Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with all data for entry = 50044454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017610 (CHEMBL3288662) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H15FN4O/c1-26-21-12-19(14-4-7-17(23)8-5-14)25-27(21)20-11-15(6-9-18(20)22(26)28)16-3-2-10-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017663 (CHEMBL3288676) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cncnc1)-c1ccccc1 Show InChI InChI=1S/C21H15N5O/c1-25-20-10-18(14-5-3-2-4-6-14)24-26(20)19-9-15(7-8-17(19)21(25)27)16-11-22-13-23-12-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017663 (CHEMBL3288676) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cncnc1)-c1ccccc1 Show InChI InChI=1S/C21H15N5O/c1-25-20-10-18(14-5-3-2-4-6-14)24-26(20)19-9-15(7-8-17(19)21(25)27)16-11-22-13-23-12-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017598 (CHEMBL3288639) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C22H16N4O/c1-25-21-13-19(15-6-3-2-4-7-15)24-26(21)20-12-16(9-10-18(20)22(25)27)17-8-5-11-23-14-17/h2-14H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017663 (CHEMBL3288676) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cncnc1)-c1ccccc1 Show InChI InChI=1S/C21H15N5O/c1-25-20-10-18(14-5-3-2-4-6-14)24-26(20)19-9-15(7-8-17(19)21(25)27)16-11-22-13-23-12-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017663 (CHEMBL3288676) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cncnc1)-c1ccccc1 Show InChI InChI=1S/C21H15N5O/c1-25-20-10-18(14-5-3-2-4-6-14)24-26(20)19-9-15(7-8-17(19)21(25)27)16-11-22-13-23-12-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017600 (CHEMBL3288644) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(F)c1 Show InChI InChI=1S/C22H15FN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017606 (CHEMBL3288656) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C22H15ClN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017610 (CHEMBL3288662) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H15FN4O/c1-26-21-12-19(14-4-7-17(23)8-5-14)25-27(21)20-11-15(6-9-18(20)22(26)28)16-3-2-10-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017661 (CHEMBL3288675) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C22H16N4O/c1-25-21-14-19(16-5-3-2-4-6-16)24-26(21)20-13-17(7-8-18(20)22(25)27)15-9-11-23-12-10-15/h2-14H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	509	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017605 (CHEMBL3288653) Show SMILES Cc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccnc1 Show InChI InChI=1S/C23H18N4O/c1-15-5-3-6-17(11-15)20-13-22-26(2)23(28)19-9-8-16(12-21(19)27(22)25-20)18-7-4-10-24-14-18/h3-14H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017606 (CHEMBL3288656) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C22H15ClN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	564	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017654 (CHEMBL3288667) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H15ClN4O/c1-26-21-12-19(14-4-7-17(23)8-5-14)25-27(21)20-11-15(6-9-18(20)22(26)28)16-3-2-10-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	645	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017601 (CHEMBL3288646) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccc(c1)S(N)(=O)=O Show InChI InChI=1S/C24H20N4O4S/c1-27-23-14-21(17-6-3-7-18(11-17)32-2)26-28(23)22-13-16(9-10-20(22)24(27)29)15-5-4-8-19(12-15)33(25,30)31/h3-14H,1-2H3,(H2,25,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	696	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017612 (CHEMBL3288664) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H17ClN4O3S/c1-27-22-13-20(14-5-8-17(24)9-6-14)26-28(22)21-12-16(7-10-19(21)23(27)29)15-3-2-4-18(11-15)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	847	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017598 (CHEMBL3288639) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C22H16N4O/c1-25-21-13-19(15-6-3-2-4-7-15)24-26(21)20-12-16(9-10-18(20)22(25)27)17-8-5-11-23-14-17/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	852	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017596 (CHEMBL3288636) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H18N4O3S/c1-26-22-14-20(15-6-3-2-4-7-15)25-27(22)21-13-17(10-11-19(21)23(26)28)16-8-5-9-18(12-16)31(24,29)30/h2-14H,1H3,(H2,24,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	884	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017654 (CHEMBL3288667) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H15ClN4O/c1-26-21-12-19(14-4-7-17(23)8-5-14)25-27(21)20-11-15(6-9-18(20)22(26)28)16-3-2-10-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017603 (CHEMBL3288649) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccnc1 Show InChI InChI=1S/C23H18N4O2/c1-26-22-13-20(16-5-3-7-18(11-16)29-2)25-27(22)21-12-15(8-9-19(21)23(26)28)17-6-4-10-24-14-17/h3-14H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017612 (CHEMBL3288664) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H17ClN4O3S/c1-27-22-13-20(14-5-8-17(24)9-6-14)26-28(22)21-12-16(7-10-19(21)23(27)29)15-3-2-4-18(11-15)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017601 (CHEMBL3288646) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccc(c1)S(N)(=O)=O Show InChI InChI=1S/C24H20N4O4S/c1-27-23-14-21(17-6-3-7-18(11-17)32-2)26-28(23)22-13-16(9-10-20(22)24(27)29)15-5-4-8-19(12-15)33(25,30)31/h3-14H,1-2H3,(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017600 (CHEMBL3288644) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(F)c1 Show InChI InChI=1S/C22H15FN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017661 (CHEMBL3288675) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccncc1)-c1ccccc1 Show InChI InChI=1S/C22H16N4O/c1-25-21-14-19(16-5-3-2-4-6-16)24-26(21)20-13-17(7-8-18(20)22(25)27)15-9-11-23-12-10-15/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017605 (CHEMBL3288653) Show SMILES Cc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccnc1 Show InChI InChI=1S/C23H18N4O/c1-15-5-3-6-17(11-15)20-13-22-26(2)23(28)19-9-8-16(12-21(19)27(22)25-20)18-7-4-10-24-14-18/h3-14H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017596 (CHEMBL3288636) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C23H18N4O3S/c1-26-22-14-20(15-6-3-2-4-7-15)25-27(22)21-13-17(10-11-19(21)23(26)28)16-8-5-9-18(12-16)31(24,29)30/h2-14H,1H3,(H2,24,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017608 (CHEMBL3288660) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C23H17FN4O3S/c1-27-22-13-20(14-5-8-17(24)9-6-14)26-28(22)21-12-16(7-10-19(21)23(27)29)15-3-2-4-18(11-15)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017603 (CHEMBL3288649) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1cccnc1 Show InChI InChI=1S/C23H18N4O2/c1-26-22-13-20(16-5-3-7-18(11-16)29-2)25-27(22)21-12-15(8-9-19(21)23(26)28)17-6-4-10-24-14-17/h3-14H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017660 (CHEMBL3288674) Show SMILES OCCn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C23H18N4O2/c28-12-11-26-22-14-20(16-5-2-1-3-6-16)25-27(22)21-13-17(8-9-19(21)23(26)29)18-7-4-10-24-15-18/h1-10,13-15,28H,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017608 (CHEMBL3288660) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C23H17FN4O3S/c1-27-22-13-20(14-5-8-17(24)9-6-14)26-28(22)21-12-16(7-10-19(21)23(27)29)15-3-2-4-18(11-15)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017665 (CHEMBL3288680) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2ccncc2c1)-c1ccccc1 Show InChI InChI=1S/C26H18N4O/c1-29-25-15-23(18-5-3-2-4-6-18)28-30(25)24-14-20(9-10-22(24)26(29)31)19-8-7-17-11-12-27-16-21(17)13-19/h2-16H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017660 (CHEMBL3288674) Show SMILES OCCn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C23H18N4O2/c28-12-11-26-22-14-20(16-5-2-1-3-6-16)25-27(22)21-13-17(8-9-19(21)23(26)29)18-7-4-10-24-15-18/h1-10,13-15,28H,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017658 (CHEMBL3288673) Show SMILES CC(=O)n1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C23H16N4O2/c1-15(28)26-22-13-20(16-6-3-2-4-7-16)25-27(22)21-12-17(9-10-19(21)23(26)29)18-8-5-11-24-14-18/h2-14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017611 (CHEMBL3288663) Show SMILES Cc1ccc2c(c1)n1nc(cc1n(C)c2=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H14FN3O/c1-11-3-8-14-16(9-11)22-17(21(2)18(14)23)10-15(20-22)12-4-6-13(19)7-5-12/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017609 (CHEMBL3288661) Show SMILES COc1ccc(cc1)-c1ccc2c(c1)n1nc(cc1n(C)c2=O)-c1ccc(F)cc1 Show InChI InChI=1S/C24H18FN3O2/c1-27-23-14-21(16-3-8-18(25)9-4-16)26-28(23)22-13-17(7-12-20(22)24(27)29)15-5-10-19(30-2)11-6-15/h3-14H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017607 (CHEMBL3288659) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(Br)c1 Show InChI InChI=1S/C22H15BrN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017604 (CHEMBL3288650) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(C)cc3n2n1 Show InChI InChI=1S/C19H17N3O2/c1-12-7-8-15-17(9-12)22-18(21(2)19(15)23)11-16(20-22)13-5-4-6-14(10-13)24-3/h4-11H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017602 (CHEMBL3288647) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1ccccc1 Show InChI InChI=1S/C24H19N3O2/c1-26-23-15-21(18-9-6-10-19(13-18)29-2)25-27(23)22-14-17(11-12-20(22)24(26)28)16-7-4-3-5-8-16/h3-15H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017599 (CHEMBL3288641) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1cccc(F)c1 Show InChI InChI=1S/C23H17FN4O3S/c1-27-22-13-20(16-5-2-6-17(24)10-16)26-28(22)21-12-15(8-9-19(21)23(27)29)14-4-3-7-18(11-14)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017597 (CHEMBL3288637) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H17N3O/c1-25-22-15-20(17-10-6-3-7-11-17)24-26(22)21-14-18(12-13-19(21)23(25)27)16-8-4-2-5-9-16/h2-15H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017597 (CHEMBL3288637) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C23H17N3O/c1-25-22-15-20(17-10-6-3-7-11-17)24-26(22)21-14-18(12-13-19(21)23(25)27)16-8-4-2-5-9-16/h2-15H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017658 (CHEMBL3288673) Show SMILES CC(=O)n1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1ccccc1 Show InChI InChI=1S/C23H16N4O2/c1-15(28)26-22-13-20(16-6-3-2-4-7-16)25-27(22)21-12-17(9-10-19(21)23(26)29)18-8-5-11-24-14-18/h2-14H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017611 (CHEMBL3288663) Show SMILES Cc1ccc2c(c1)n1nc(cc1n(C)c2=O)-c1ccc(F)cc1 Show InChI InChI=1S/C18H14FN3O/c1-11-3-8-14-16(9-11)22-17(21(2)18(14)23)10-15(20-22)12-4-6-13(19)7-5-12/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017609 (CHEMBL3288661) Show SMILES COc1ccc(cc1)-c1ccc2c(c1)n1nc(cc1n(C)c2=O)-c1ccc(F)cc1 Show InChI InChI=1S/C24H18FN3O2/c1-27-23-14-21(16-3-8-18(25)9-4-16)26-28(23)22-13-17(7-12-20(22)24(27)29)15-5-10-19(30-2)11-6-15/h3-14H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017607 (CHEMBL3288659) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccnc1)-c1cccc(Br)c1 Show InChI InChI=1S/C22H15BrN4O/c1-26-21-12-19(15-4-2-6-17(23)10-15)25-27(21)20-11-14(7-8-18(20)22(26)28)16-5-3-9-24-13-16/h2-13H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017604 (CHEMBL3288650) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(C)cc3n2n1 Show InChI InChI=1S/C19H17N3O2/c1-12-7-8-15-17(9-12)22-18(21(2)19(15)23)11-16(20-22)13-5-4-6-14(10-13)24-3/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017602 (CHEMBL3288647) Show SMILES COc1cccc(c1)-c1cc2n(C)c(=O)c3ccc(cc3n2n1)-c1ccccc1 Show InChI InChI=1S/C24H19N3O2/c1-26-23-15-21(18-9-6-10-19(13-18)29-2)25-27(23)22-14-17(11-12-20(22)24(26)28)16-7-4-3-5-8-16/h3-15H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017599 (CHEMBL3288641) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1cccc(c1)S(N)(=O)=O)-c1cccc(F)c1 Show InChI InChI=1S/C23H17FN4O3S/c1-27-22-13-20(16-5-2-6-17(24)10-16)26-28(22)21-12-15(8-9-19(21)23(27)29)14-4-3-7-18(11-14)32(25,30)31/h2-13H,1H3,(H2,25,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017665 (CHEMBL3288680) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2ccncc2c1)-c1ccccc1 Show InChI InChI=1S/C26H18N4O/c1-29-25-15-23(18-5-3-2-4-6-18)28-30(25)24-14-20(9-10-22(24)26(29)31)19-8-7-17-11-12-27-16-21(17)13-19/h2-16H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017664 (CHEMBL3288678) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2cn[nH]c2c1)-c1ccccc1 Show InChI InChI=1S/C24H17N5O/c1-28-23-13-21(15-5-3-2-4-6-15)27-29(23)22-12-17(9-10-19(22)24(28)30)16-7-8-18-14-25-26-20(18)11-16/h2-14H,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu2 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017664 (CHEMBL3288678) Show SMILES Cn1c2cc(nn2c2cc(ccc2c1=O)-c1ccc2cn[nH]c2c1)-c1ccccc1 Show InChI InChI=1S/C24H17N5O/c1-28-23-13-21(15-5-3-2-4-6-15)27-29(23)22-12-17(9-10-19(22)24(28)30)16-7-8-18-14-25-26-20(18)11-16/h2-14H,1H3,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of rat mGlu3 receptor transfected in HEK293 cells coexpressing mouse Galpha15 assessed as decrease in glutamate-induced calcium signaling ...				Bioorg Med Chem Lett 24: 2693-8 (2014) Article DOI: 10.1016/j.bmcl.2014.04.051 BindingDB Entry DOI: 10.7270/Q228094H
					More data for this Ligand-Target Pair