11,18H,12-17H2,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010510 (CHEMBL3264367) Show SMILES Clc1ccc(cc1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22ClN5O/c22-16-5-7-17(8-6-16)27-13-11-26(12-14-27)10-9-23-21(28)20-15-24-18-3-1-2-4-19(18)25-20/h1-8,15H,9-14H2,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010512 (CHEMBL3264369) Show SMILES Cc1ccc(cc1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C22H25N5O/c1-17-6-8-18(9-7-17)27-14-12-26(13-15-27)11-10-23-22(28)21-16-24-19-4-2-3-5-20(19)25-21/h2-9,16H,10-15H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010522 (CHEMBL3264383) Show SMILES Fc1cc(F)cc(c1)N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C23H23F2N3O/c24-20-14-21(25)16-22(15-20)28-11-9-27(10-12-28)8-7-26-23(29)19-6-5-17-3-1-2-4-18(17)13-19/h1-6,13-16H,7-12H2,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010499 (CHEMBL3264363) Show SMILES O=C(NCCN1CCN(CC1)c1ccccc1)c1cnc2ccccc2n1 Show InChI InChI=1S/C21H23N5O/c27-21(20-16-23-18-8-4-5-9-19(18)24-20)22-10-11-25-12-14-26(15-13-25)17-6-2-1-3-7-17/h1-9,16H,10-15H2,(H,22,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010521 (CHEMBL3264382) Show SMILES Cc1ccc(cc1)C1=CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 |t:8| Show InChI InChI=1S/C25H26N2O/c1-19-6-8-21(9-7-19)22-12-15-27(16-13-22)17-14-26-25(28)24-11-10-20-4-2-3-5-23(20)18-24/h2-12,18H,13-17H2,1H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010517 (CHEMBL3264378) Show SMILES Fc1ccc(cc1)C1=CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 |t:8| Show InChI InChI=1S/C24H23FN2O/c25-23-9-7-19(8-10-23)20-11-14-27(15-12-20)16-13-26-24(28)22-6-5-18-3-1-2-4-21(18)17-22/h1-11,17H,12-16H2,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010519 (CHEMBL3264380) Show SMILES Clc1ccc(cc1)C1=CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 |t:8| Show InChI InChI=1S/C24H23ClN2O/c25-23-9-7-19(8-10-23)20-11-14-27(15-12-20)16-13-26-24(28)22-6-5-18-3-1-2-4-21(18)17-22/h1-11,17H,12-16H2,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010518 (CHEMBL3264379) Show SMILES Clc1ccc(cc1)N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C23H24ClN3O/c24-21-7-9-22(10-8-21)27-15-13-26(14-16-27)12-11-25-23(28)20-6-5-18-3-1-2-4-19(18)17-20/h1-10,17H,11-16H2,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010516 (CHEMBL3264377) Show SMILES Fc1ccc(cc1)N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C23H24FN3O/c24-21-7-9-22(10-8-21)27-15-13-26(14-16-27)12-11-25-23(28)20-6-5-18-3-1-2-4-19(18)17-20/h1-10,17H,11-16H2,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010508 (CHEMBL3264365) Show SMILES Fc1ccc(cc1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H22FN5O/c22-16-5-7-17(8-6-16)27-13-11-26(12-14-27)10-9-23-21(28)20-15-24-18-3-1-2-4-19(18)25-20/h1-8,15H,9-14H2,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010490 (CHEMBL3264396) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCN2C(=O)c3ccccc3C2=O)CC1 |t:9| Show InChI InChI=1S/C23H24N2O2/c1-16-13-17(2)15-19(14-16)18-7-9-24(10-8-18)11-12-25-22(26)20-5-3-4-6-21(20)23(25)27/h3-7,13-15H,8-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010520 (CHEMBL3264381) Show SMILES Cc1ccc(cc1)N1CCN(CCNC(=O)c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H27N3O/c1-19-6-10-23(11-7-19)27-16-14-26(15-17-27)13-12-25-24(28)22-9-8-20-4-2-3-5-21(20)18-22/h2-11,18H,12-17H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010528 (CHEMBL3264394) Show SMILES Fc1cc(F)cc(c1)C1=CCN(CCN2C(=O)c3ccccc3C2=O)CC1 |t:9| Show InChI InChI=1S/C21H18F2N2O2/c22-16-11-15(12-17(23)13-16)14-5-7-24(8-6-14)9-10-25-20(26)18-3-1-2-4-19(18)21(25)27/h1-5,11-13H,6-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	425	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010570 (CHEMBL3264395) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C22H25N3O2/c1-16-13-17(2)15-18(14-16)24-10-7-23(8-11-24)9-12-25-21(26)19-5-3-4-6-20(19)22(25)27/h3-6,13-15H,7-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	496	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010527 (CHEMBL3264390) Show SMILES Clc1ccc(cc1)C1=CCN(CCN2C(=O)c3ccccc3C2=O)CC1 |t:8| Show InChI InChI=1S/C21H19ClN2O2/c22-17-7-5-15(6-8-17)16-9-11-23(12-10-16)13-14-24-20(25)18-3-1-2-4-19(18)21(24)26/h1-9H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50010526 (CHEMBL3264387) Show SMILES O=C1N(CCN2CCC(=CC2)c2ccccc2)C(=O)c2ccccc12 |c:8| Show InChI InChI=1S/C21H20N2O2/c24-20-18-8-4-5-9-19(18)21(25)23(20)15-14-22-12-10-17(11-13-22)16-6-2-1-3-7-16/h1-10H,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	706	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-OPAT from human recombinant 5HT1A receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010505 (CHEMBL3264372) Show SMILES Fc1cc(F)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C22H20F2N4O/c23-17-11-16(12-18(24)13-17)15-5-8-28(9-6-15)10-7-25-22(29)21-14-26-19-3-1-2-4-20(19)27-21/h1-5,11-14H,6-10H2,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010507 (CHEMBL3264374) Show SMILES Cc1cc(C)cc(c1)C1=CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 |t:9| Show InChI InChI=1S/C24H26N4O/c1-17-13-18(2)15-20(14-17)19-7-10-28(11-8-19)12-9-25-24(29)23-16-26-21-5-3-4-6-22(21)27-23/h3-7,13-16H,8-12H2,1-2H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010506 (CHEMBL3264373) Show SMILES Cc1cc(C)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C23H27N5O/c1-17-13-18(2)15-19(14-17)28-11-9-27(10-12-28)8-7-24-23(29)22-16-25-20-5-3-4-6-21(20)26-22/h3-6,13-16H,7-12H2,1-2H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	383	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010503 (CHEMBL3264364) Show SMILES O=C(NCCN1CCC(=CC1)c1ccccc1)c1cnc2ccccc2n1 |c:8| Show InChI InChI=1S/C22H22N4O/c27-22(21-16-24-19-8-4-5-9-20(19)25-21)23-12-15-26-13-10-18(11-14-26)17-6-2-1-3-7-17/h1-10,16H,11-15H2,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010504 (CHEMBL3264371) Show SMILES Fc1cc(F)cc(c1)N1CCN(CCNC(=O)c2cnc3ccccc3n2)CC1 Show InChI InChI=1S/C21H21F2N5O/c22-15-11-16(23)13-17(12-15)28-9-7-27(8-10-28)6-5-24-21(29)20-14-25-18-3-1-2-4-19(18)26-20/h1-4,11-14H,5-10H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50010499 (CHEMBL3264363) Show SMILES O=C(NCCN1CCN(CC1)c1ccccc1)c1cnc2ccccc2n1 Show InChI InChI=1S/C21H23N5O/c27-21(20-16-23-18-8-4-5-9-19(18)24-20)22-10-11-25-12-14-26(15-13-25)17-6-2-1-3-7-17/h1-9,16H,10-15H2,(H,22,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Agonist activity at Wistar rat brain 5HT1A receptor assessed as inhibition of firing rate of dorsal raphe nucleus by electrophysiological analysis				ACS Med Chem Lett 5: 358-62 (2014) Article DOI: 10.1021/ml4004843 BindingDB Entry DOI: 10.7270/Q2QZ2CHT
					More data for this Ligand-Target Pair